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PHarmacology Exam #4 - Carters
Carters setion of drugs fro pharm exam #4
31
Other
Graduate
04/05/2009

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Term
Internal Hordeolum
Definition
Staphlococcal infection
Dicloxacillin
Cephalexin
Erythromycin - Very safe, prego cat A, safe for kids
Term
Preseptal Cellulitis
Definition
Staph, Strep, H. Influenzae Infection
Amoxicillin/Clavulanate-can use in kids
Others: Dicloxacillin, cephalexin, cefuroxine, ceftraxone, and cefotaxime
Term
Acute Dacryocystitis
Definition
Staph, Strep, and H Influenzae infections (more common in kids following birth trauma)
Dicloxacillin or Cephalexin - Adults
Amoxicillin/Clavulanate - Kids
Term
Meibomianitis/Acne Rosacea
Definition
Causes Dry Eye
Tetracyline
Doxycycline
Both drugs make sensitive to UV, can result in rash
Term
Chlamydial(adult inclusion) conjuntivitis or Trachoma
Definition
Env organism not sex transmission, can get papillae and follicle formation
Affect upperlid worst
Doxycycline
Tetracycline
Erythromycin-very effective, used when allergic to others
Azithromycin-long acting, can cure with one dose
Term
Gonococcal(adult) Conjunctivitis
Definition
Ceftriaxone
Term
Herpes Zoster Ophthalmicus
Definition
AKA shingles, stops at midline
Acyclovir-short T1/2
Valacyclovir-longer T1/2
Famciclovir-also longer T1/2
Very SElective, little aDR
CI hypersensitivitys
Term
Posterior Segment Infections
Definition
OD can only tx glaucoma
Toxoplasmosis-combo of Triple Sulfa, pyrimethamine, clindamycin, and prednisone
Toxocara Canis-worms from cat/dogs
CMV Retinopathy-Ganiciclovir-Iv, oral, injected
Term
Pain Management Guidelines
Definition
1. Tx underlying condition
2. Use symptoms as guide
3. Pretreatment History
4. KISS method
5. Dose regimen-Tx round the clock
6. Oral route for simplicity
7. OTC to dec cost if possible
8. Narcotic if needed
9. Adjuvant to help: cold compresses, caffeine,antihistamine, antidepressant
Term
Non-Narcotic Pain Management
Definition
Acetaminophen-doesnt dec amount of pain impulses but how CNS reacts to pain
ADR:Liver Toxicity
Aspirin:
ADR:upset GI, inc clott time, Reyes syndrome, Kidney toxicity
Nonsalicylate NSAID-dec supersensitivity of pain recepters and dec inflammation
ADR:upset GI, Inc clot time, Reye's syndrome, Kidney Toxicity
Term
NonSalicylate NSAIDs
Definition
Cox 1 inhib: Ibuprofen, Naproxen, Fenoprofen, ketoprofen, Indomethacin, Ketorolac, Mefenamic acid
Newer Cox-2 Inhib: Rofecoxib, Celecoxib, Valdecoxib
Term
Controlled Substance Schedule: 1-5
Definition
1:High Abuse, Can NOT rx;heroin, LSD
2:High abuse, severe dependency;Amphetamines, barbituate, narcotics
3:Mod Abuse, mod dependency;sedatives, stimulants, limited narcotics
4:Less abuse, less dependency;,ild sedatives, antianxiety, nonnarcotic analgesics
5:limited abuse and dependency, dont need Rx to get;small dose narcotics
Term
OD's can Rx
Definition
3-4 controlled substances
Term
Narcotic Drugs
Definition
acts on CNS, changes how react to pain and dec pain sensation
Codeine(3)
Oxycodone(2)
hydrocodone(3)
Propoxphene(4)
Pentazocine(4)
TRamadol
usu use in combo w/ aspirin or acetominophen
Term
Narcotic Drug ADR
Definition
CNS disturbances
GI problems
Respiratory Depression
Cardiovascular Depression
Ocular adn auditory disturbances
Term
Anti-Histamines Uses
Definition
Allergies
Acute Type I Rxns
AngioEdema
Myokemia
Term
Classification of Anti-Histamines
Definition
1. Peripherally Selective(2nd gen)-Loratadine, Cetirizine, Fexofenadine, Desloratatine
minimally sedating
2. Non-Selective(1st gen)-Mild sedating: Chlorpheniramine, brompheneramine
Mod sedating: Clemastin Strong Sedating: Diphenhydramine, promethazine
Term
CAI - Anti-Glaucoma Agents
Definition
Acetazolamide adn methazolamide
Not used long term
Typ used if pressures are very high or spiked fast
CI if patient has sulfa allergy bc these drugs are related to sulfas
CAuses kidney stones
Makes feel "crappy"
PAresthesia of ahnds and feet
Term
Hyperosmotics - Anti-Glaucoma agents
Definition
Tx. AACG
Glycerin-CI in Diabetes
Isosorbide-NO CIs
Large molecular weight liquids taken oraly (gross tasting, egg white like)
Term
Anti-Inflammatory
Definition
Used in sever, deep inflammations
Prednisone-scleritis, hyphema, keratitis, chorioretinits, vitritis
Methylprednisolone-TRaumatic optic neuropathy, demylinating optic neuropathy
Term
Immunosuppresive Agents
Definition
Used fro chronic autoimmune inflammations
cytotoxic or immune modulators
Term
Aminocaproic Acid (Amicar)
Definition
Use: Hyphema
Term
Vitamins/Minerals
Definition
Antioxidants
Use: prophylaxis
Term
Rx rights for injectibles - how many jurisdictions
Definition
32
Term
Types of injections
Definition
Subq
subconj
intralesional
peribulbar
intraocular
IM
IV
Term
Uses for Injections
Definition
1. Diagnosis-Fluorescein Angiopathy
2. Emergency- 1:1000 epi, IM, IV
3. AACG- Mannitol, IV
4. Treatment-
local anesthesia-lidocaine 1-2% subq or retrobulbar
Inflammation-steroids, preibulbar or intralesional
Infection-AB, peribulbar/AV, Iv ot intraocular
Neovascualr Membranes- Vertiprofin(IV), Pegaptanib(intravitreal), Ramizumab(Intravitreal), Bevacizumab(intravitreal)
Term
Implants-Ganciclovir(vitrasert)
Definition
Intravitreal Inj
for CMV retinitis in AIDS patients
last 5-8 months
Term
Implants-Fluocinolone(retisert)
Definition
Intravitreal injection
Use: posterior uveitis, ARMD
Term
Implant-Iodine 125
Definition
placed against sclera that has melanoma (peribulbar inj)
Term
Implant-Diabetes Mellitis
Definition
reduce retinopathy
Term
Avastin
Definition
Came about to tx colon cancer, off label use for ARMD
only $50 a shot, but still need shot every 6-8 wks
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