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Pharmacology
Ch 4 5 10 13
12
Health Care
Undergraduate 1
03/12/2009

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Cards

Term
Barbituates are...
Definition
CNS Depressants
Term
What type of tolerance means: tolerance to one equals tolerance to all others?
Definition
Cross Tolerance
Term
Sedative Hypnotics
Definition
depresses the activity of the central nervous system and is used to relieve anxiety and induce sleep.
Term
What was the first sedative hypnotic?
Definition

alcohol

Term
Veronal
Definition
1902; first barbituate; barbital
Term
Phenobarbital
Definition
1912; first commercial use sedative hypnotic
Term
Valium
Definition
1950; minor anti-neurotic, major anti-psychotic
Term
Librium
Definition
1960; first benzodiazepine
Term

Barbituates are dependent upon?

Definition

-dosage

-route of admin

-absorption rate,distrubution,metabolism,excretion

-behavorial state of individual

Term

Barbituate Classifications:

(half lifes)

Definition

Ultra-Short: 30 secs to 5 mins

Short: 5 mins to 3 hrs

Intermediate: 3-6 hours

Long: up to 10 hrs

Ultra Long: up to 3 days

(can test in urinalysis)

Term
Fat soluble vs Water soluble barbs
Definition

Fat-- Short duration; quick absorption

Water-- Longer duration; slow absorption

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