Term
migraine headache
characteristics |
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Definition
- moderate to severe
- nausea & vomiting
- photophobia/phonophobia
- family hx
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Term
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Definition
migraine with aura
migraine without aura |
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Term
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Definition
aka migraine with aura
headache is preceded by visual symptoms (flashesof light, a blank area in the field of vision, zigzag patterns) |
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Term
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Definition
aka migraine without aura
more common affecting 70% of migraineurs |
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Term
| secondary to identifiable causes of headache |
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Definition
HTN
Hyperthyroidism
tumor
ENT infection |
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Term
HEADACHES
no identifiable cause |
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Definition
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Term
Migraine headache
pathophysiology |
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Definition
dilation of intracranial blood vessels
inflammation of intracranial blood vessels
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Term
migraine
non specific analgesic drugs used in
Abortive therapy |
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Definition
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Term
| migraine-specific ana;gesics used in abortive therapy |
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Definition
- ERGOTAMINE
-SUMATRIPTAN |
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Term
| drugs used on mild-moderate headache |
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Definition
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Term
| drugs used ib moderate-severe migraine headache |
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Definition
-migraine specific drugs
-opioid analgesics |
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Term
| ergotamine mechanism of action |
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Definition
| in cranial arteries, ergotamine acts directly to promote constriction and reduce the amplitude of pulsations. It also affects blood flow by depressing vasomotor center |
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Term
| therapeutic effects of ergotamine |
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Definition
use to stop ongoing migraine attack
use to tx cluster headache
should not be taken daily on a long term basis due to risk for dependency |
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Term
| Pharmakokinetics of Ergotamine |
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Definition
-oral
-sublingual
-rectal
-inhalation |
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Term
| adverse effects of ergotamine |
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Definition
nausea & vomiting
weakness in the legs
myalgia
numbness & tingling
angina-like pain
tachycardia and bradycardia |
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Term
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Definition
ergotism
OD can also cause ischemia secondary to constriction of peripheral arteries and arterioles;
extremities become cold, pale and numb, mm pain develops; gangrene may eventually result |
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Term
triptans
HIV meds
antifungals
erithromycin
grapefruit |
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Definition
| drug interactions with Ergotamine |
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Term
Sumatriptan (Imitrex)
MOA |
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Definition
causes Vasoconstriction
diminishes pervascular inflammation |
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Term
| Administration of Sumatriptan (Imitrex) |
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Definition
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Term
Adverse effects of
Sumatriptan (Imitrex) |
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Definition
chest symptoms
coronary vasospasm
teratogenesis |
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Term
drug interactions of Sumatriptan (Imitrex)
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Definition
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Term
| Contraindications of Sumatriptan (Imitrex) |
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Definition
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Term
3 types of symptoms of Schizoprenia
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Definition
positive symptoms
negative symptoms
cognitive symptoms |
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Term
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Definition
| can be viewed as an exageration or distortion of normal function |
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Term
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Definition
| loss or diminution of normal functions |
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Term
schizo
cognitive symptoms |
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Definition
| disordered thinking, reduce ability to focus attention and prominent learning and memory difficulties |
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Term
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Definition
delusions (fixed fall beliefs)
hallucinations |
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Term
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Definition
suspiciousness
poor anxiety management
diminished judgement, insight, motivation and capacity for self care |
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