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Pharmaceutics Excipients
N/A
12
Other
Graduate
10/15/2010

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Cards

Term
Solvents
Definition
dissolve drug; purified water, sterile water, alcohol, peanut oil, mineral oil
Term
Vehicles
Definition
dissolve or disperse drug (carrying agent); syrups (sugar solutions), elixirs (hydroalcoholic)
Term
Flavors and sweeteners
Definition
make drug palatable; flavors: peppermint, vanillin, cocoa, cinnamon oil; sweeteners: sucrose, mannitol, sorbitol, glycerin, dextrose
Term
Preservatives
Definition
prevent microbial growth; antifungal: parabens (mehtyl, ethyl, butyl), benzoic acid, sodium benzoate; antimicrobial: benzalkonium chloride, chlorbutanol, phenol
Term
Stabilizers (antioxidants, chelating agents)
Definition
prevent decomposition; antioxidants: ascorbic acid, sodium ascorbate, sodium metabisulfite; chelating agents: edetic acid, edetate disodium
Term
Diluents/fillers
Definition
increase bulk of formulation; microcrystalline cellulose, starch, lactose, mannitol
Term
Binders
Definition
cause adhesion; sodium carboxymethyl cellulose, ethyl cellulose, gelatin
Term
Disintegrating agents
Definition
help break tablet after incubation in water; microcrystalline cellulose, starch
Term
Antiadherents/lubricants/ glidants
Definition
reduce friction during compression, improve flow; stearates (calcium, magnesium, zinc) talc
Term
Surfactants
Definition
help dispersion; sodium lauryl sulfate (SLS)
Term
Ointment bases
Definition
petrolatum, polyethylene glycol (PEG)
Term
Coating agents
Definition
taste masking, enteric coating (protection), sugar coating (liquid glucose, sucrose), film coating (ethyl cellulose, methyl cellulose), enteric coating (cellulose acetate phthalate, shellac)
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