| Term 
 | Definition 
 
        | the first antibiotic drugs developed that effectively treated infections |  | 
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        | Term 
 | Definition 
 
        | they slow or retard the multiplication of bacteria |  | 
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        | Term 
 | Definition 
 
        | they destroy the bacteria |  | 
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        | Term 
 | Definition 
 
        | they destroy a large number of different types of bacteria from the same strain, such as gram negative bacteria |  | 
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        | Term 
 
        | narrow spectrum antibiotics |  | Definition 
 
        | drugs that are specific to particular bacteria |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | ability of bacteria to produce substances that inactivate or destroy the antibiotic |  | 
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        | Term 
 | Definition 
 
        | they are active against bacteria |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | are primarily bacteriostatic because of their ability to inhibit the activity of folic acid in bacterial cell metabolism |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | UTIs and acute otitis media Ulcerative colitis
 |  | 
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        | Term 
 
        | Sulfa uses Mafenyde (Sulfamylon) and silver sulfadiazine (Silvadene)
 |  | Definition 
 
        | are topical sulfonamides used in the treatment and prevention of infections in second and third degree burns. |  | 
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        | Term 
 | Definition 
 
        | Anorexia, NVD, abdominal pain, and Stomatitis (inflammation of the mouth) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Chills, fever, Crystalluria (crystals in the urine), photosensitivity |  | 
        |  | 
        
        | Term 
 
        | hypersensitivity to sulfa |  | Definition 
 
        | urticaria (hives), pruritus (itching), Toxic Epidermal Necrolysis (TEN), or Steven Johnson's Syndrome (SJS) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | lesions on the skin and mucous membranes, eyes. Lesion may apprea as red wheals or blisters, often starting on the face, mouth, lips, neck and extremities. |  | 
        |  | 
        
        | Term 
 
        | sulfa most common adverse reaction with topical application |  | Definition 
 
        | is burining sensation or pain when the drug is applied to the skin |  | 
        |  | 
        
        | Term 
 
        | hematologic changes during prolonged sulfa therapy |  | Definition 
 
        | leukopenia-decrease in # of WBC thrombocytopenia-decrease in # of
 platelets
 aplastic anemia- anemia due to deficient RBC production in the bone marrow
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | renal impairment, hepatic impairment, or bronchial asthma |  | 
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        | Term 
 
        | Contraindications to Sulfa's |  | Definition 
 
        | hypersensitivity, during lactation, and children under 2 years of age, not used at the end(at term) pregnancy |  | 
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        | Term 
 
        | Sulfa's are used with caution in pts with |  | Definition 
 
        | renal impairment, hepatic impairment, or bronchial asthma, pregnancy Cat C |  | 
        |  | 
        
        | Term 
 
        | Interactions for Sulfa': Oral anticoagulants
 Methotrexate
 hydantoins
 |  | Definition 
 
        | increased action of anticoagulants increased bone marrow suppression
 increased serum hydantoin level
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | when diabetic pts are prescribed sulfa's assess for a possible |  | 
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        | Term 
 
        | Cranberries/cranberry juice |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | what self-remedies have you tried before seeking a health care provider |  | Definition 
 
        | During the pre-admin assessment ensure you ask? |  | 
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        | Term 
 
        | urine culture, urinalysis, complete blood count, intravenous pyelogram, renal function tests, and examination of the stool |  | Definition 
 | 
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        | Term 
 
        | evaluates response to the drug; relief of symptoms and a decrease in temp.(if temp increases report to HCP immediately) |  | Definition 
 
        | ongoing assessment the nurse? |  | 
        |  | 
        
        | Term 
 
        | stool samples, contact HCP if changes in number and appearance. |  | Definition 
 
        | If taking sulfasalazine for ulcerative colitis, ensure the pt inspects all? |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | If administering a sulfa for a burn, the nurse inspects the areas every? |  | 
        |  | 
        
        | Term 
 
        | 1.Impaired urinary elimination-related to effect on the bladder from sulfa's 2.Impaired skin integrity- related to burns
 3.Impaired skin integrity-related to photosensitivity or sever allergic reaction to sulfa
 4.risk for(secondary)infection-lowered WBC count resulting from sulfa therapy
 |  | Definition 
 | 
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        | Term 
 | Definition 
 
        | People may be receiving this to ____ infection?
 |  | 
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        | Term 
 | Definition 
 
        | They are given at what time? |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | May cause urine and skin to take on an orange-yellow color; normal |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Instruct pt to drink a full glass of water when taking an oral sulfa, and at least __ glasses a day until therapy is finished |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Drink at least ____ml or more per day to prevent crystalluria and stones. Also important to measure intake/output |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | renal impairmant is common in older adults, there is an increased danger of the sulfa causing additional renal damage, and may be hesistant about the increase of fluids because of the fear of... |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | If applying the topical sulfa for a burn, use a sterile glove and apply __ inch thick |  | 
        |  | 
        
        | Term 
 
        | protective clothing and sunscreen when outside; and should be inspected 14 days after therapy in which reactions can still occur |  | Definition 
 
        | Due to photosensitivity the pt should be cautioned to wear |  | 
        |  | 
        
        | Term 
 
        | leukopenia(may result in signs of an infection) and thrombocytopenia. |  | Definition 
 
        | Nurse monitors for ___ and ___ (risk for secondary infection) |  | 
        |  | 
        
        | Term 
 
        | fever, sore throat, and cough |  | Definition 
 
        | Leukopenia may result in S/S of an infection such as |  | 
        |  | 
        
        | Term 
 
        | easy bruising and unusual bleeding after moderate to slight trauma to skin or mucous membranes **use soft-bristled toothbrush**
 |  | Definition 
 
        | Thrombocytopenia is manifested by |  | 
        |  | 
        
        | Term 
 
        | fever,skin rash, other skin problems, N, V, unusual bleeding or bruising, sore throat or extreme fatigue |  | Definition 
 
        | Notify the primary HCP immediately if the following should occur |  | 
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