| Term 
 | Definition 
 
        | Reflects the level of stimulus needed to create a painful sensation |  | 
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        | Term 
 | Definition 
 
        | Prescribed for the relief of pain |  | 
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        | Term 
 
        | Nonsteroidal anti-inflammatory drugs (NSAIDs) |  | Definition 
 
        | A class of analgesic medication that reduces pain, fever and inflammation. Since most episodes of back pain involve inflammation, NSAIDs such as ibuprofen and naproxen are often an effective treatment option. |  | 
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        | Term 
 | Definition 
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        | Term 
 | Definition 
 
        | An unusual sensor disturbance often involving neural supersensitivity. This pain is due to injury or disease of the peripheral or central nervous system. |  | 
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        | Term 
 | Definition 
 
        | Neurotransmitters that naturally suppress pain conduction. |  | 
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        | Term 
 | Definition 
 
        | Prescribed for moderate to severe pain |  | 
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        | Term 
 | Definition 
 
        | A psychological and physical dependence upon a substance beyond normal voluntary control, usually after prolonged use of the substance. |  | 
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        | Term 
 | Definition 
 
        | A decrease in blood pressure due to a change in position (i.e. from sitting to standing) |  | 
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        | Term 
 | Definition 
 
        | Caused by physical dependence. Include irritability, diaphoresis, restlessness, muscle twitching, and increase in pulse rate and blood pressure. |  | 
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        | Term 
 
        | Patient-controlled analgesia (PCA) |  | Definition 
 
        | An alternative route for opioid administration for self-administered pain relief as needed. |  | 
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        | Term 
 | Definition 
 
        | Nonopioids with or without adjuvant medication |  | 
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        | Term 
 | Definition 
 
        | Nonopioids and mild opioid with or without adjuvant medication |  | 
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        | Term 
 | Definition 
 
        | Stronger opioid at higher dosage leves with or without adjuvant medication |  | 
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        | Term 
 | Definition 
 
        | Drugs with a primary indication other than pain that have analgesic properties in some painful conditions. |  | 
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        | Term 
 
        | Opioid agonists-antagonists |  | Definition 
 
        | Medications in which an opioid antagonist (e.g., naloxone [Narcan]) is added to an opioid agonist. |  | 
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        | Term 
 | Definition 
 
        | Blocks the receptor and displaces an opioid that would normally be at the receptor, inhibiting the opioid action. |  | 
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        | Term 
 | Definition 
 
        | Characterized by a severe unilateral non-throbbing pain usually located around the eye. |  | 
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        | Term 
 
        | Drug class: analgesic Therapeutic effects/uses: decrease pain and fever
 Side effects: anorexia, nausea, vomiting, rash, insomnia
 Adverse reactions: elevated liver enzymes
 |  | Definition 
 
        | Prototype drug: Acetaminophen Drug class:
 Therapeutic effects/uses:
 Side effects:
 Adverse reactions:
 |  | 
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        | Term 
 
        | Drug class: opioid Therapeutic effects/uses: severe pain relief
 Side effects: anorexia, nausea, vomiting, constipation, drowsiness, dizziness, sedation, confusion, urinary retention, rash, blurred vision, bradycardia, flushing, euphoria
 Adverse reactions: Hypotension, seizures, respiratory depression
 |  | Definition 
 
        | Prototype drug: Morphine Sulfate Drug class:
 Therapeutic effects/uses:
 Side effects:
 Adverse reactions:
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