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Pharmacology 8
Drug Terminology
31
Pharmacology
12th Grade
02/07/2011

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Term
acetylcholine
Definition
the prinicipal neurotransmitter of the parasympathetic nervoes system acetylcholine activates cholinergic receptor sites throughout the body. Its action is blocked by anticholinergic drugs.
Term
addiction
Definition
an acquired physical or psychological dependence on a drug characterized by the habitual use of the drug, the tendency to increase the drug dose to experience the same or greater effects, increasing tolerance to the effects, and the appearance of withdrawal symptoms when deprived of the drug. Drugs with addictive potential are legally referred to as controlld substances or schedule drugs.
Term
adrenergic
Definition
a receptor for the sympathetic nervous system that is activated by the neurotransmitter norepinephrine. There are three common types of adrenergic receptors often mentioned in pharmacology: alpha, beta1, beta2
Term
ampule
Definition
a small, slender, all-glass container with a narrow neck, an ampule contains certain liquid drugs for injection or intravous use only. The ampulse is broken open by placing an alcohol swab around the neck and briskly snapping both ends of the ampulse. An ampulse contains enough drug for one dose. Once an ampulse is opened, the drug inside it is not saved or reused because it does not contain any preservative. Ampulses often contain drugs used in emergency resuscitation such as an epinephrine or calcium chloride. Ther term ampule has no proper abbreviation and should always be written in full.
Term
analgesic
Definition
a drug that selectively supresses pain without producing sedation.
Term
anticholinergic
Definition
a drug that opposes the action of acetylcholine at the site of cholinergic receptors. Exert a predictable set of side effects. These are
A-anticholinergic
B-blurred vision, bladder retention
C-constipation
D-dry mouth
Term
anti-inflammatory
Definition
a drug used to decrease symptoms of inflammation by inhibiting the release of prostaglandins
Term
antineoplastic
Definition
a drug that is selctively toxic by rapidly dividing cells such as malignant cells and is used to treat cancer (neoplasm means tumor)
Term
antipruritic
Definition
a drug that prevents ofr relieves itching
Term
antiseptic
Definition
a drug that inhibits the growth of bacteria, but does not destroy them. Usually used topically, not internally.
Term
antitussive
Definition
a drug that suppresses coughing
Term
bioavailability
Definition
That portion of the toatl drug dose, after absorption, that is actually, available to interact with receptors and produce a therapeutic effect. Bioavailability is determined by a number of factors influencing absorption, including drug composition, particle size, and stomach pH
Term
diluent
Definition
an agent such as sterile normal saline of sterile water that is used to reconstitute the powdered form a drug to prepare it for injection.
Term
diuretic
Definition
an drug used to treat edema and hypertension by causing the kidneys to excrete more sodium and water
Term
drug tolerance
Definition
a decreased susceptibility to the effects of a drug because of continued use.
Term
half-life
Definition
the time required for drug levels in the serum to decrease from 100% to 50%. The half life of a drug can be significantly prolonged when liver or kidney disease increases metabolism and excretion of a drug. The shorter a drug's half-life, the more frequently it must be administered to sustain therapeutic levels. Drugs with a short halflife may be manufactured in a slow-release form to provide sustained drug levels with less frequent doses
Term
hypodermic
Definition
a nonspecific term for any injection administered under the skin, or for the syringe used to give the injection.
Term
LA
Definition
abbreviation for long acting. A part of the trad namem of sustained-release, long acting drugs.
Term
loading dose
Definition
if the therapeutic effect of a drug is desired immediately to treat a medical disease, a large dose of the drug may be administered at once. This is known as a loading dose. This is generally twice the maintenance dose.
Term
maintenance dose
Definition
the standard dose prescribed by the physician for any drug.Generally half the loading dose
Term
mydriatic
Definition
dilates the pupil of the eye
Term
needles
Definition
classified according to gauge and length
gauge-the inside diameter of the needle. The lower the gauge number, the larger the inside diameter. also known as the bore.
Term
peak level
Definition
highest serum level achieved following a single dose of a drug.
Term
placebo
Definition
sugar pills or injections of sterile normal saline solutions. Used in drug trials
Term
prophylaxis
Definition
this type of drug is administered before the onset of a disease or other condition to prevent its occurence.
Term
SA
Definition
sustained action. Sustained release, long acting drugs.
Term
trough level
Definition
The lowest serum level of a drug that occurs just before the next does is to be given
Term
vasodilator
Definition
a drug that relaxes the smooth muscle of blood vessals to improve blood flow
Term
vasopressor
Definition
a drug that consricts the smooth muscle of blood vessals to increase the blood pressure
Term
vial
Definition
small glass bottle containing a liquid or powder for injection. It has a rubber stopper in the cap that allows diluent to be injected to reconstitute a powdered drug.
Term
XR
Definition
extended release
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