Term
| Name 5 Normal Flora of the Pharynx/Upper GI |
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Definition
| Staph epidermis, Staph aureus, strep pneumoniae, H flu, H paraflu, neisseria, bactroides, candida |
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Term
| Name normal flora of the skin |
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Definition
| Staph epidermis, Staph aureus, streptococci, clostridium, candida, propionibacterium |
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Definition
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Term
| Most common cause of epiglottitis in children |
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Definition
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Term
| Major cause of bronchiolitis in children less than 1 year old |
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Definition
| Respiratory Syncytial Virus |
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Definition
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| Causes most respiratory infections in children (Croup in infants) |
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Definition
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Definition
| Progressive decrease in effectiveness of a drug after time - requires increasing drug amount to produce the same effect due to increased metabolism of the drug by the body |
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Definition
| The intended effect of a drug |
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Definition
| A sudden diminished response to a drug after routine usage - due to tolerance. |
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Definition
| an allergic reaction between an allergic antigen (drug) and immunoglobulins |
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Definition
| Drugs that are known to cause birth defects |
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Definition
| The ability of a drug to produce a desired therapeutic effect |
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Term
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Definition
| The tendency of a drug to combine with a matching receptor |
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Term
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Definition
| The synergistic action of 1 inactive substance working with an active substance produces a total effect greater than that of the active substance alone |
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Definition
| The recommended amount of a drug that should be used to obtain the desired clinical effect. |
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Term
| Median Lethal Dose (LD50) |
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Definition
| The dose at which 50% of the test animals die |
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Term
| Median Effective Does (ED50) |
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Definition
| The dose at which 50% of the test animals show the desired effect. |
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Term
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Definition
| Ratio of LD50 to ED50 that gives a relative indication of the safey of the drug. The closer the TI is to zero, the more toxic the drug. |
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Definition
| Administering sufficient quantities of a drug to attain therapeutic levels quickly |
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Definition
| The amount of drug required to keep a desired mean steady state concentration in the tissues |
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Definition
| The time necessary to reduce the initial dose by half. |
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Definition
| Occurs when two drugs together produce an effect greater than the 2 drugs alone could produce. |
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Definition
| The increased activity of a drug when repeated doses accumulate in the body and exert a greater biologic effect than the initial dose. |
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Definition
| The proportion of drug that reaches systemic circulation to produce effect required - affected by absorption, inactivation, blood flow, volume |
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