Term
Blocks Viral penetration/uncoating (M2 protein). Prophylaxis and treatment for influenza A
Also causes a release of dopamine from intact nerve terminals (for Parkinsons) |
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Definition
Amantadine
Toxicity: ataxia, dizziness, slurred speech |
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Term
| Inhibits influenza neuraminidase, decreasing the release of progeny virus |
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Definition
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Term
Inhibits synthesis of guanine nucleotides by competitively inhibiting IMP dehydrogenase
Used for RSV and chronic hepatitis C |
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Definition
Ribavirin
Toxicity:
Hemolytic anemia
Teratogenic |
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Term
Monophosphorylated by viral thymidine kinase. Inhibits viral DNA polymerase by chain termination
Used for HSV, VZV, EBV |
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Definition
Acyclovir
Mech of resistance: lack of thymidine kinase |
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Term
Similar to acyclovir, except guanine analog formed by CMV viral kinase
Used to stop DNA polymerase |
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Definition
Ganciclovir
Toxicity: leukopenia, neutropenia, thrombocytopenia, renal toxicity |
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Term
Viral DNA polyermase inhibitor that does not require viral kinase activation
Used when ganciclovir fails |
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Definition
Foscarnet
Does not cause bone marrow suppression |
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Term
Glycoproteins from human leukocytes that block various stages of viral RNA and DNA synthesis
Used for Chronic hepatitis B and C, kaposi sarcoma |
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Definition
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Term
Glycoproteins from human leukocytes that block various stages of viral RNA and DNA synthesis
Used for Multiple sclerosis |
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Definition
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Term
Glycoproteins from human leukocytes that block various stages of viral RNA and DNA synthesis
Used for NADPH oxidase deficiency |
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Definition
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