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| Three types of Medications used to treat anxiety and sleep disorders |
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Definition
Antidepressants Benzodiazepines Barbiturates |
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| Withdrawal S/S of Sedatives, Hypnotics, Sedative Hypnotics |
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| Life threatening, fever, psychosis, seizures, tachycardia, hypotension, muscle cramps, memory impairment, loss of appetite, auditory and visual disturbances, insomnia, agitation, anxiety |
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| Major Types of Anxiety Disorders |
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Definition
Situational anxiety Generalized anxiety disorder (GAD) Panic disorder Phobias Obsessive-compulsive disorder Post-traumatic stress disorder |
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| Nonpharmacologic Therapies to Cope with Anxiety |
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Cognitive behavioral therapy Counseling Biofeedback techniques Meditation |
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| bind to GABA receptors increasing there effects (slowing neurotransmission) |
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| Uses:anxiety, insomnia, szs, & alcohol withdrawal |
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| Librium, Valium, Ativan, Versed |
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blocks the receptors from binding with the benzo BENZO ANTIDOTE |
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| Romazicon works how fast? |
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| IV over 30 seconds repeated every minute as needed |
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Highly addictive Withdrawal s/s are severe and can be fatal Overdose s/s-resp depression, hypotension, pin point pupils, & shock Avoid other sedatives IM can cause necrosis |
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| Nonbenzodiazepines, Nonbarbiturate (CNS depressant) EX |
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Definition
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| Nonbenzodiazepines, Nonbarbiturate (CNS depressant) AX |
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| Nonbenzodiazepines, Nonbarbiturate (CNS depressant) Use |
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| Nonbenzodiazepines, Nonbarbiturate (CNS depressant) SE |
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Definition
| mild nausea, dizziness, diarrhea, daytime drowsiness, amnesia, sleepwalking, ingesting carbohydrates while sleepwalking |
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| Nonbenzodiazepines, Nonbarbiturate (CNS depressant) IMPS |
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Definition
works better if not used everyday Watch for over sedation |
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| binds to serotonin and dopamine receptors and increases norepi metabolism |
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Decreases anxiety w/o causing sedation Less likely to cause dependency May take several weeks to be therapeutic |
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Natural hormone released from the pineal gland at night Tryptophan is converted to serotonin and then to melatonin Causes alertness and temperature to decrease, inviting sleep Levels vary with age |
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Agitation, excessive talking, elevated mood, grandiose thoughts Flight of ideas, constant movement, impulsive behavior Inflated self-esteem, racing thoughts, short attention span |
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| Tricyclic Antidepressants Ax |
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Definition
| blockmonoamine reuptake, intensifying the effects of norepi and serotonin |
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| Tricyclic Antidepressants EX |
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| Tricyclic Antidepressants SE |
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Definition
| orthostatic hypotension, anticholineric effects, sedation, cardiotoxic, szs, hypomania, sexual dysfunction, HTN crisis |
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| Tricyclic Antidpressants Nursing IMps |
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Definition
Usually given once a day at bedtime Watch for suicide DO NOT give with MAOIs-severe HTN from excessive adrenergic stimulation May take several weeks to be therapeutic Many drug interactions |
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| decrease reuptake of serotionin into presynaptic nerve terminals |
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| depression, OCD, panic dxs, bulimia nervosa |
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May take several weeks to be therapeutic Less SEs Don’t give with MAOIs-serotonin syndrome Do not discontinue abruptly |
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| inhibit monoamine oxidase (terminates the actionof dopamine, norepi, epi, and serotonin) |
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| orthostatic hypotension, HA, insomnia, and diarrhea |
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Lots of contraindications and interactions Watch for liver, renal, and blood dysfunctions May lower sz threshold |
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| szs, fatigue, neuromuscular impairment, wt gain |
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| MOOD STABILIZER THERAPEUTIC INDEX |
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Very narrow therapeutic index 0.6-1.4 Toxicity begins at 1.5 Death may occur at 2.5 |
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Lots of interactions Significant changes in Na intake can increase risk for toxicity Monitor renal function |
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| insomnia, nervousness, anorexia, wt loss |
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Can cause dependency Monitor weight closely Report any ticks that develop Monitor EKG |
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| ADHD NON CNS STIMULANTS EX. |
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Definition
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| ADHD-Non-CNS Stimulants IMPS |
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Definition
Often used in conjunction with another med Not very effective if used alone |
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| Most common psychotic disorder |
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Definition
Most common psychotic disorder Manifests in men aged 15 to 24 years Manifests in women in aged 25 to 34 years |
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Hallucinations, delusions, or paranoia Strange and irrational behavior Severe depression
Alternating rapidly between extreme hyperactivity and stupor Attitude of indifference or detachment toward life activities Deterioration of personal hygiene and/or job or academic performance Withdrawal from social and interpersonal relationships |
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| add on to normal behavior |
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| subtract from normal behavior |
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| schizo ass. with what receptro in the brain |
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| Antipsychotic Med's General Info |
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Definition
Do not cure schizophrenia Are effective as long as the client takes the medication Have multiple undesirable side effects Selection of appropriate medication related to several factors |
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| Conditions that may mimic the behaviors of schizophrenia |
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Definition
Drug use Brain neoplasm Infections Hemorrhage |
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| Schizoaffective disorder characterizations |
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Definition
Distorted perceptions Hallucinations Delusions Extreme depression following these symptoms |
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| Extrapyramidal Symptoms (EPS) |
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Definition
Tardive dyskinesia Acute dystonias Akathisia Stooped posture, shuffling gait Parkinsonism symptoms |
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| Neuroleptic Malignant Syndrome (NMS) |
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Definition
| Toxic reaction to therapeutic doses of antipsychotic drug |
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| Neuroleptic Malignant Syndrome (NMS) s/s |
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Elevated temperature Unstable blood pressure Profuse sweating Dyspnea Muscle rigidity Incontinence |
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| Typical Antipsychotic aka 1st gen |
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| prevent dopamine and serotonin from binding to receptors |
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| Typical Antipsychotic IMPS |
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Many SEs-EPS, etc May give with Cogentin |
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| Cause less sedation and fewer SEs, but still can cause EPS |
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| Atypical PYSCHOTICS AKA 2nd Gen ax |
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Definition
| may block several receptors in the brain |
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| Dopamine System Stabilizers EX |
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| Dopamine System Stabilizers IMPS |
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