Term
Lipid types:
1. Triglycerides
2. Phospholipids
3. Steroids |
|
Definition
1. Triglycerides: Store fat
2. Phospholipids: Plasma membrane
3. Steroids: Cholesterol (Builds Vit. D, bile, cortisol) |
|
|
Term
Lipoprotein roles:
1. HDL
2. LDL
3. VLDL |
|
Definition
1. HDL: GOOD; transports chol from tissue
2. LDL: BAD; Chol to tissue (atheroscler)
3. VLDL: BAD; Becomes LDL |
|
|
Term
Lab levels:
1. Total Chol
2. LDL
3. HDL
4. Trigs |
|
Definition
1. Total Chol: <200
2. LDL: <160
3. HDL: 40-60
4. Trigs: <150
*LDL: <100 if heart disease, <130 if 1/2 risks |
|
|
Term
|
Definition
| Lower cholest synthesis and increases LDL receptors (excrete LDL feces) |
|
|
Term
| Statin considerations (6) |
|
Definition
1. Preg cat X: Good BC!
2. Contra w/ alcoholism, liver D/O (D/C if LFT >3x normal)
3. Bedtime (chol high) except Lipitor
4. Increase H20 2-3L, take with food
5. NO grapefruit
6. Renal fail d/t Myalgia, myopathy, rhabdo |
|
|
Term
|
Definition
Blocks S. int. chol absorption, excrete in feces
Lowers LDL/trigs, increases HDL
Used w/ statins |
|
|
Term
|
Definition
|
|
Term
|
Definition
Questran, Colestid, Welchol
Bind w/ bile, lg resin molecule in s. intestine, excrete thru feces
Otherwise same as statins |
|
|
Term
|
Definition
Resin clogs (constipation)
Bleed D/O (Vit. K malab, ADEK)
1h b4 or 4-6h after meds (or will lower other meds absorption) |
|
|
Term
|
Definition
Completely mix powder (mucosal irritant)
6 oz. H20, milk, fruit juice, soup, pulpy fruit
1 mo: Max Fx |
|
|
Term
|
Definition
Stops free fatty acid release from adipose (VLDL)
Low dose: 25 mg/d (Vit. B)
High dose: 2-3 g/d (Lower chol) |
|
|
Term
|
Definition
1. 1 mo for Fx
2. Pre-tx w/ ASA/Benadryl to reduce flush/hot flash
3. Hyperglycemia, hyperuricemia, hepatotox
4. W/ food @ bedtime
5. Contra: Liver D/O, pregnancy |
|
|
Term
| Fibric acid derivatives (Lopid) |
|
Definition
Lowers serum trigs
Drug choice for triglyceridemia
Increases anticoag effects |
|
|
Term
|
Definition
Lowers trigs
May increase LDL/VLDL
Increases bleeding times |
|
|
