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Pharmacogenomic Cards
Given the generic name of an FDA-approved drug discussed in class (Maraviroc, Imatinib, Warfarin, Fluoxetine, Fluorouracil, Trastuzumab, Carbamazepine, Mercaptopurine, Irinotecan, Abacavir, Primaquine
12
Pharmacology
Graduate
11/17/2012
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Term
Maraviroc
 Definition

CCR5
 
Term
Imatinib
 Definition
BCR-ABL
Right patient with right disease
Term
Warfarin
 Definition
 CYP2C9, VKOR
 Right initial dose
Term
Fluoxetine
 Definition
CYP2D6
 Right patient
Term
Fluorouracil
 Definition
 DPD
Right patient and right dose
Term
Trastuzumab
 Definition
HER2
 
Term
Carbamazepine
 Definition
 HLA-B*1502 (HLA: human leukocyte antigen, serotype: B, gene allele: B*1502)
 
Term
Mercaptopurine
 Definition
TPMT
 
Term
Irinotecan
 Definition
 UGT1A1
 
Term
Abacavir
 Definition
HLA-B*5701 (HLA: human leukocyte antigen, serotype: B, gene allele: B*5701)
 
Term
Primaquine
 Definition
 G6PDH
 
Term
Cetuximab
 Definition
 EGFR and K-RAS
 
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