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Pharmacology-Equations
Self paced pharm. UMKC-M3
10
Real Estate & Planning
2nd Grade
08/09/2012

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Term
This equation allows you to calculate an oral or intravenous loading dose needed to achieve a desired target [ ]. This also allows you to calc. how much additional drug should be administered to raise an existing drug concentration to a more desirable target [ ]. 
Definition
Loading Dose
Term

DeltaC x Vd


F x S

 

Definition
Loading Dose
Term
Equation for Loading Dose
Definition

ΔC x Vd


F x S

 

Term
What is Vd
Definition
Volume of distribution. This is a unique constant for each drug
Term
What does S represent in LD
Definition
Fraction of active drug present w/in the salt. 
Term
How do you calculate S if the drug is not administered as a salt?
Definition
It is always 1
Term
What equation allows you to determine what [ ] will be achieved following administration of an oral or IV loading dose. 
Definition
Peak Concentration following a single dose. 
Term
What is the equation for peak concentration following a single dose
Definition

F x S x Loading Dose


Vd

 

Term

 

What is the equation 

ΔCp = F x S x LD


Vd 

used for?

 

 

Definition

To calculate the peak concentration following a single dose. 

*notice that this equation is simply a rearrangement of the LD equation. 

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