| Term 
 
        | vitamin/mineral drug list: |  | Definition 
 
        | - vit. A, B, C, D, E, K - tretinoin
 - calcium
 - ascorbic acid
 - nicotinamide
 - nicotinic acid
 - folic acid
 - cyanocobalamin
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - melatonin - ma-huang
 - St. John's wort
 - ginkgo
 - ginseng
 - saw palmetto
 - dehydroepiandrosterone
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | carbon monoxide, amphetamines, marijuana, LSD, caustic agents (acids & bases), morphine, meperidine, atropine, barbiturates, benzodiazepines, ethanol, methanol, neuroleptics (phenothiazines), kerosene, organophosphates, salicylates, acetaminophen, cocaine, PCP, tricyclic antidepressants, methaqualone, digoxin, phenytoin, theophylline, cyanide, heavy metals (e.g. arsenic, iron, lead, copper, mercury), oxalate |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | : ipecac, charcoal, n-acetylcysteine, BAL (dimercaprol), flumazenil, glucagons, hyperbaric oxygen, vitamin K, nitrites, digoxin-specific Fab fragments, ethanol, fomepizole, protamine, deferoxamine, pyridoxine, naloxone, methylene blue, atropine, pralidoxime, hemodialysis, hemoperfusion, alkaline diuresis |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - Vit. C (ascorbic acid) - Nicotinic acid and nicotinamide (derivatives of vitamin B3)
 - folic acid
 - cyanocobalamin (vit. B12)
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Vitamin C (ascorbic acid) is necessary in body to form what? |  | Definition 
 
        | - collagen in bones, cartilage, muscle, and blood vessels |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | Nicotinic acid and nicotinamide are ___ __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Deficiency of vitamin B3 (nicotinic acid/nicotinamide): |  | Definition 
 
        | - Pellegra: skin disease, diarrhea, dementia, depression |  | 
        |  | 
        
        | Term 
 
        | Overdose of vitamin B3 (nicotinic acid/nicotinamide): |  | Definition 
 
        | - liver toxicity - increased liver enzyme levels in blood
 - jaundice
 - ascites
 - liver failure
 |  | 
        |  | 
        
        | Term 
 
        | Folic acid (form of vitamin B)deficiency: |  | Definition 
 
        | - risk of fetus developing neural tube defects (spina bifida) - Megaloblastic and Macrocytic anemias
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - very high doses> CNS side effects |  | 
        |  | 
        
        | Term 
 
        | Cyanocobalamin is vitamin ___. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Cyanocobalamin (vit B12) deficiency helps maintain healthy __ __, __ __ __, and is also needed to make ___. |  | Definition 
 
        | - nerve cells - red blood cells
 - DNA
 |  | 
        |  | 
        
        | Term 
 
        | Deficiency of cyanocobalamin (vit B12): |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Vitamin A is required for many biological procedures like __ and __ __. |  | Definition 
 
        | vision and cellular growth |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - xeropthalmia (dry eye) - night blindness
 - total blindness
 - skin disorders
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - acne - certain leukemias
 - measles
 - malaria
 - retiniis pigmentosa
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - hypervitaminosis A - infants with acute toxicity have bulging fontanels
 - adults get brain tumor like symptoms
 - severe toxicity: eye damage, high calcium levels, liver damage
 |  | 
        |  | 
        
        | Term 
 
        | Vitamin D aids in absorption of ___, helping to from and maintain strong bones. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - rickets in children - osteomalacia in adults
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Vitamin D is used for TREATMENT OF: - hypophosphatemia
 - hypocalcemia
 - hyperparathyroidism
 - psoriasis
 - osteomalacia
 - renal osteodystrophy
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - hypercalcemia - excess bone loss
 |  | 
        |  | 
        
        | Term 
 
        | Vitamin E acts as an ___, acts through ___, and has an __ __. |  | Definition 
 
        | - antioxidant - immunomodulation
 - antiplatelet effect
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - profoundly effects CNS> ataxia and peripheral neuropathy |  | 
        |  | 
        
        | Term 
 
        | Vitamin E uses are controversial |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | increase risk of bleeding problems |  | 
        |  | 
        
        | Term 
 
        | Vitamin K is necessary for __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - defective blood clotting - increased bleeding
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Vitamin K used for treatment of: - hemorrhagic disease of newborn
 - warfarin reversal
 |  | 
        |  | 
        
        | Term 
 
        | NCCAM: branch of FDA, look at literature out there and determine if they are good studies and if the herbals are good to use or not. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Black cohosh claimed uses: |  | Definition 
 
        | - hot flashes - night sweats
 - vaginal dryness
 - other menopause symptoms
 
 STUDIES ARE MIXED AND LESS THAN 6 MONTHS LONG
 |  | 
        |  | 
        
        | Term 
 
        | Black cohosh side effects: |  | Definition 
 
        | - HA - gastric complaints
 - weight problems
 - no reports of interactions with prescriptions
 |  | 
        |  | 
        
        | Term 
 
        | Contraindication for black cohosh: |  | Definition 
 
        | - patient at risk for breast cancer should not take black cohosh |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - Monks in Middle Ages used it to decrease sexual desire - PMS
 - menopausal symptoms
 - infertility
 - acne
 
 DATA SHOWS SOME BENEFIT FOR USE IN PMS, BREAST PAIN, AND INFERTILITY IN POORLY DESIGNED STUDIES. MORE DATA NEEDED.
 |  | 
        |  | 
        
        | Term 
 
        | OBGYNS use ___ to treat infertility and PMS symptoms. But be careful b/c it interacts with __ __ and other hormones. |  | Definition 
 
        | - chasteberry - birth control pills
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - common colds - flu
 - URIs
 
 NO STUDY HAS SHOWN ANY EVIDENCE OF IT WORKING THOUGH MORE RESEARCH IS UNDERWAY REGARDING EFFECTIVENESS IN URI.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - asthma - anaphylaxis
 - rashes
 |  | 
        |  | 
        
        | Term 
 
        | ___ is related to plants in the daisy family including ragweed. So people with allergies should be careful. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Ephedra aka __ __ or ___ ___. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - weight loss - colds
 - fever
 - flu
 - headaches
 - asthma
 - wheezing
 - nasal congestion
 |  | 
        |  | 
        
        | Term 
 
        | Ephedra increases risk of __, __, and ___ problems, as well as  __ __ __ and __. |  | Definition 
 
        | - heart, psychiatric, and gastrointestinal problems - high blood pressure and stroke
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | nausea, anxiety, headache, psychosis, kidney stones, tremors, dry mouth, irregular heart rhythms, heart damage, high blood pressure, restlessness, sleep problems, irritation of the stomach, and increased urination 
 NO LONGER FDA APPROVED AS OF 2004
 |  | 
        |  | 
        
        | Term 
 
        | With fiber/flax seed the benefits outweigh the risks. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Flax seed. Take 1 tablespoon per day. This is the largest source __, largest source of ___ __, and largest source of __ __. |  | Definition 
 
        | - fiber - omega 3s
 - plant estrogen
 |  | 
        |  | 
        
        | Term 
 
        | Data on flax and fiber show that it is an effective __. There is mixed data on it lowering ___ and preventing __ __. No side effects. |  | Definition 
 
        | - effective laxative - lowering cholesterol and preventing heart disease
 |  | 
        |  | 
        
        | Term 
 
        | 1 tablespoon flax seed= 9 grams fiber |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Flax has omega 3 in form of ___ while fish oil has omega 3 in form of ___. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - tmt of high cholesterol - tmt of hypertension
 - heart disease
 - stomach cancer
 
 DATA SHOWS THAT IT DOES NOT WORK
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | breath and body odor, heartburn, upset stomach, and allergic reactions, acts like a blood thinner similar to ASA, interferes with some anti-HIV meds |  | 
        |  | 
        
        | Term 
 
        | Garlic acts like a ___ __ like ASA, so it needs to be stopped before surgery. It also interferes with __ meds. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - stomach aches - nausea
 - diarrhea
 
 safely relieve pregnancy-related nausea and vomiting; studies are mixed on effect on chemo-induced nausea
 |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - improve memory - prevent Alzheimer's disease and other dementia
 - may also reduce symptoms of claudication
 
 studies are promising but more needed
 |  | 
        |  | 
        
        | Term 
 
        | Ginko Biloba side effects: |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - boost immune system - improves mental and physical performance
 - tmt of erectile dysfunction
 - menopause symptoms
 - lower blood glucose
 
 Data shows it may be effective at lowering blood glucose, but no data for other claims.
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - headaches - sleep problems
 - GI problems
 - caution in patients with Diabetes
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - osteoarthritis tmt 
 good evidence to support the use of glucosamine sulfate in the treatment of mild-to-moderate knee osteoarthritis
 |  | 
        |  | 
        
        | Term 
 
        | Glucosamine side effects: |  | Definition 
 
        | - upset stomach - drowsiness
 - insomnia
 - headache
 - skin reactions
 - sun sensitivity
 - nail toughening
 - may increase bleeding risk
 |  | 
        |  | 
        
        | Term 
 
        | Kava (aka kava pepper) uses: |  | Definition 
 
        | - anxiety - insomnia
 - menopausal symptoms
 
 Some evidence shows may be effecive against anxiety, but FDA warns it can cause liver toxicity
 |  | 
        |  | 
        
        | Term 
 
        | What herb is supposed to help with anxiety but may cause liver toxicity? |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - liver damage/hepatitis/liver failure - dystonia
 - may interact with Parkinson's drugs
 |  | 
        |  | 
        
        | Term 
 
        | what herb used to treat anxiety may interact with Parkinson's drugs: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Noni is aka ___, __ __, __ __, and __ __. |  | Definition 
 
        | - Morinda - Indian mulberry
 - Hog apple
 - Canary wood
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - joint pain - skin conditions
 - cardiovascular disease
 - diabetes
 
 Data has shown antioxidant, immune-stimulating, and tumor-fighting properties, but not well studied;
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - high potassium (so not good for patients with liver disease) - liver disease
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | kidney disease b/c causes high potassium |  | 
        |  | 
        
        | Term 
 
        | ALA omega 3s are in __, __,__, and __ __. |  | Definition 
 
        | flax soy
 walnuts
 vegetable oils
 |  | 
        |  | 
        
        | Term 
 
        | EPA and DHA omega 3s are in __ and __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | In pregnancy you need ____ by third trimester to help brain development. |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | - lower TGs - reduce risk of death
 - reduce risk of heart attack
 - used to treat abnormal heart rhythms
 - reduce risk of stroke
 - lowers blood pressure slightly
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - fishy taste - increased bleeding at high doses
 - potentially harmful contaminants such as dioxins, methylmercury, and polychlorinated biphenyls (PCBs) are found in some species of fish
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - PMS - menopausal symptoms
 - eczema
 
 data not very supportive
 |  | 
        |  | 
        
        | Term 
 
        | side effects of primrose oil: |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Red rice yeast is aka ___. One of these __ __ is a potent inhibitor of ___ ___ __ and is aka __ or ___. |  | Definition 
 
        | - Monacolins - Monacolin K
 - HMG-CoA reductase
 - Mevinolin
 - Lovastatin
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - cholesterol lowering agent 
 supportive evidence for TG lowering and LDL lowering properties; no strong evidence exists for cardiovascular benefits or diabetes
 |  | 
        |  | 
        
        | Term 
 
        | Side effects of Red Rice Yeast: |  | Definition 
 
        | similar to those for the prescription drug lovastatin (MevacorĀ®) heartburn, gas, bloating, muscle pain or damage, dizziness, asthma, and kidney problems are possible; people with liver disease should not use red yeast products; may increase the risk of bleeding. Warning
 |  | 
        |  | 
        
        | Term 
 
        | Red rice yeast is a precursor to the __ drugs. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Saw Palmetto aka __ __ __ __ aka __ __. |  | Definition 
 
        | - American dwarf palm tree - Cabbage palm
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - urinary symptoms associated with enlarged prostate - chronic pelvic pain
 - bladder disorders
 - decreased sex drive
 - hair loss
 - hormone imbalances
 
 not enough scientific evidence to support the use of saw palmetto for reducing the size of an enlarged prostate or for any other conditions
 |  | 
        |  | 
        
        | Term 
 
        | Saw palmetto side effects: |  | Definition 
 
        | - stomach discomfort - tender breasts
 - decreased libido
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | - depression - anxiety
 - sleep disorders
 
 some effect shown compared to placebo in mild depressive disorder but more well-developed studies are needed and there are safety concerns
 |  | 
        |  | 
        
        | Term 
 
        | St Johns Wort interacts with __ __ __. |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | St. John's wort side effects: |  | Definition 
 
        | - increased sensitivity to sunlight - anxiety
 - dry mouth
 - dizziness
 - GI symptoms
 - fatigue
 - headache
 - sexual dysfunction
 - tons of drug interactions including birth control
 |  | 
        |  |