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Pharmacology
Chapter 2
21
Nursing
Undergraduate 1
01/27/2012

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Term
Therapeutic Classification of Drugs
Definition
Method for organizing drugs on the basis of their clinical usefulness
Term
Therapeutic Drug Examples
Definition
Anticoagulants, Antidepressants, Antihypertensives, Antibiotics
Term
Pharmacologic Classification of Drugs
Definition
Method for organizing drugs on the basis of their mechanism of action
Term
Pharmacologic Drug Examples
Definition
Diuretics, Calcium channel blocker, Vasodilator, Adrenergic antagonist
Term
Prototype Drug
Definition
Well-understood model drug with which other drugs in a pharmacologic class may be compared
Term
Chemical Name
Definition
Strict chemical nomenclature used for naming drugs established by the International Union of Pure and Applied Chemistry; describes physical and chemical properties; drug has only one chemical name
Term
Chemical Group Name
Definition
Drugs are sometimes classified by a portion of their chemical structure (i.e. cephalosporins, phenothiazines, benzodiazepines)
Term
Generic Name
Definition
Assigned by the US Adopted Name Council; less complicated and easier to remember; drug has only one generic name which is written in lower case
Term
Trade Name
Definition
Assigned by the company marketing the drug; drug developer has exlusive rights to name and market a new drug for 17 years in US; drug has several trade names which are capitalized
Term
Combination Drug
Definition
Drug product with more than one active generic ingredient
Term
Bioavailability
Definition
The physiologic ability of the drug to reach its target cells and produce its effect; key to comparing generic vs. trade-name drugs
Term
Negative Formulary List
Definition
List of trade-name drugs that pharmacists may not dispense as generic drugs
Term
Addiction
Definition
The overwhelming feeling that drives a person to use a drug repeatedly
Term
Dependence
Definition
A physiologic or psychological need for a substance
Term
Physical Dependence
Definition
An altered physical condition caused by the adaptation of the nervous system to repeated drug use
Term
Withdrawal
Definition
The individual expresses physical signs of discomfort when the drug is no longer available
Term
Psychologically Dependent
Definition
Little physical discomfort when drug is withdrawn, but intense compelling desire to continued use
Term
Scheduled Drugs
Definition
In the US, describes a drug based on its potential for misuse or abuse and is placed into one of five categories (Schedule 1 drugs have the highest potential for abuse and have limited or no therapeutic use)
Term
Controlled Substance
Definition
Drug whose use is restricted by the Controlled Substances Act of 1970 and later revisions; have high potential for addiction or dependence; placed into one of five schedules
Term
Canadian Schedule of Drugs
Definition
Only use three levels of classification; all prescription drugs are in level 1
Term
Mechanism of Action
Definition
The way in which a drug exerts its effects.
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