Term
| Inflammation is a _______ response to tissue injury caused by physical trauma, noxious chemicals or microbiologic agents |
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Definition
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Term
| _______ is the body’s effort to inactivate or destroy invading organisms, remove irritants and set the stage for tissue repair |
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Definition
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Term
| Inflammation usually _______ when healing is complete. |
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Definition
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Term
| Inflammatory responses are defense mechanisms are capable of causing _______ tissue injury |
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Definition
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Term
| Mediators of inflammation include _______, _______, _______, and _______. |
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Definition
| Lipids; Amines; Small peptides; Large peptides |
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Term
| Two lipids which are mediators of inflammation are _______ and _______. |
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Definition
| Prostaglandins; Leukotrienes |
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Term
| The primary amine involved in inflammation is _______. |
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Definition
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Term
| The small peptide involved in inflammation is _______, while the large peptide is _______. |
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Definition
| Bradykinin; Interleukin-1 |
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Term
| Prostaglandins are _______, they are made at the site at which they create their effects. |
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Definition
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Term
| Prostaglandins _______ circulate in the blood in significant quantities. |
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Definition
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Term
| Prostaglandins are _______ to inactive products at their site of action. |
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Definition
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Term
| Prostaglandins are Produced in minute quantities by _______. |
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Definition
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Term
| Prostaglandins act _______, on tissues where they are produced. |
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Definition
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Term
| Prostaglandins are released in _______ or _______ processes. |
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Definition
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Term
| Many NSAIDs work by inhibiting synthesis of _______. |
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Definition
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Term
| NSAIDS inhibit _______ but not _______ enzymes. |
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Definition
| Cyclooxygenase; Lipoxygenase |
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Term
| _______ is constitutive, while _______ is inducible and associated with inflammation |
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Definition
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Term
| Side-effect of _______ inhibition is inability to form stomach protecting prostaglandins. |
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Definition
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Term
| NSAIDs have differing _______ , _______ and _______ activities |
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Definition
| Antipyretic; Analgesic; Anti-Inflammatory |
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Term
| Aspirin _______ inactivates cyclooxygenase. |
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Definition
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Term
| Aspirin is rapidly deacetylated by esterases to form _______. |
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Definition
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Term
| What drug has antipyretic/anti-inflammatory effects due to blockade of prostaglandin synthesis at the thermoregulatory centers in the hypothalamus and at peripheral target sites? |
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Definition
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Term
| Aspirin _______ induce remission in Arthritis. |
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Definition
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Term
| Aspirin and other salicylates are _______ than opioids in pain with inflammation involved. |
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Definition
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Term
| Aspirin causes _______ and sweating to help dissipate heat in febrile patients. |
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Definition
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Term
| Aspirin has _______ effect on normal body temperature. |
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Definition
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Term
| Aspirin in higher doses works on the respiratory center in medulla causing _______ and respiratory _______ usually compensated for by the kidneys. |
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Definition
| Hyper ventilation; Alkalosis |
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Term
| toxic levels of Aspirin and other Salicylates produce _______. |
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Definition
| Central Respiratory Paralysis |
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Term
| Prostacyclin _______ gastrin secretion. |
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Definition
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