Shared Flashcard Set

Details

PHARMACOLOGY
EXAM 3- DRUG ADVERSE EFFECT
22
Nursing
Professional
03/27/2012

Additional Nursing Flashcards

 


 

Cards

Term
HEPATITIS B VACCINE (ENGERIX-B, RECOMBIVAX HB)
Definition

 pain at injection site, tacycardia, hypotension, urticaria, pulmonary congestion, skin rashes, bruising/bleeding, anaphylactic shock

 

*gingivitis or white patches in mouth, vaginal yeast infection

 

* disorientation, confusion, slurred speech changes in mood/behavior

Term
interferon
Definition

* depression/suicidal ideations

 

* joint pain, flu-like sypmtoms

 

* arthralgia

Term

cyclosporine (neoral, sandimmune)

 

Definition

75% of patients--urinary retention

50%-- hypertension and tremor

gingival hyperplasia and elevated hepatic enzymes

 

* increased risk of lymphomas/skin cancers

 

* increased risk of oral candidiasis and gingivitis

Term
IBP (advil, motrin, others)
Definition

nausea, heartburn, epigastric pain, dizziness

 

GI ulceration with occult or gross bleeding

 

chronic use = renal impairment

 

BLACK BOX warning: treatment of perioperative pain due to coronary artery bypass surgery due to potential for stroke or MI

Term
prednisone
Definition

* long term= cushing's syndrome, gastric ulcers

 

* increased BP, hypertension, tachycardia (due to fluid retention)

 

* affect bone metabolism=osteoporosis/fractures

 

* glaucoma, rainbow halos around lights, vision impairment

Term
acetaminophen (tylenol, others)
Definition

* malnourished patients (could cause renal failure/death)

 

* liver failure, ototoxic

 

* pulmonary congestion or edem

 

* dark/tarry stools, hematemesis or coffe-ground emesis, blood in stool

Term
penicillin
Definition

* anaphylaxis (most serious)

 

*diarrhea, nausea, and vomitting

 

* reduce effectivness of oral contraceptives

Term
cefotaxime
Definition

* minor rash/itching-possible anaphylaxis

 

* considerable pain at injection site

 

 

 

Term
tetracycline
Definition

* affects vaginal, oral, and intestinal flora (superinfections)

 

* epigastric burning and diarrhea may be severe enough to stop therapy

 

* discoloration of teeth, fetal bone growth/teeth

 

* photosensitivity

Term
erythromycin
Definition

* hepatotoxicity caused by estolate salt of the drug (most severe)

 

* hearing loss, vertigo, dizziness (with high doses)

Term
gentamicin
Definition

* rash, nausea, vomiting and fatigue

 

* nephrotoxicity may occur in patients with pre-existing kidney impairment

Term
ciprofloxacin
Definition

* phototoxicity, headache, dizziness

 

BLACK BOX warning: may cause tendon inflammation and rupture

Term

tmp-smz

 

Definition

* skin rash, itching, fever

 

* oliguria/renal failure have been reported

 

* agranulocytosis and thrombocytopenia

 

* photosensitivity (avoid direct sunlight)

Term
isoniazid
Definition

* numbness of hands/feet, rash and fever

 

* BLACK BOX warning: severe/fatal hepatitis has been reported

 

*jaundice, fatigue, loss of appetite

 

* blurred vision, decreased hearing, increased bleeding

 

* hepatic/renal toxic

 

Term
diphenhydramine
Definition

* anticholinergic effects: dry mouth, tachycardia, mild hypo

 

*orthostatic hypertension

 

*increased intraocular pressure in pts with narrow-angled glaucoma

 

* hepatic toxicity, thickend mucus, urinary retention

Term
fluticasone
Definition

* swallowing large amounts = systemic corticosteroid

 

* nasal irritation and epitaxis

Term
oxymethazoline
Definition

* rebound congestion is common if used longer than 3-5 days

 

* minor stinging/dryness in nasal mucosa

 

* tachycardia/dysrhythmias in pts with history of cardiac disease

Term
dextromethorphan
Definition

* dizziness, drowsiness, and GI upset

 

*if ABUSED: CNS toxicity: slurred speech, ataxia, hyperexcitability, stupor, respiratory depression, seizures, coma and toxic psychosis

Term
salmeterol
Definition

* headaches, throat irritation, tremor, nervousness, restlessness

 

* patients with "heart disease" should be monitored regularly( tacycardia)

 

* BLACK BOX warning: LABAs may increase the risk of asthma related death

Term
ipratropium
Definition

* irritation of the upper respiratory tract= cough, drying of nasal mucosa

 

* produces bitter taste-rinse mouth

Term
beclomethasone
Definition

* may mask signs of infection (do NOT use if active infection)

 

* prolonged use--oropharyngeal candidiasis

 

* corticosteroid toxicity with prolonged use

Term
zafirlukast
Definition

* headache is most common

 

* nausea and diarrhea

 

* tachycardia, palpations, blurred vision or headaches

Supporting users have an ad free experience!