Term
| Hypnotics and the elderly |
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Definition
-2nd most common given to elderly
-can cause confusion, depression, anticholinegeric effects
-ex. Flurazepam HCL (Dalmane) |
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Term
| Cardiac glycosides and the elderly |
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Definition
-Narrow therapeutic range tolerated
-Bad because of decreased kidney function
-ex. digoxin |
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Term
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Definition
-hydrochlorothiazide
-causes in the elderly electrolyte imbalances, hyperglycemia, hyperuricemia, and hypercholesterima |
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Term
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Definition
| especially elderly are at risk for bleeding |
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Term
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Definition
| agent to which all other drugs in a class are compared to |
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Term
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Definition
| the breakdown of a tablet into smaller pieces |
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Term
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Definition
| the dissolving of the smaller particles in the GI fluid before absorption |
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Term
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Definition
| the time it takes the drug to disintegrate and dissolve to become available for the body to absorb it |
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Term
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Definition
| movement of the drug to the blood circulation |
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Term
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Definition
| movement of the drug through the bloodstream into body tissues into cells |
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Term
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Definition
| chemical conversion or transformation into compounds |
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Term
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Definition
-elimination of unchanged drug or metabolite
-source: renal, biliary, pulmonary, or skin |
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Term
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Definition
| large one time does to decrease the time required for a drug to reach its critical concentration |
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Term
| Where does absorption occur? |
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Definition
GI tract
Mucous membranes
skin
lungs
muscles or sub q tissues
IV |
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Term
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Definition
| the percentage of the administered drug dose that reaches the systemic circulation |
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Term
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Definition
| metabolic change of drug before it reaches the system circulation |
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Term
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Definition
| how much fat it has to get through before the drug can take effect |
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Term
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Definition
-biochemical and physical effects of drugs and the mechanisms of the drug actions
-anticipate therapeutic and adverse drug effects
-intervene in ways that assure the most effective drug regimen for the patient |
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Term
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Definition
| interaction at the cellular level between a drug and cellular components |
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Term
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Definition
-response that results from the drug action
-what action it takes once it gets in the body |
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Term
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Definition
1. Replace or act as substitutes for missing chemicals 2. Increase or stimulate certain cellular activities
3. Depress or slow cellular activities
4. Interfere with the functioning of foreign cells |
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Term
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Definition
-the study of the natural drug sources
-plants, animals, minerals, labs |
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Term
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Definition
-the study of the natural drug sources
-plants, animals, minerals, labs |
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