Term
| structurally related to ACh, produces muscle paralysis to facilitate surgery or artificial ventilation, full doses lead to respiratory paralysis |
|
Definition
|
|
Term
| drugs that potentiate and prolong effects of neuromuscular blockade |
|
Definition
| inhaled anesthetics (esp isoflurane, aminoglycosides, antiarrhythmic) |
|
|
Term
| blocks ACh, produces surmountable blockade at skeletal muscle endplate, reversed by cholinesterase inhibitors |
|
Definition
| nondepolarizing type antagonists (includes all skeletal relaxants except succinylcholine) |
|
|
Term
| most likely to cauase histamine release (causing hypotension), long duration of action |
|
Definition
|
|
Term
| nondepolarizing agent w/ short duration of action |
|
Definition
|
|
Term
| agent blocking muscarinic receptors (causes increased HR, CO) |
|
Definition
|
|
Term
| agent that undergoes hoffman elimination |
|
Definition
|
|
Term
| only depolarizing blocker, causes continuous depolarization resulting in muscle relaxation/paralysis, causes post-op muscle pain, myoglobinuria |
|
Definition
|
|
Term
| effects of cholinesterase inhibitors on paralysis of succinylcholine |
|
Definition
| phase I - worsens paralysis; phase II - reverses succinylcholine blockade |
|
|
