Term
| What is the difference between phentolamine and phenoxybenzamine? |
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Definition
| Phentolamine is competitive and phenoxybenzamine is noncompetitive and irreversible. |
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Term
What direct acting andrenergic agonist acts on alpha 1, alpha 2, beta 1, and beta 2 receptors? |
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Definition
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Term
| What direct acting andrenergic antagonist is used in treating asthma, POAG, anaphylactic shock, and local anaesthesia? |
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Definition
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Term
| What direct acting adrenergic antagonist acts on alpha 1, alpha 2, and beta 1 receptors? |
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Definition
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Term
| What direct acting adrenergic antagonist is useful in the treatment of shock? |
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Definition
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Term
| What two direct acting adrenergic antagonist act on the alpha 1 receptor? |
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Definition
| phenylephrine and methoxamine |
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Term
| What two direct acting adrenergic antagonists increase supraventricular tachycardia via vasoconstriction, is a nasal decongestant and induces mydriasis? |
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Definition
| phenylephrine and methoxamine |
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Term
| What direct acting andreneric agonist is alpha 2 specific and acts as a vasodilator and decreases blood pressure in hypertension? It is a nonspecific way of treating hypertension. It reduces sympathetic outflow from the brain so the overa |
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Definition
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Term
| What direct acting andrenergic agonist acts specifically on Beta 1 and Beta 2 receptors causes bronchioles to dilate in asthmatics and can stimulate the heart in cardiac arrest? |
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Definition
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Term
| What two adrenergic agonists are the drug of choice in the treatment of congestive heart failure, shock, and increase cardiac output in congestive heart failure? They act at Beta 1 receptors. |
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Definition
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Term
| What direct acting andrenergic agonist is used as a bronchodilator in the treatment of asthma and inhibits premature labor? It acts on Beta 2 receptors. It is used in inhalers (1 to 2 times a day) |
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Definition
Tertbutaline
Albuterol is also a good bronchodilator |
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Term
| What direct acting andrenergic agonist acts at the beta 2 receptor more than the Beta 1 receptor and relieves bronchospasm? |
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Definition
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Term
| What is the ability of the heart to contract stronger and cause an increase cardiac output and an increase stroke volume? |
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Definition
| positive ionotropic effect |
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Term
| What is an increase in heart rate or pulse? |
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Definition
| a positive chronotropic effect |
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Term
| What type of adrenoceptor causes vasocontriction, increased peripheral resistance, increased blood pressure, mydriasis, and increased closure of the internal sphincter of the bladder? |
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Definition
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Term
| What type of adrenoceptor causes inhibition of norepinephrine release and inhibition of insulin release? |
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Definition
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Term
| What type of adrenoreceptor causes tachycardia, increased lipolysis, increased myocardial contractility, and increased release of renin? |
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Definition
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Term
| What type of adrenoceptor causes vasodilation, slightly decreased peripheral resistance, bronchodilation, increased muscle and liver glycogenolysis, increased release of glucagon, and relaxed uterine smooth muscle? |
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Definition
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Term
| What indirect acting adrenergic agonist is used in the treatment of depression, hyperactive children, and narcolepsy? |
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Definition
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Term
| What mixed action adrenergic agonist is used in the prophylactic Tx of asthama, and increased contractility in myasthenia gravis? |
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Definition
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Term
| What do epinephrine norephinephrine, isoproterenol, and dopamine have in common? |
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Definition
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Term
| What do ephedrine, amphetamine, and phenyleprine have in common? |
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Definition
| They're not catecholamines |
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Term
What is tyramine and what is its use? |
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Definition
| Tyramine is a indirect acting andrenergic agonist. It has no therapeutic use. |
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Term
| If you apply an amphetamine to a patient with Horner's syndrome and the patient shows a reaction, what order neuron is the lesion? What if he does not show a reaction? |
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Definition
It must be a second order neuron lesion because the axon terminal of the iris is the 3rd order neuron and it responds. If the patient does not show a response, the lesion is of the 3rd order neuron. |
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Term
| If a patient were to develop cysts as a side effect to echothiophate or isofluorophate, what adrenergic agonist could you treat him with? |
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Definition
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Term
| What is the rapid desensitization to a pharmacologically or physiologically active substance, produced by inoculation with a series of small doses? |
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Definition
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Term
| What percentage of people are allergic to apraclonidine? |
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Definition
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Term
| What are the 3 general effects of alpha 1 antagonist? |
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Definition
1. decrease blood pressure
2. vasodilation
3. decrease peripheral resistance |
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Term
| How much of a difference in systolic pressure must a patient have between supine and standing positions to be considered to have orthostatic hypotension? diastolic? |
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Definition
| difference of 30 systolic and 50 diastolic |
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Term
| What adrenergic antagonist is an alpha 1 and alpha 2 blocker, long lasting, and used to treat pheochromocytoma (when the adrenal release tons of catecholamines) norepi and epi receptors in an irreversible noncompetitive blockade? |
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Definition
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Term
| What adrenergic antagonist is an alpha 1 and alpha 2 blocker but is short lived an dused in the diagnosis of pheochromocytoma? |
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Definition
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Term
| What three andrenergic antagonist are specific for alpha 1 receptors, decrease peripheral resistance and blood pressure, have little effect on cardiac output and are used in the treatment of hypertension? |
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Definition
prazosin
terazosin
doxazosin |
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Term
| What andrenergic antagonist is selective against alpha 2 receptors and used to treat impotence? |
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Definition
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Term
| Which andrenergic antagonist is a a nonselective Beta 1 and Beta 2 blocker and is used in the treatment of hypertension, glaucoma, angina, myocaridal infarction, migraine, and hyperthyroidism? |
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Definition
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Term
| Which andrenergic antagonist is a nonselective Beta 1 and Beta 2 blocker and is ronic open used in the treatment of hypertension and chronic open angle glaucoma? |
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Definition
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Term
| Which adrenergic antagonist is a nonselective Beta 1 and Beta 2 blocker and is used in the treatment of hypertension, anina, migraine, and has a protective effect on the myocardium? |
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Definition
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Term
| Which 4 andrenergic antagonist is a selective Beta 1 blocker and used in the treatment of hypertension in patients with asthma (or COPD) or with diabetes mellitus and also has some intrinsic agonist activity? |
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Definition
Acebutolol
Atenolol
Metoprolol
Esmolol
MAAE |
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Term
What does it mean that pindolol and acebutolol are Beta 1 and Beta 2 adrenergic antagonists with partial agonist activity? |
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Definition
| They inhibit the Beta 1 and Beta 2 receptors but they stimulate the sympathetic nervous system. |
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Term
| What effect does the intrinsic sympathmimetic activity (ISA) have on the Beta 1 and Beta 2 partial agonist? |
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Definition
| There is less of a decrease in heart rate. |
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Term
| What andrenergic Beta 1 and Beta 2 partial agonist is used in treating hypertension with moderate bradycardia, and the treatment of diabetes mellitus? |
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Definition
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Term
| What andrenergic antagonist blocks alpha 1, alpha 2, and beta 2 receptors, causes vasodilation, decreases blood pressure, treates hypertension especially in African Americans and pregnancy induced hypertension? |
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Definition
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Term
What is special about African American hypertensive patients? |
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Definition
| Beta blockers do not work as well |
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Term
| Which andrenergic antagonist blocks norepinephrine reuptake and acts as a local anaesthetic? |
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Definition
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Term
| Which andrenerigic antagonist causes a gradual decrease in blood pressure with decreased heart rate and is rarely used now to treat hypertension? |
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Definition
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Term
| Which andrenergic antagonist effects the neurotransmitter uptake or release, causes a gradual decrease in blood pressure, with a decreased heart rate, and is used in the treatment of hypertension? |
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Definition
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