| Term 
 
        |   Heparin    -what it does   -what is it used for  |  | Definition 
 
        | Heparin prevents clots by causing prompt antigoagulant activity   Heparin is used for strokes, pulmonary embolisms, and massive DVT |  | 
        |  | 
        
        | Term 
 
        | Low molecular weight heparins..   2 medication names    What are they used for  |  | Definition 
 
        | Enoxaparin and Dalteparin    Low molecular weight heparins are used to treat DVT and prevent DVT post-op |  | 
        |  | 
        
        | Term 
 
        |   Heparin complications    normal    life threatening    what to monitor for  |  | Definition 
 
        |   normal- increased bleeding, heart rate, decreased BP   Life threatening- Hep induced Thrombocytopenia (HIT)  massive bleeding   watch for bruising, bleeding through mucous membranes, black tarry stools, low platelet counts, Petechiae |  | 
        |  | 
        
        | Term 
 
        |   Heparin antidote    Lab to monitor    Route of administration  |  | Definition 
 
        |   Protamine    monitor PTT   IV route only  |  | 
        |  | 
        
        | Term 
 
        |     Heparin contraindications  |  | Definition 
 
        |    contraindicated in low platelet counts  following eye, brain, spinal cord surgeries, lumbar puncture, or regional anesthesia  PUD, severe hypertension, liver or kidney disease    avoid NSAIDS and other anticoagulants  |  | 
        |  | 
        
        | Term 
 
        |   Heparin nursing administration  |  | Definition 
 
        |   Obtain baseline vitals, CBC, platelet count must check with another nurse  monitor PTT every 4-6 hours  sub Q (in stomach only) or IV do not aspirate  monitor for bleeding electric razor, soft toothbrush |  | 
        |  | 
        
        | Term 
 
        |   Oral anticoagulant    used to treat |  | Definition 
 
        | Warfarin    used to treat venous thrombosis, thrombus formation in A-fib  prevention of recurrent MI, ischemic attacks, PE, DVT |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   Hemorrhage  monitor vitals and for bleeding tell patients signs of bleeding  monitor PT and INR   |  | 
        |  | 
        
        | Term 
 
        |   Warfarin overdose    antidotes  |  | Definition 
 
        |   Administer Vitamin K  must be diluted and pushed slowly   If vitamin K doesn't work administer fresh frozen plasma or whole blood  |  | 
        |  | 
        
        | Term 
 
        |   Warfarin contraindications |  | Definition 
 
        | prganancy category X- fetal hemmorhage and death   no clients with low platelet counts ( thrombocytopenia) or current uncontrollable bleeding    recent eye or spinal cord surgeries, lumbar puncture, or regional anesthesia  Liver or alcohol disorders higher bleed risk |  | 
        |  | 
        
        | Term 
 
        | Warfarin interactions    drugs   foods   |  | Definition 
 
        | drugs: heparin, aspirin, acetaminophen all increase effects of warfarin   foods: high vitamin K foods  ie. lettuce, spinach, cabbacge, broccoli, leafy greens, mayo   if you already have diet high in Vit.K it is fine to continue but do not suddenly increase vit. K - decrease effects f warfarin  |  | 
        |  | 
        
        | Term 
 
        |   warfarin nursing administration   route    key actions |  | Definition 
 
        | route is usually always oral obtain vitals  monitor PT and INR (most accurate)  baseline CBC, Platelets, HCt full effect is not achieved for 3-5 days may be on heparin until then  avoid alcohol and OTC medication, wear med alert bracelet bleeding precaustions, toothbrush and razor |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   administer vitamin K to increase clotting factor    |  | 
        |  | 
        
        | Term 
 
        |   Direct thrombin inhibitors    Main drug    other drugs end in?   how does it work? |  | Definition 
 
        | Dabigatron    other drugs end in "rudin"   works by directly inhibiting thrombin thereby, preventing thrombus from being formed    |  | 
        |  | 
        
        | Term 
 
        | Dabigatron (rudin)   pharmacological use     |  | Definition 
 
        |   prevents stroke or embolism in client who have A-fib |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   used to prevent or treat thrombosis in clients who can not take heparin due to HIT heparin induced Thrombocytopenia  |  | 
        |  | 
        
        | Term 
 
        |   direct thrombin inhibitor complications    antidote  |  | Definition 
 
        | GI bleeding, ulcer formation, nausea,vomitting  - take with food to reduce risk      Dabigatron has no antidote    contraindicated in active bleeding and liver impairement  |  | 
        |  | 
        
        | Term 
 
        |     direct thrombin inhibitor nursing actions |  | Definition 
 
        |   oral capsules    prefered without food for absorbtion but can be take with food to reduce GI effects    must be used within 30 days of open container  |  | 
        |  | 
        
        | Term 
 
        | Direct inhibitor of factor Xa   drug    theraputic uses |  | Definition 
 
        |   Rivaroxaban    ued in clients who have atrial fibrilation and in the prevention of DVT and PE  |  | 
        |  | 
        
        | Term 
 
        | Direct inhibitor of factor Xa   complications    antidote    interactions  |  | Definition 
 
        | Rivaroxaban can cause bleeding, GI effects  teach client how to minotr bleeding and what to report   no antidote can give activated charcoal to prevent further absorption   Interact with Erythromycin, Diltiazem, Verapamil, amioderone |  | 
        |  | 
        
        | Term 
 
        | Direct inhibitor of factor Xa   Key nursing actions  |  | Definition 
 
        | monitor liver function and kidney function moitor base line function and test periodically    monitor HGB and HCT    use cautiously with multiple anticoagulants    oral med with food  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   Aspirin (salicyclic)   Clopidegrel   Pentoxyfylline   Cilostazol |  | 
        |  | 
        
        | Term 
 
        |   antiplatelets    which two can be given together   |  | Definition 
 | 
        |  | 
        
        | Term 
 
        |   antiplatelets    MOA   theraputic uses   route  |  | Definition 
 
        |   prevents platelets from clumping together  inhibit platelet aggragation   Used to prevent MI aspirin 81mg/day ischemic sroke, acute coronary syndrome    oral route  |  | 
        |  | 
        
        | Term 
 
        | antiplatelets    complications    what to monitor for  |  | Definition 
 
        |   complications include GI effects, tinnitus- reyes syndrome  bleeding dizziness, weakness, headache    monitor for bruising, black tarry stools, bleeding gums, coffee ground emesis, ringing ears  |  | 
        |  | 
        
        | Term 
 
        |   Thrombolytic medications    main drug   drugs end in    when to use the drug  |  | Definition 
 
        |   Alteplase  "plase" drugs    clot busters dissolve an active clot if used within 30 mins of formation  |  | 
        |  | 
        
        | Term 
 
        | Alteplase    used for    special precaution |  | Definition 
 
        |   used to treat acute myocardial infarction      limit sites of venipuncture and injections    |  | 
        |  | 
        
        | Term 
 
        |   Alteplase    contraindications   interactions  |  | Definition 
 
        | contraindicated in any prior hemorrhages, cerebral vascular lesions, active internal bleeding, history of head or spinal trauma past 2 months, brain tumors, liver or kidney disorder. recent GI bleeding, major surgery w/in 10 days, older clients   Interacts with NSAIDS, heparin, warfarin, thrombolytics, antiplatelets  |  | 
        |  | 
        
        | Term 
 
        |   Alteplase    nursing administrations   labs to check  |  | Definition 
 
        | Use of thrombolyitics should be used within 3 hours of clot   obtain baseline vitals  platelets, HGB, HCT, aPTT, PT, INR    ensure adquate IV access for emergency medications and have emergency equipment available  limit iv puncture sites  |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        |   Whole Blood   -what does it do   -when is it given  |  | Definition 
 
        |   Whole blood increases the total amount of circulating blood volume      whole blod is only given in traumatic injuries r surgicl procedures... significant blood loss     |  | 
        |  | 
        
        | Term 
 
        |   Packed Red Blood Cells (PRBCs)   what they do   when are they used  |  | Definition 
 
        |   packed rbc's increase only the rbc count   this is needed in severe symptomatic anemia rbc's carry oxygen  |  | 
        |  | 
        
        | Term 
 
        |   Platelet concentrate   what does it do   theraputic uses  |  | Definition 
 
        |   increases platelet count    used for thrombocytopenia  platelets less than 20,000   active bleedig less than 50,000 |  | 
        |  | 
        
        | Term 
 
        |     Fresh Frozen plasma    what does it do theraputic uses  |  | Definition 
 
        |   replaces coagulation factors    used in excessive bleeding massive hemorrhage  exstensive burns  |  | 
        |  | 
        
        | Term 
 
        |   Albumin   what does it do    theraputic uses  |  | Definition 
 
        |   expands circulating blood volume    theraputic uses  burns and hypoalbuminemia |  | 
        |  | 
        
        | Term 
 
        | Blood product complications    Acute Hemolytic Reactions:   what it is  symptoms when it occurs  what to do  |  | Definition 
 
        | Reaction to the wrong blood type  very deadily will destroy all blood cells save tubing send to lab   Assess basline vitals  stay during the intial 15 mis will happen very early  stop infusion immediately! keep IV open with saline  |  | 
        |  | 
        
        | Term 
 
        | Blood product complications    Febrile nonhemolytic reactions  |  | Definition 
 
        |   most common reaction   save tubing send to lab   fever (any increase in temperature from baseline)   sudden chills    administer acetaminophen for fever  |  | 
        |  | 
        
        | Term 
 
        | Blood product complications   Anaphylactic reactions    signs and symptoms what you do  antidote  |  | Definition 
 
        | Symptoms- anxiety wheezing SOB shock cardic arrest   what do you do- stop infusion save tubing send to lab  notify provider keep iv open with saline    administer epinepherine  |  | 
        |  | 
        
        | Term 
 
        |   Blood product complications   Circulatory overload:   what it is whos at risk- symptoms what to do    |  | Definition 
 
        | Excess fluid volume  older adults are at a higher risk  and clients who have high infusion unit amounts   symptoms- coughing, SOB, crackles, hypertension, tachycardia, jugular veins    stop infusion, administer diuretics, and oxygen monitor I/O |  | 
        |  | 
        
        | Term 
 
        | Blood product complications   Sepsis   what to monitor for symptoms  what to do  treatment  |  | Definition 
 
        | monitor blood product for gas bubbles  discoloration and cloudiness   symptoms rapid onset of chills fever vomitting diarrhea shock hypotension   Obtain blood culture, send the tubing blood to lab for analysis.  Treat with antibiotics and steroids  |  | 
        |  | 
        
        | Term 
 
        |   Blood Product nursing administrations   key points |  | Definition 
 
        |   Obtain baseline values HGB, HCT, Platelets, protien levels, albumin, PT, PTT, fibrogen, potassium, calcium  - ensure 20-gauge or larger IV for blood cells - full transfusion should be done within 4 hours from fridge - always use 0.9% normal saline  - change tubing every 2 units of blood to prevent infection - blood must be in it's own line not with any other meds  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Greater or equal amounts of blood volume being replaced that are in the body.    normally 10 units of blood  or 5 units in 4 hours monitor PT PTT Platelets every 5 units  monitor potassium and calcium  warm blood using blood warmer to prevent hypothermia |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        |     moving blood clot   to brain or lungs  |  | 
        |  | 
        
        | Term 
 
        |   Peptic Ulcer disease      What is it  |  | Definition 
 
        |   The imbalance between gastric mucosal defenses and antagonistic defenses    Acid becomes too high and breaks down mucosal defense |  | 
        |  | 
        
        | Term 
 
        |   Peptic Ulcer disease    Medications  |  | Definition 
 
        | Antibiotics    Amoxicillin Clarithromycin Metronidazole Tetracycline   |  | 
        |  | 
        
        | Term 
 
        |   Peptic Ulcer disease    how do the antibiotics work |  | Definition 
 
        |   alters and stops the disease process    eradication of H. Pylori bacteria  |  | 
        |  | 
        
        | Term 
 
        |   Peptic Ulcer disease    how do you know it is H.Pylori/ how is it treated  |  | Definition 
 
        |   H.Pylori is always treated with 2-3 antibiotics for 14 days to increase the effectiveness and minimize resistance   never suddenly stop antibiotics suddenly  |  | 
        |  | 
        
        | Term 
 
        |   H2 Receptor antagonists    Main med   all meds end in |  | Definition 
 | 
        |  | 
        
        | Term 
 
        |   H2 Receptor antagonists Rantidine    how it works  |  | Definition 
 
        |     lowers acid acid concentration in the stomach |  | 
        |  | 
        
        | Term 
 
        |   Cimetidine    -when is it used    -Sde Effects |  | Definition 
 
        |   hardly used anymore because it causes many adverse side effects    side effects are decreased libido, gynecomastia, impotence   can inhibit medication metabolizing in warfarin theophylline lidocaine  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |     have almost no side effects  used to decrease gastric acid and ulcers   caution in elderly (can cause CNS effects) caution in pneumonia and COPD monitor WBC |  | 
        |  | 
        
        | Term 
 
        |   H2 receptor antagonists    nursing actions  |  | Definition 
 
        |    tell client to avoid foods that promote gastric acid secretion such as caffiene decaf and caf    tell clients to avoid NSAIDS   encourage to always call provider if any questions or problems even though meds are OTC talk to pharmacist |  | 
        |  | 
        
        | Term 
 
        |   proton pump inhibitors   drugs end in  |  | Definition 
 | 
        |  | 
        
        | Term 
 
        |   proton pump inhibitors   how do they work   theraputic effects  |  | Definition 
 
        | prazoles work by reducing acid production   ulcers, erosive esophagitis, GERD, hyper acid syndrome |  | 
        |  | 
        
        | Term 
 
        |   proton pump inhibitors   complications    contraindications    interactions  |  | Definition 
 
        | prazoles  headache diarrhea nausea vomitting  osteoperosis long term use - take Vit D an calcium contraindicacted in clients who have dysphagia or liver disease, COPD, osteoperosis    Prazoles and azoles do not mix Digoxin levels increase- monitor levels |  | 
        |  | 
        
        | Term 
 
        |     proton pump inhibitors   nursing administration |  | Definition 
 
        | do not crush chew or sprinkle over food   take once a day in morning prior to food   avoid NSAIDS and alcohol    treat ulcers for 4-6 weeks   watch for bleeding  |  | 
        |  | 
        
        | Term 
 
        |   Mucosal Protectant    drug   what does it do    times to administer  |  | Definition 
 
        | sucralfate    form protective barrier over ulcers  can protect ulcer for 6 hours   take an hour before meals 3x a day and bedtime    |  | 
        |  | 
        
        | Term 
 
        | Mucosal Protectant sucralfate    side effects  contraindications interactions  nursing administration    |  | Definition 
 
        | no systemic side effects, may cause constipation   contraindicated in kidney disease and failure    interfere and lessen absorption of warfarin digoxin give 2 hours apart   take 4x a day an hour before meals and bedtime |  | 
        |  | 
        
        | Term 
 
        | Antacids    how does it work/ what is it used for   3 drugs    |  | Definition 
 
        |   antacids nuetralize gastric acid and inactivate pepcin to reduce pain. Does not cure just relieves pain in GERD   Aluminum hydroxide Magnesium hydroxide Calcium carbonate      |  | 
        |  | 
        
        | Term 
 
        | Antacids that cause constipation   2 drugs  |  | Definition 
 | 
        |  | 
        
        | Term 
 
        |   what does the calcium compound cause  |  | Definition 
 | 
        |  | 
        
        | Term 
 
        |     drug that causes diarrhea  |  | Definition 
 | 
        |  | 
        
        | Term 
 
        |   two antacids that can be combined    when are they combined  |  | Definition 
 
        |   aluminum and magnesium    combined when a client has trouble controlling their bowel functions  |  | 
        |  | 
        
        | Term 
 
        |   antacids   side effects    contraindications      |  | Definition 
 
        | fluid retention in antacids containing sodium- keep away from hypertensive patients ad heart failure   magnesium compounds can lead to toxicity and should be avoided in renal failure    never take antacids with alcohol or GI obstructions  |  | 
        |  | 
        
        | Term 
 
        |   antacids    nursing administration |  | Definition 
 
        |   shake all liquid formulations to evenly disperse medication   medication can be administered 7x daily  1 hour after each meal 3 hours after each meal and take before bedtime  take all other meds an hour apart from antacids  |  | 
        |  | 
        
        | Term 
 
        |   Prostaglandin E   drug    when is it used/ what is it for |  | Definition 
 
        | Misoprostol    used for prevention of ulcers in long term NSAID use    used to induce labor in pregnant  |  | 
        |  | 
        
        | Term 
 
        |   Misoprostol    side effects    contraindications  |  | Definition 
 
        |   diarrhea, dysmennorrhea is normal   contraindicated in pregnancy |  | 
        |  | 
        
        | Term 
 
        |   Gastrointestinal Disorders    Antiemetics    used for  |  | Definition 
 
        |   CINV  cancer induced nausea and vommitting    anti nausea |  | 
        |  | 
        
        | Term 
 
        | Antiemetics    Dexamethasone |  | Definition 
 
        |   CINV  glucocorticoid  raises blood sugar, increases infection long term cushings disease- moon face buffalo hump  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   post op drug for nausea    common drug dizziness headache diarrhea    CINV   don't give if they have long QT intervals |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   must be diulted and administered through central vein    Side effects sedation hypotension anticholergenic effect    EPS- face spasms discontinue immediatly    antidote- diphenhydramine or bensatropine |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   treat CINV increase appetite    decrease BP increase HR   cannibas related side effects  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   scopolamine    treats motion sickness  transdermal administration    anticholinergic  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |     high rates of sedation   depress nerve function at multiple CNS sites  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   Psyllium docusate  bisacodyl magnesium  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   bulk forming laxative softens fecal mass and increases bulk  identical to dietary fiber    control stool for ileostomy or colostomy    promotes defecation in older adults  |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   used for opioid costipation   stool softener doesnt makeyou go just makes it easier   relieves constipation less painful bowel movements |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   will make you run! will make you go!   used prior to surgeries or testing like colonoscopy |  | 
        |  | 
        
        | Term 
 
        | Laxatives    magnesium hydroxide  |  | Definition 
 
        |   draws water in to intestine    used for post op client prep  rapid evacuation of bowels gives you the runs    can lead to magnesium toxicity avoid in kidney function |  | 
        |  | 
        
        | Term 
 
        |   Laxatives    contraindications   nursing administrations |  | Definition 
 
        | contraindicated in clients with bowel obstruction avoid ulcerative collitis and diverticulitis   teach that laxatives can lead to fluid and electrolyte imbalance   increase fluid amounts 2-3L per day encourage exercise  |  | 
        |  | 
        
        | Term 
 
        |   Antidiarrheals    Diphenoxylate  |  | Definition 
 
        | will effect CNS at high doses Decrease intestinal motility in opiod receptors anticholergenic effects  provide symptomatic relief to diarrhea    contraindicated i GI issues and blocks avoid alcohol and depressants  tell clients to avoid caffiene and not to drink plain water but refuel electrolytes  |  | 
        |  | 
        
        | Term 
 
        |   prokinetic agents   Metroclopramide |  | Definition 
 
        | good for post op nausea and vomitting  may cause NARCS-U side effects  increases upper GI motility  CINV control and GERD management  may cause sedation and EPS contraindicated in seizures and GI Issues  no alcohol or depressants  |  | 
        |  | 
        
        | Term 
 
        | IBS-D   drug whos it for side effects cintraindications nursing administrations |  | Definition 
 
        | Alosetron only for women for diarrhea lasting 6months with resistance to first line medications can result in GI toxicity bowel obstruction and perforation   contraindicated on bowel issues, chrons, bowel obstructions clients issues should resolve within 4 weeks but will reutrn a week following dicontinuation  |  | 
        |  | 
        
        | Term 
 
        | IBS-C   drug action  complications   |  | Definition 
 
        | Lubiprostone   increases fluid secretion- causes diarrhea   used for chronic constipation   may cause severe diarrhea monitor stools and loss of fluid and elctrolytes  |  | 
        |  | 
        
        | Term 
 
        | Sulfasalazine    use   complications    contraindications |  | Definition 
 
        | used for IBS, crohns, IBD   can cause anemia monitor CBC levels may cause nausea and vomitting   contrindicated in pregnancy |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   various bacteria and yeast and normal flora   used to treat and prevent C.difficile and diarrhea    may cause bloating and gas   administer 2hrs apart from antibiotics  |  | 
        |  | 
        
        | Term 
 
        |   Insulin    pharmacological action   complications  |  | Definition 
 
        |   promotes cellular uptake of glucose - decreases levels moves potassium into cells treatment of hyperkalemia, extreme stress and infection     complications are hypoglycemia- too much insulin  cold and clammy need candy glucose  |  | 
        |  | 
        
        | Term 
 
        | Insulin   what is lipohypertrophy  |  | Definition 
 
        |   roatate injection sites and keep an inch between injection site  |  | 
        |  | 
        
        | Term 
 
        | Insulin interactions   Nursng administration |  | Definition 
 
        | concurrent use of diuretics and glucocorticoids can raise blood sugar levels    beta blockers can mask the SE of hypoglycemia    Short acting insulin clear long is cloudy ensure glucose is near when admin insulin role vial between hands rotate sites sub Q |  | 
        |  | 
        
        | Term 
 
        |   Insulin expiration   -unopened insulin -pre mixed insulin vials -premixed insulin syringes -vial in use  |  | Definition 
 
        | - unopened until expiration date in fridge   -premixed vial in fridge 3 weeks   -premixed syringe 1-2 weeks fridge   -in use room temp away from light and heat 1 month |  | 
        |  | 
        
        | Term 
 
        |   insulins that are clear in color, not administered IV, should never be mixed with another insulin  |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        |   Glipizide    oral antidiabetic |  | 
        |  | 
        
        | Term 
 
        | Glipizide    how does it work    type of diabetes   side effects |  | Definition 
 
        | releases insulin from the pancreas    type 2 diabetic blood glucose control with diet and exercise   may caue hypoglycemia give snack 15g carbs 4oz of orange or 2 oz grape juice  8oz of milk |  | 
        |  | 
        
        | Term 
 
        | Glipizide      key interactions   nursing admnistrations |  | Definition 
 
        | take with breakfast   Use with alcohol can cause a disulfiram reaction   NSAIDS can cause added hypoglycemic effects    beta blcokers can mask hypoglycemic signs ad inhibit insulin release  |  | 
        |  | 
        
        | Term 
 
        |   Biguanides  oral antidiabetic   medication |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Metformin     how does it work  |  | Definition 
 
        |   reduces the production of glucose in the liver by suppresing gluconeogenesis   first line medication for type 2 diabetes  |  | 
        |  | 
        
        | Term 
 
        | Metformin   side effects   life threatening side effects |  | Definition 
 
        | may cause hypoglycemia administer snack 15g or grape 2oz orange 4oz milk 8oz   Gastrointestinal effects minor and go away over time    Life threatening lactic adidosis stop medication- shown by hyperventilation myalgia    |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | always discontinue 48 hours before testing with dyes start med back 48 hours followng testing    iodine concurrent use results in kidney failure   take med 2x daily with food  |  | 
        |  | 
        
        | Term 
 
        |   Acarbose   how does it work   side effects   how to take |  | Definition 
 
        | slows carbohydrate absorption    side effects are GI discomfort  Hepatotoxicity long term get basline liver function and periodic monitoring use with metformin adds to GI effects  must take with the first bite of food 3x daily  |  | 
        |  | 
        
        | Term 
 
        |   Levothyroxine    used for interractions side effects  contraindictions |  | Definition 
 
        | Hypothyroidism   Drug increases metabolic rate  may decrease digoixn levels  overmedication may cause hyperthyroidism symptoms  Chronic over treatment may cause A-fib Contraindicated in MI, cardiovasular disease adrenal insufficiency  |  | 
        |  | 
        
        | Term 
 
        | Propylthiouracil (PTU)    used for interractions side effects  contraindictions |  | Definition 
 
        | used for hyperthyroidism creates euthyroid state too much can cause hypothyroidism  contraindicated in clients with bone marrow or immune suppresion and liver failure  interacts with Digoxin and anticoagulants |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   anxiety, tachycardia, palpitations, altered appetite, Abdominal cramping, heat intolerace, fever, rapid weight loss, menstrual irregularities |  | 
        |  | 
        
        | Term 
 | Definition 
 
        |   Drowsiness, depression, weight gain, edema, bradycardia, anorexia, cold intolerance, dry skin |  | 
        |  | 
        
        | Term 
 
        |   Thyroid disorder umbrella points   -interactions  -evaluation of effectiveness -key nursing points  |  | Definition 
 
        | thyroid drugs interact with Digoxin levels, and cause greater bleeding risk in anticoagulants. Drugs must be continued during pregnancy and provider must be notified to switch drug brands. effectiveness will create euthyroid state and subside symptoms  monitor vitals weight I/O CBC T3 T4 Instruct that medication is LIFELONG- do not discontinue |  | 
        |  | 
        
        | Term 
 
        |   Radioactive Iodine    what does it do |  | Definition 
 
        | Treat hyperthyroidism and throid cancer in clients who have not responded to any other treatment options   will destroy thyroid  |  | 
        |  | 
        
        | Term 
 
        |     Radioactive Iodine    complications    contraindications |  | Definition 
 
        | complications- radiation sickness, nausea vomitting bone marrow supression hypothyroidism    Contraindications- Pregnancy X must test for pregnanacy before administering medication  discontinue all other antithyroid medications 1 week prior |  | 
        |  | 
        
        | Term 
 
        |     Radioactive Iodine    nursing administration  teaching points  |  | Definition 
 
        | client must remain 6 feet from others  do not share their utensils limit contact to 30mins per day per person increase fluid intake dispose of waste per biohazard protocol viod frequently  keep secretions away from others  |  | 
        |  | 
        
        | Term 
 
        |     nonradioactive Iodine    used for complications interactions |  | Definition 
 
        | used to create euthyroid state and decrease thyroid size prior to surgical removal   may cause iodism - early toxicity metallic tast rash frontal headache sore teeth and gums   Interact with iodine enriched food, stay away from seafood  |  | 
        |  | 
        
        | Term 
 
        |   nonradioactive Iodine      nursing administration |  | Definition 
 
        |   May be take in conjunction with another therapy, does not interact dilute iodine with juice to improve taste take same time daily  increase fluid intake  do not discontinue medication |  | 
        |  | 
        
        | Term 
 
        |   Antidiuretic hormone   medications |  | Definition 
 
        |   Vasopressin    Desmopressin (synthetic form) |  | 
        |  | 
        
        | Term 
 
        |   Vasopressin    what is it    what it does    what it is used for  |  | Definition 
 
        | ADH hormone  promotes reabsorption of water in kidneys  causes vasoconstriction   used to treat diabetes insipidus (large excretion of water) sometimes used during CPR to increase blood flow to brain and heart  |  | 
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        | Vasopressin    complications    contraindications   nursing administration  |  | Definition 
 
        | complications are too much water absorption, pounding headache change in LOC Excessive vasoconstriction - myocardial ischemia   contraindicated in MI Coronary artery disease, renal impairments    Monitor vitals, EKG BP BUN Creatnine I/O Electrolytes |  | 
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        |   Hydrocortisone    how does it work   what is it used for |  | Definition 
 
        | works my mimicking the effect of natural steriod hormones.   Used for chronic and acute replacement therapy for adrenalcortical insufficiency    |  | 
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        | Hydrocortisone      complications      contraindications |  | Definition 
 
        | complications- Osetoporosis long term use, adrenal suppression taper off, PUD- monitor for bleeding, Infetion, retention of fluid and sodium.    contraindicated in clients with active infection, monitor closely with diabetes, hypertension, heart failure, hypokalemia |  | 
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        | Hydrocortisone      interactions   Nursing administration |  | Definition 
 
        |   interacts with NSAIDS, acetaminophen, alcohol   do not give with live accines will get infection   give med with food orally, taper dose off do not stop suddenly, notify provider if fever, muscle pain, weakness |  | 
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        | what is important to remember about thrombolytic medication   what is the drug name  |  | Definition 
 
        |   Alteplase   can cause a alot of bleeding very quickly, monitor your sites of injection and limit them  |  | 
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        |   What 2 drugs are most hospital patients on as a preventative |  | Definition 
 
        |   pantoprazole- to prevent stress ulcers when in high stress environment    Enoxaparin- prevent clots in bed ridden patients |  | 
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        | Term 
 
        |   Iron supplements    drug    key facts  |  | Definition 
 
        | Ferrous Sulfate    treat and prevent iron deficiency anemia May cause GI effects potant stain teeth must dilute with orange juice  IV form may stain skin se Z-track IV route is safer than parenteral  may cause tarry stools that are not bleeding! |  | 
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        |   Vitamin B12   what is it called   Key points |  | Definition 
 
        | Cyanocobalamin   necessary to convert folic acid into active form b12 anemia may cause heart dysrhythmias  loss of intrinsic factor canot take oral monitor potassium, cannot just treat folic acid   B12 deficiency- beefy tounge pallor neuropathy |  | 
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        |   conducts nerve impulses may cause GI distress  may give insulin for overdose never administer bolus must push slowly  monitor I/O ange 3.5-5  |  | 
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        |   what goes first magnesium or potassium |  | Definition 
 
        |   Magnesium before Potassium! |  | 
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        |   
| -Lispro insulin (Humalog) -Insulin aspart (NovoLog) |      -Insulin glulisine (Apidra) |  | 
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        | O 15-30 mins P 0.5-2.5 hrs
 D 3-6hrs
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        |   
| -Regular insulin (Humulin R) |  
 
 
 (Novolin R) |  | 
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        |   O 0.5-1 hour P 1-5 hours D 6-10 hours |  | 
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        |   Intermediate insulin   names  |  | Definition 
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        |   O 1-2 hours P 6-14 hours D 16-24hours |  | 
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| -Insulin glargine (Lantus)  |   -Insulin detemir (Levemir) |  | 
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        | O 70 mins P noneD 24hours
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        | LAB VALUES   PT   NEW NORMAL PT |  | Definition 
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        |   LAB VALUES     aPTT aPTT NEW NORMAL |  | Definition 
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        |   LAB VALUES   INR NEW NORMAL INR |  | Definition 
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        |   LAB VALUES   HGB   MEN / WOMEN |  | Definition 
 
        |   MEN 13-17.3   WOMEN 11.5-15.5 |  | 
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        |   LAB VALUES   SERUM CHOLESTEROL |  | Definition 
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