| Term 
 
        | What are the side effects of Sulfonlyureas?  (3) |  | Definition 
 
        | Hypoglycemia, cardiotoxicity and weight gain (10#+) |  | 
        |  | 
        
        | Term 
 
        | What do sulfonlyureas help do and what is an contraindication? |  | Definition 
 
        | Promote insulin release and allergy is a problem to sulfa |  | 
        |  | 
        
        | Term 
 
        | What do meglitinides do and what is the prototype? |  | Definition 
 
        | Stimulate pancreatic insulin release.  Repaglinide is prototype |  | 
        |  | 
        
        | Term 
 
        | What is the side effect of meglitinides and what do you not give sulfonlyureas with meglitinides? |  | Definition 
 
        | Side effect: hypoglycemia.  Don't give together because they have the same action. |  | 
        |  | 
        
        | Term 
 
        | Insulin Glargine: How long does it last?  When do you usually give it?  Can it be mixed with other insulin? |  | Definition 
 
        | Lasts 24+ hrs.  $$$  given at bedtime as basal dose and CAN NOT be mixed |  | 
        |  | 
        
        | Term 
 
        | Lispro insulin (Humalog) what's the onset and how long does it last? |  | Definition 
 
        | very rapid onset and shorter duration than regular insulin and more $ |  | 
        |  | 
        
        | Term 
 
        | Insulin aspart: how quick and how long do it last? |  | Definition 
 
        | Very fast and short but $$ |  | 
        |  | 
        
        | Term 
 
        | NPH Insulin:  Can it be mixed?  How long and how fast? |  | Definition 
 
        | Cloudy, longer onset and action CAN be mixed with regular insulin |  | 
        |  | 
        
        | Term 
 
        | Tell me about Lente and ultralente insulin compared with NPH.  Can it be mixed with others? |  | Definition 
 
        | less allergic than NPH but CAN NOT be mixed with others. |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Decreases production of glucose by the liver used to prevent type 2 DM |  | 
        |  | 
        
        | Term 
 
        | What are some side effects of Metformin?  What really needs to be healthy to be Rx this? |  | Definition 
 
        | SE: decreased appetite, N and diarrhea.  NND healthy kidneys for excretion |  | 
        |  | 
        
        | Term 
 
        | What does the drug Acarbose do? |  | Definition 
 
        | Delays absorptoin of Carbs. |  | 
        |  | 
        
        | Term 
 
        | What are some side effects of Acarbose and what organ does it affect mostly? |  | Definition 
 
        | flatulence, cramps, diarrhea, bloating, loud bowel sounds (borborygmus)  Long term use impact liver |  | 
        |  | 
        
        | Term 
 
        | What are glucocortoids? and what are they used for? |  | Definition 
 
        | they are stress hormones, carb, fat and protein metabolism.  They are used for replacement therapy and for autoimmune therapy: allergy, Reumatoid arthi or SLE for example |  | 
        |  | 
        
        | Term 
 
        | What are some side effects of glucocortoids? |  | Definition 
 
        | adrenal insufficiency, osteoporosis, elevated blood sugar, risk of infections and slow healing |  | 
        |  | 
        
        | Term 
 
        | Name some side effects of androgens. |  | Definition 
 
        | Virilization (2ndary sex changes, premature bone closure, choleterol changes and edema |  | 
        |  | 
        
        | Term 
 
        | Name some uses for androgens. |  | Definition 
 
        | Replacement therapy, use in breast cancer, sex drive stimulant, muscle bulking agent and delay puberty |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Maintains bone mass and lowers cholesterol |  | 
        |  | 
        
        | Term 
 
        | Name some side effects of esterogen. |  | Definition 
 
        | endometrial, overian and breast cancer, N |  | 
        |  | 
        
        | Term 
 
        | What are some uses of estrogen. |  | Definition 
 
        | Replacement therapy and tx of prostate cancer |  | 
        |  | 
        
        | Term 
 
        | What does progestin cause and what are some side effects? |  | Definition 
 
        | causes bleeding.  SE: breast tenderness, spotting, amenorrhea |  | 
        |  | 
        
        | Term 
 
        | Progestin is used for...... |  | Definition 
 
        | PMS tx, endometrosis, uterine bleeding |  | 
        |  | 
        
        | Term 
 
        | What are the first and second generation antihistamines? |  | Definition 
 
        | 1st-diphenhydramine (Benadryl) 2nd- Fexofenadine (Allegra)
 |  | 
        |  | 
        
        | Term 
 
        | Name some uses for antihistimes |  | Definition 
 
        | allergy, motion sickness, insomnia, cold systoms |  | 
        |  | 
        
        | Term 
 
        | Name some drug interactions for antihistimes. |  | Definition 
 
        | alochol, 2nd yeast and some antibiotics result in dysrythmias |  | 
        |  | 
        
        | Term 
 
        | Birth control may do what? |  | Definition 
 
        | Raise blood sugar and BP, risk of multiple births when first discontinued. |  | 
        |  | 
        
        | Term 
 
        | Name the two major drug groups for asthma. |  | Definition 
 
        | Anti-inflammatory and bronchodilators |  | 
        |  | 
        
        | Term 
 
        | What are the anti-inflammatory drugs for asthma? |  | Definition 
 
        | Glucocortoids and Leukotriene modifiers |  | 
        |  | 
        
        | Term 
 
        | What are the bronchodilators drugs for asthma? |  | Definition 
 
        | Beta 2 Agonists, anticholingerics and Theophylline |  | 
        |  | 
        
        | Term 
 
        | Uses of Beta 2 Agonists.  What is the prototype? |  | Definition 
 
        | Asthma, COPD, bronchodilation and stopping of uterine contractions//// Albuterol
 |  | 
        |  | 
        
        | Term 
 
        | Name some asthma management techniques. (3) |  | Definition 
 
        | 1. Monitoring lung function: Flow meter  2. Stepped care  3. Avoid triggers  3. Hydration (thins mucous) |  | 
        |  | 
        
        | Term 
 
        | Nasal decongestrants are usually what type of drugs? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Name the three types of cough meds and define each. |  | Definition 
 
        | 1. anti-tussive- cough suppresant 2. expectorant- Gets mucous up and out
 3. mucolytics- breaks down mucous, make thinner
 |  | 
        |  | 
        
        | Term 
 
        | What are some side effects of Albuterol? |  | Definition 
 
        | CNS and CV stimulatin often tremors because they are beta 2 agonists |  | 
        |  | 
        
        | Term 
 
        | Albuterol is used for what kind of situations? |  | Definition 
 
        | For exercise PRN ans emerg. med. |  | 
        |  | 
        
        | Term 
 
        | What are some uses of Cimetadine (Tagamet)? |  | Definition 
 
        | ulcers, reflux, indigestion, and aspiration pneumonitis |  | 
        |  | 
        
        | Term 
 
        | What are the side effects of Cimetadine? |  | Definition 
 
        | Anti-andogenic properties (fat pad shifting, gynemastocia (boobs) and CNS effects (confusion, hallucinations, depression) |  | 
        |  | 
        
        | Term 
 
        | What is so good about Ranitidine (Zantac)? |  | Definition 
 
        | More potent, fewer side effects and drug interactions |  | 
        |  | 
        
        | Term 
 
        | Omeprazole (Prilosec) is what kind of drug and what SE's does it have? |  | Definition 
 
        | Proton pump inhibitor (PPI) SE: headache, diarrhea, N and V |  | 
        |  | 
        
        | Term 
 
        | What do you have to beware when giving Sucralfate? |  | Definition 
 
        | It will bind with other meds and minerals so you have to give it alone.  Give with adequate H2O |  | 
        |  | 
        
        | Term 
 
        | What is the side effect of Sucralfate? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are the side effects of antacids (2) |  | Definition 
 
        | Constipation and diarrhea |  | 
        |  | 
        
        | Term 
 
        | What should you not do when you take an antacid? |  | Definition 
 
        | Do not take it with other meds as impairs absorption |  | 
        |  | 
        
        | Term 
 
        | What are these ingredients (Na, Mg, Ca) contraindicated for what kind of patients? |  | Definition 
 
        | Na for heart and blood pressure///Mg for renal///Ca for kidney stones |  | 
        |  | 
        
        | Term 
 
        | Define bulk formers?  Can they be dosed to regulate consistency? |  | Definition 
 
        | increase bulk and weight by water retention so gravity says downhill////Yes |  | 
        |  | 
        
        | Term 
 
        | What type of laxative would you want to give to a heart patient or the elderly? |  | Definition 
 
        | Bulk former so no strain. |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Define stimulants.  What is bad about them? |  | Definition 
 
        | Stimulate muscle and H2O retention but cramps and fat vit. losses |  | 
        |  | 
        
        | Term 
 
        | What type of laxative draw H2O into stool?  What kind of problem does it have? |  | Definition 
 
        | Osmotics.  Problem: W/ electrolytes (K,Mg) hard on heart and kidney patients |  | 
        |  | 
        
        | Term 
 
        | What cleanses bowel for X-ray but it doesn't give cramps or has electrolyte losses?  How is it dosed? |  | Definition 
 
        | Golytely///Drink 3L in 3 hrs ( 1C every 15 mins ) |  | 
        |  | 
        
        | Term 
 
        | What are three non drug helps for relieving constipation? |  | Definition 
 
        | hydration, exercise, fiber |  | 
        |  |