Term
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Definition
| a group of symptoms involving motor movements |
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Term
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Definition
| the most common form of parkinsonism |
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Term
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Definition
| used to treat the symptoms associated with parkinsonism |
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Term
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Definition
| drugs that either supplement the dopamine in the brain or block excess acetylcholine so that better transmission of nerve impulses occurs. |
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Term
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Definition
| drugs that affect the dopamine conted of the brain |
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Term
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Definition
| a meshwork of tightly packed cells in the walls of the brain's capillaries that screen out certain substances. |
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Term
| Dopaminergic drugs treat? |
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Definition
| Parkinson's disease, Parkinson-like symptoms(extrapyramidal), Restless leg syndrome, and viral infections (amantadine) |
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Term
| Adverse Reactions to Dopaminergic drugs are? |
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Definition
| Dry mouth and difficulty in swallowing, Increased had tremor. |
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Term
| The most serious adverse reaction with levodopa is? |
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Definition
| choreiform movements (involuntary muscular twitching of the limbs or facial muscles) |
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Term
| The least common but also serious reaction with levodopa is? |
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Definition
| mental changes: dementia, depression, psychotic episodes, paranoia, and suicidal tendencies |
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Term
| Levodopa is contraindicated in patients with? |
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Definition
| Narrow-angle glaucoma and those receiving MAOI antidepressants. |
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Term
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Definition
| MAOIs, selegiline and rasagiline should not be used with the opioid meperidine. |
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Term
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Definition
| Foods high in ___________ should be eaten in moderation. |
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Term
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Definition
| Drugs with cholinergic blocking activity block ACh in the CNS, enhancing _________. |
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Term
| diphenhydramine (Benadryl) |
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Definition
| _____________ are used in elderly patients, because they produce fewer adverse effects. |
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Term
| cholinergic blocking drugs (anticholinergics) |
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Definition
| used as adjunctive therapy in all forms of parkinsonism and in the control of drug-induced extrapyramidal disorders. |
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Term
| anticholinergics adverse reactions |
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Definition
| dry mouth, blurred vision, dizziness, mild nausea and nervousness, skin rash, urticaria (hives), urinary retention, dysuria, tachycardia, muscle weakness, disorientation and confusion. |
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Term
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Definition
| Patients ______yrs or older frequently develop increased sensitivity to anticholinergics and require careful monitoring. |
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Term
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Definition
| failure of the muscles of the lower esophagus to relax, causing difficulty swallowing. |
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Term
| anticohlenergic precautions |
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Definition
| patientws with tachycardia, cardiac arrhythmias, hypertension or hypotension, urinary retention and decreased liver or kidney functions. |
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Term
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Definition
| entacapone (Comtan) and tolcapone (Tasmar) |
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Term
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Definition
| ____________ increase the plasma concentrations and duration of action of levodopa. |
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Term
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Definition
| ______ are used as adjuncts to levodop/carbidopa in treating Parkinson's disease. |
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Term
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Definition
| Dyskinesias, hyperkinesia, nausea, anorexia and diarrhea, somnolence and muscle cramps are adverse reactions to ________? |
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Term
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Definition
| _________ is a contraindicated in patients with liver dysfunction. |
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Term
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Definition
| taking __________ with COMT inhibitors increases risk of toxicity of both drugs. |
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Term
| Dopamine receptor agonists |
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Definition
| ________ such as pramipexole (Mirapex)is used for the treatment of the s/s of Parkinson's disease. |
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Term
| Dopamine receptor agonists |
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Definition
| N/V, dizziness, somnolence, hallucinations, confusion, visual disturbances, postural hypotension, abnormal involuntary movements and headaches are the most common adverse reactions to ___________. |
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Term
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Definition
| ____________ includes observation of tremors of the hands and head while at rest. Masklike facial expressions. changes in walking. Muscular rigidity, drooling, difficulty in chewing or swallowing. |
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Term
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Definition
| __________ may exacerbate mental symptoms and precipitate a psychotic event. |
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Term
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Definition
| the nurse would ________ if the occurrence of choreiform and dystonic movements occur. |
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Term
| every 2 wks the first year then every 8 wks thereafter. |
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Definition
| regular blood testing to monitor liver function when taking tolcapone is usually done how often? |
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Term
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Definition
| a serious and potentially fatal adverse reaction to tolcapone is _______? |
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Term
| blurred vision and diplopia |
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Definition
| _______ and _______ are evidence by the patient's sudden refusal to read or watch television or by bumping into objects when ambulating. |
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Term
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Definition
| _________occur more often in the older adult than in the younger adult receiving antiparkinsonism drugs. |
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Term
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Definition
| How long is a drug holiday? |
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Term
| neuroleptic malignant-like syndrome |
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Definition
| ________ may occur when antiparkinsonism drugs are discontinued or the dosage of levodopa is reduced abruptly. |
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Term
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Definition
| what would one thing you would want to tell your patient's family members to remove from the home to decrease falls? |
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