Term
| Treatment for primary pulmonary hypertension |
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Definition
Bosentan
competitively antagonist endothelial 1 receptors, which decrease pulmonary vascular resistance |
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Term
| Treatment for asthma: Blocks leukotriene receptors |
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Definition
Zafirlukast, Montelukast
Good for asprin induced asthma |
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Term
| Treatment for asthma: Inhaled long acting B2 agonist |
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Definition
Isoproterenol
Non-specific Beta agonist (Both B2=B1 effects). Results in smooth muscle relaxation and tachycardia |
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Term
| Treatment for asthma: Inhaled treatment that blocks muscarinic receptors |
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Definition
Ipratropium
Muscarinic Antagonist |
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Term
| Treatment for asthma: Inhibits mast cell release of mediators, used for prophylaxis only |
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Definition
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Term
| Treatment for asthma: Blocks conversions of arachadonic acid to leukotriene |
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Definition
Zileuton
A 5-lipoxygenase pathway inhibitor. Inhibits conversion of arachadonic acid to leukotrienes |
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Term
| Treatment for asthma: Narrow therapeutic index, last resort |
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Definition
Methylxanthine:
Theophylline
Blocks phosphodiesterase (enzyme used to degrade cAMP to AMP). Keeps levels of cAMP high in cell to stimulate response. |
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Term
| Treatment for asthma: Inhaled treatment of choice for acute exacerbations |
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Definition
Beta2 agonists:
Albuterol/Levalbuterol |
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Term
| Treatment for asthma: Inhaled treatment of choice for chronic asthma |
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Definition
Inhaled Corticosteroids:
Prednisone
Beclomethasone
Inactivates NF-kB, transcription factor to TNFalpha |
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Term
| Treatment for asthma: Reversible inhibitors of H1 Histamine receptors |
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Definition
1st generation H1 blockers:
Diphenhydramine
Dimenhydrinate
Chlorpheniramine
Used for allergy, motion sickness, sleep aid.
Toxcitiy: causes sedation, antimuscarinic and anti-alpha adrenergic. Enters into the CNS and can cause psychosis |
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Term
| Treatment for asthma: Reversible inhibitors of H1 histamine receptors (2nd generation) |
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Definition
2nd Generation H1 blockers:
Loratidine
Fexofenadine
desloratadine
cetirizine
Far less sedating than 1st generation |
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Term
| Drug treatment used as an expectorant (to cough up sputum) |
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Definition
Gauifenesin (mucinex)
Robitussin (Gauifenesin + dextromethorphan)
Gauifenesin removes excess sputum but does not suppress cough reflex.
Robitussin has cough suppressant |
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Term
| Treatment for cyanide poisoning causing cyanosis |
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Definition
Nitrates
Nitrates given to oxidize hemoglobin to methemoglobin.
Normally, Methemoglobin (caused from oxidized Hb) does not bind to O2 well, but does bind CN well. |
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