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pharm
general anesthetics
19
Medical
Graduate
02/17/2009

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Cards

Term
MOA of general anesthetics (inhaled, BZs, barbiturates, etomidate, propofol)
Definition
act at GABA-mediated Cl channel
Term
inhaled anesthetic with low blood-gas partition coefficient
Definition
nitrous oxide
Term
inversely related to potency of anesthetic
Definition
MAC (minimum alveolar concentration)
Term
inhaled anesthetics metabolized by liver enzymes
Definition
halothane, methoxyflurane
Term
SE of most inhaled anesthetics
Definition
decreased arterial blood pressure
Term
inhaled anesthetics that are myocardial depressants
Definition
halothane, enflurane (depress the HEart)
Term
inhaled anesthetic that causes peripheral vasodilation
Definition
isoflurane
Term
inhaled anesthetic that sensitized myocardium to arrythmogenic effects of catecholamines
Definition
halothane
Term
inhaled anesthetic that can produce hepatitis
Definition
halothane
Term
inhaled anesthetic least likely to lower BP, has smallest effects on respiration
Definition
nitrous oxide
Term
metabolism releases fluoride, may cause renal insufficiency
Definition
methoxyflurane
Term
prolonged exposure to this anesthetic can cause megaloblastic anemia
Definition
nitrous oxide
Term
pungent anesthetic with high incidence of coughing and vasospasm
Definition
desflurane
Term
DOC for malignant hyperthermia caused by use of halogenated anesthetics
Definition
dantrolene
Term
IV barbiturate, used as pre-operative anesthetic
Definition
thiopental
Term
produces 'dissociative anesthesia", cardio stimulant that increases ICP, hallucinations during recovery
Definition
ketamine
Term
opioid ass'd with respiratory depression, but useful in high risk patients who may not survive full general anesthesia
Definition
fentanyl
Term
fentanyl + droperidol + nitrous oxide creates this state of analgesia/amnesia
Definition
neuroleptanesthesia
Term
rapid anesthesia/recovery, antiemetic, used for outpatient surgery, can cause marked hypotension
Definition
propofol
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