Term
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Definition
Systole- contraction
Diastole- relaxation |
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Term
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Definition
SA Node
AV Node
Bundle of His
Purkinje System |
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Term
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Definition
| Positive charge outside of cell |
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Term
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Definition
| Na & Ca flow in, K flows out |
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Term
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Definition
Beta 1- positive chronotropic and inotropic effects
Alpha 1- vessel constriction
Beta 2- vessel dilation |
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Term
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Definition
Increasing HR
Increasing SV
Increasing efficiency of muscle
Physiologic enlargement |
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Term
| Disorders that respond to pharmacologic therapy |
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Definition
valvular disease
cardiac arrhythmias
myocardial disease |
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Term
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Definition
Control rhythm
Maintain or increase output
relieve fluid accumulation
increase oxygenation |
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Term
| positive inotropic drug qualities |
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Definition
Pros- improve strength of contraction
cons- increase 02 demand of heart
May damage contractile tissue
may increase occurrence of arrythmias |
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Term
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Definition
positive inotropic
digitalis derivative
pros-improved cardio contractility, decrease HR, antiarrhythmia effects, decrease dyspnea
Primary Action- increase force of contraction, decrease rate of contraction, improve baroreceptor function
Clinical use-CHF, atrial fib, Sv tachycardia
forms-digoxin (injectable, tabs, caps, elixir) |
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Term
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Definition
Positive inotropic
Sympathomimetic
actions: increase force/rate of contraction, constrict peripheral blood vessel, elevate blood glucose
con: short serum half lives |
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Term
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Definition
catecholamine/positive inotropic
uses: cardiac resuscitation, tx anaphylaxis
forms: 1:10000 or 1:1000
cons: hypertension, arrhythmias, anxiety, excitability |
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Term
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Definition
catecholamine/positive inotropic
use: tx of acute heart failure, oliguric renal failure, tx of shock
cons: vomiting, tachycardia, dyspnea, variations in bp |
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Term
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Definition
Positive inotropic
IV
Short term |
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Term
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Definition
Positive inotropic
Oral
Long term |
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Term
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Definition
positive inotropic
av insufficiency or dilated myocardiopathy
cons: anorexia, lethargy, diarrhea
CTX: hypertrophic cardiomyopathy, aortic stenosis |
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Term
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Definition
class IA NA channel blocker
antiarrhytmic
use: vent arrhythmias, tachy, a fib
cons: anorexia, v/d, hypotension |
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Term
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Definition
Class IA NA channel blocker
premature vent contractions, vent tachy, some forms of attach
cons: anorexia, v/d, hypotension |
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Term
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Definition
class IB Na channel blocker
use: control of pvc's, vtach |
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Term
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Definition
class II beta adrenergic blocker
antiarrhythmic
tx: hypertrophic cardiomyopathy, arrhythmias, hypertension
cons: bradycardia, hypotension, worsen heart failure, bronchospasm, lethargy, depression |
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Term
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Definition
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Term
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Definition
Class IV Ca channel blocker
antiarrhythmic
use: supraventricular tach, atrial flutter, fib
cons: hypotension, bradycardia, tachycardia, pulmonary edema, worsening CHF |
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Term
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Definition
vasodilator
arterial
use: reduce afterload w/CHF, esp caused by mitral insufficiency
cons: hypotension, v/d, Na& water retention &tach |
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Term
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Definition
venodilator
reduce preload & pulmo edema |
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Term
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Definition
aa&vv dilator
use: tx of CHF, dilated cardio in dogs, systemic & pulmonary hypertens
cons: hypotension, syncope, v/d |
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Term
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Definition
Combined vasodilators
tx of class II, III, IV heart failure
captopril, enalapril
cons: azotemia, BUN & creatinine rise |
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Term
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Definition
diuretic
most efficient for removing edema w/heart failure
cons: hypokalemia, dehydration, hyponatremia, ototoxicity (cats), weakness, shock |
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Term
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Definition
diuretic
POTASSIUM SPARING
normally used w/other diuretic |
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