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Pharmacology
Test 1 pharmacology Baptist Health LVN
54
Nursing
Professional
11/08/2009

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Cards

Term
Pt is admitted to L&D with true preterm labor with cervical change have no contraindication, they become candidates for tocolytic therapy, what is it?
Definition
Drug therapy to decrease uterine muscle contractions using beta2-adrenergic receptor agonists (terbutaline, Brethine) or the calcium antagonist magnesium sulfate. The goals are to: 1. Interrupt or inhibit uterine contractions to create additional time for fetal maturation in utero, 2. Delay delivery so antenatal corticosteroids can be delivered to facilitate fetal lung maturation and 3. Allow safe transport of the mother to an appropriate facility if required.
Term
What is PIH? What does it do and what is it treated with?
Definition
Pregnancy induced hypertension, gestational hypertension: elevated blood pressure without proteinuria after 20 gestational weeks in clients normotensive prior to pregnancy; nonpharmacologic treatments include activity reduction, lying on the left side, increased dietary protein (supplemental 90 g/day), psychosocial therapy and biofeedback; methyldopa (aldomet), hydralazine (apresoline), and Labetalol (trandate) are considered first line therapy for preeclampsia, additional alternatives include beta blockers, prazosin, nifedipine and clonidine; magnesium sulfate and hydralazine are the two most common
Term
What is antibiotic peak?
Definition
indicates how much of the antibiotic has actually peaked in the system, obtained 30 mins after administration
Term
What is antibiotic trough?
Definition
indicates how much has been metabolized by the body system, obtained 30 mins before administration
Term
What is drug toxicity?
Definition
can be identified by monitoring the therapeutic range of the drug, can involve the liver, kidneys, CNS and other systems
Term
If pt is allergic to pcn and has an order for it, what do you do?
Definition
Call the physician
Term
When taking an antibiotic what do you advise the pt?
Definition
Finish the entire prescription even if you feel better
Term
What are the side effects of cephalosporins?
Definition
GI disturbances (nausea, vomiting, diarrhea), alteration in blood clotting time (increased bleeding) with administration of large doses, and nephrotoxicity (toxicity to the kidney) in individuals w/ a preexisting renal disorder
Term
What is thrush and the proper course of action?
Definition
Candidiasis of the oral cavity, characterized by small whitish eruptions on the mouth, throat and tongue; call the doctor
Term
Pt is ER w/ high fever, rash and headache. DX bacterial infection, what is prescribed?
Definition
Broad spectrum antibiotic (tetracycline, cephalosporins)
Term
Allergy or hypersensitivity to PCN, what is given?
Definition
Erythromycin (macrolide)
Term
What are the side effects of azithromycin (Zithromax)?
Definition
Hepatotoxicity (liver toxicity), monitor liver enzymes
Term
What are the side effects of tetracycline?
Definition
GI disturbances, photosensitivity, irreversibly discolors permanent teeth, superinfection
Term
What are the side effects of aminoglycosides?
Definition
Ototoxicity, nephrotoxicity
Term
Pt is diabetic and diagnosed with a serious infection and prescribed Levaquin, what labs do you check?
Definition
BUN and serum creatinine to determine renal function and too much sugar, levels will be up
Term
Sulfonamides can cause crystalluria, what patient teaching needs to be done?
Definition
Drink lots of water, increasing fluid intake dilutes the drug helping to prevent crystalluria
Term
What do you teach a pt about photosensitivity?
Definition
Advise client to wear sunglasses, avoid direct sunlight, and use sun block and protective clothing to decrease the risk of photosensitive reactions
Term
How often would a medication with a short half life be taken?
Definition
Twice daily
Term
What is the tetracycline dosing for acne?
Definition
Low doses over months
Term
When should tetracycline be taken for best absorption?
Definition
One hour before or two hours after meals with a full glass of water
Term
When taking methoxsalen for psoriasis, what are some precautions to take for side effects?
Definition
Avoid sunlight, sunlight could cause burning and blistering
Term
How does minoxidil work?
Definition
Minoxidil causes vasodilation, increasing cutaneous blood flow
Term
For a Coumadin pt, the antidote for overdose is Vitamin K, but it takes 24-48 hours to be effective. What should this pt avoid while taking coumadin?
Definition
Greens which are high in vit k
Term
Pts on pilocarpine for glaucoma are contraindicated by which pts?
Definition
ASTHMATICS, htn, corneal abrasion, hyperthyroidism, coronary vascular disease, urinary tract obstruction, gastrointestinal obstruction, ulcer disease, parkinsonism, and bradycardia
Term
Topical anesthetics are used in selected aspects of a comprehensive eye exam and in the removal of foreign bodies from the eye. What does it cause?
Definition
The blink reflex is temporarily lost, therefore the corneal epithelium is not kept moist.
Term
Ocular Therapeutic System:
(Ocusert: pilocarpine: ocular therapeutic system: Ocusert is a wafer thin disk impregnated with time release pilocarpine. The disk is replaced every 7 days. Clients should check for the presence of the ocusert disk in the conjunctival sac daily at bedtime and on awakening. The onset of action is unknown(1hr), the peak is 1.5-2 hrs, and the duration of action is 7 days)
Definition
EXCEPT: to recommend early morning insertion
Term
9 month old in ER with otitis media, what is the first line of treatment?
Definition
Amoxicillin (Amoxil, Augmentin)
Term
Systemic absorption is possible but not common with the use of miotics. How would the nurse reduce systemic absorption of eye drops?
Definition
Gently apply pressure to the lacrimal duct (passage that carries tears into the nose)
Term
Systemic absorption is possible but not common with the use of miotics. How would the nurse reduce systemic absorption of eye drops?
Definition
Gently apply pressure to the lacrimal duct (passage that carries tears into the nose)
Term
Oral contraceptives can cause clotting and should not be taken by these pts due to increasing the risk of clotting?
Definition
Obese patients
Term
What are the symptoms reported in menopause?
Definition
Sudden episodes of vasolilation(HOT FLASHES), changing menses, and vaginal dryness
Term
What is the clearest indication for androgen therapy?
Definition
Hypogonadism, occurs when there is insufficient testosterone production by the testes
Term
How do we take synthetic androgen?
Definition
Take with food or milk to decrease GI upset
Term
What are the physical effects of virilization?
Definition
The development of male sex characteristics such as hirsutism(increased male hair growth patterns)
Term
What is most commonly abused by athletes?
Definition
Steriods
Term
Pt is admitted to L&D with true preterm labor with cervical change have no contraindication, they become candidates for tocolytic therapy, what is it?
Definition
Drug therapy to decrease uterine muscle contractions using beta2-adrenergic receptor agonists (terbutaline, Brethine) or the calcium antagonist magnesium sulfate. The goals are to: 1. Interrupt or inhibit uterine contractions to create additional time for fetal maturation in utero, 2. Delay delivery so antenatal corticosteroids can be delivered to facilitate fetal lung maturation and 3. Allow safe transport of the mother to an appropriate facility if required.
Term
What is PIH? What does it do and what is it treated with?
Definition
Pregnancy induced hypertension, gestational hypertension: elevated blood pressure without proteinuria after 20 gestational weeks in clients normotensive prior to pregnancy; nonpharmacologic treatments include activity reduction, lying on the left side, increased dietary protein (supplemental 90 g/day), psychosocial therapy and biofeedback; methyldopa (aldomet), hydralazine (apresoline), and Labetalol (trandate) are considered first line therapy for preeclampsia, additional alternatives include beta blockers, prazosin, nifedipine and clonidine; magnesium sulfate and hydralazine are the two most common
Term
What is potocin?
Definition
Potocin is the synthetic form of oxytocin which is a uterotropic drug that enhances uterine contractility by stimulating the smooth muscle of the uterus. Used for labor induction and labor augmentation(stimulation of effective uterine contractions once labor has begun). A pt with uterine inertia (uterine activity or hypotonic contractions) may be more responsive to oxytocin than the pt who has not begun labor.
Term
What are the indications for labor induction?
Definition
Pregnancy-induced hypertension, chronic hypertension, membrane rupture >24hrs, chorioamnionitis, postdates(>42 weeks gestation), intrauterine growth retardation(IUGR), positive contraction stress test (CST), maternal diabetes mellitus (classes B-F), maternal renal disease, isoimmunization, intrauterine fetal death
Term
What is the most common bacteria that causes UTI?
Definition
For both lower UTI (acute cystitis) and upper UTI (acute pyelonephritis), Escherichia coli is the most common organism that causes UTIs.
Term
What are the side effects of macrodantin (nitrofurantoin, furalan) used to treat UTI
Definition
Anorexia, nausea, vomiting, rust/brown discoloration of urine, diarrhea, rash, pruritus, dizziness, headache, drowsiness, discoloration of teeth if taking orally without rinsing, avoid antacids because they interfere with drug absorption, and do not crush tabs. Also, increase fluids and take drug with food to minimize GI upset
Term
What is trimethoprim? Why is it used as a combo?
Definition
Trimethoprim (proloprim, trimpex) can be used alone to treat UTIs, although it is usually used in combination with a sulfonamide, sulfamethoxazole (the combined preparation is generically called co-trimoxazole (bactrim, septra), or TMP/SMZ), to prevent the occurrence of trimethoprim resistant organisms. This drug combo produces slow acting bactericidal effects against most gram + and gram- organisms.
Term
What is the dosing for mycostatin (nystatin)?
Definition
Mycostatin is a poylene antifungal drug that is administered orally or topically to treat candidal infection, the normal po dosage is 400,000-600,000 units q6-8hr
Term
What is the purpose of urinary analgesics?
Definition
Urinary analgesics are used to relieve the pain, burning sensation and frequency and urgency of urination that are symptomatic of lower UTIs.
Term
What are the side effects of pyridium (phenazopyridine)?
Definition
The drug can cause GI disturbances, hemolytic anemia, nephrotoxicity and hepatotoxicity, the urine becomes a harmless reddish orange because of the dye, it can also alter the glucose urine test
Term
What is urecholine used for?
Definition
Urecholine (bethanechol chloride), is a parasympathomimetic (cholinomimetic) that may be used to stimulate micturition (urination); the drug action is to increase bladder tone by increasing tone of the detrusor urinal muscle which produces a contraction strong enough to stimulate urination
Term
What is the purpose of detrol (tolterodine tartrate)?
Definition
Detrol is an antimuscarinic (agent that blocks parasympathetic nerve impulses)/anticholinergic used to control an overactive bladder, also decreases urge urinary incontinence.
Term
What are the symptoms of pyelonephritis?
Definition
Symptoms of an upper UTI, would include chills, high fever, flank pain, pain during urination, urinary frequency and urgency, and pyuria.
Term
What is the purpose of urinary antiseptics in low doses?
Definition
They have a bacteriostatic effect (inhibit bacterial growth)
Term
What do you notice most about the medications generic spelling with ACE inhibitors (anticholinergic effect)?
Definition
They end in –pril i.e…lisinopril
Term
What are some side effects of diuretics?
Definition
Diuretics are used for two main purposes: to decrease htn, and to decrease edema in heart failure and renal or liver disorders, they can cause hypotension, hypokalemia, hyponatremia, dehydration, ototoxicity and bradycardia
Term
What are some instructions you can advise the patient to do when taking Diuretics?
Definition
Instruct on increase and frequency of urination
Instruct to rise slowly from lying or sitting position
Instruct to protect skin from sun
Eat foods high in potassium
Check B/P, pulse before each dose
Term
What types of medications can mask symptoms of disease?
Definition
OTC.
Term
How long does St Johns Wart to become therapeutic?
Definition
therapeutic in 4-8 weeks.
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