Term
|
Definition
Diazepam
Estazolam
Flurazepam
Quazepam
Triazolam
Flumazenil (competitive antagonist of benzo site.) |
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Term
| Side Effects of Benzodiazepines |
|
Definition
-Drowsiness and ataxia
-Residual "Hangover" effects.
-Paradoxical hostility or irritability and rebound anxiety if quickly discontinued.
-Anterograde Amnesia (esp. events following dosage.)
**Can reduce RR if COPD or.... w/other CNS depressants, such as Alcohol. |
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Term
| Withdrawal effects of Benzodiazepines |
|
Definition
Insomnia, irritability.
esp if used > 4 mo.
esp. if stopped suddenly. |
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Term
|
Definition
| Anxiety, alcohol withdrawal, pre op sedation, mm spasm. (slow elimination) |
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Term
|
Definition
Anxiety, insomnia
(No residual sedation next day 40 hour half life!) |
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Term
|
Definition
Anxiety, insomnia
(decr sleep latency, and number of waking for insomnia)
Short acting ones reduce next day sedation |
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Term
|
Definition
Cause generalized non specific CNS depression.
'--Enhances GABA activity and directly opens Cl- channel.
May also lead to inhibitory NT release.
Low Dose: Depress sensory f'cn... Anti convulsant, sedation w/o analgesia or drowsiness.
High Dose:
Depress motor function, then medually centers (circulation and respiration) |
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