Term
| 4 forms of sleep disorders: |
|
Definition
1. insomnia
2. RLS
3. sleep apnea
4. narcolepsy |
|
|
Term
| 4 general etiologies of insomnia: |
|
Definition
1. situational
2. medical
3. psychiatric
4. pharmacologically induced |
|
|
Term
| diagnostic criteria for insomnia: |
|
Definition
1. sx present for >1month
2. epworth sleepiness scale
3. 2wk sleep log |
|
|
Term
| most effective tx for insomnia: |
|
Definition
| combined sleep hygiene/behavioral interventions and drug therapy |
|
|
Term
| 4 perscription med for insomnia: |
|
Definition
1. BZO hypnotics
2. non-BZO hypnotics
3. sedating antidepressants
4. melatonin agonists |
|
|
Term
|
Definition
1. antihistamines
2. melatonin |
|
|
Term
| most commonly prescribed therapy for insomnia: |
|
Definition
|
|
Term
|
Definition
1. triazoLAM
2. EstrazoLAM
3. TemazePAM
4. LorazePAM
5. FlurazePAM
6. QuazePAM |
|
|
Term
|
Definition
| bind to GABA receptors in CNS |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| BZO that causes rebound insomnia: |
|
Definition
|
|
Term
| 4 adverse effects of BZO: |
|
Definition
1. hangover
2. tolerance
3. amnesia
4. other CNS effects |
|
|
Term
|
Definition
| initiating and maintaining sleep |
|
|
Term
| which BZO only initiates sleep and does not maintain sleep: |
|
Definition
|
|
Term
|
Definition
1. elderly
2. Hx substance abuse
3. concominant anxiolytic therapy |
|
|
Term
| benefits of non-BZO hypnotics over BZOs: |
|
Definition
| 1. efficacy comparable w less abuse/tolerance/dependence potential |
|
|
Term
|
Definition
1. Zolpidem (ambien)
2. Zolpidem ER
3. Zaleplon (sonata)
4. Eszopiclone (lunesta) |
|
|
Term
| which non-BZO hypnotic has a choice btwn low dose for sleep onset and high dose to maintain sleep? |
|
Definition
|
|
Term
| which effects fo non-BZO lack that BZOs have: |
|
Definition
1. anxiolytic
2. muscle relaxant
3. anticonvulsant properties |
|
|
Term
| 4 adverse effects of Non-BZO hypnotics: |
|
Definition
1. dizziness
2. HA
3. amnesia
4. sleep walking |
|
|
Term
| non-BZO used for initiating sleep: 3 |
|
Definition
1. zolpidem (ambien)
2. zaleplon (sonata)
3. lunesta |
|
|
Term
| non-BZO that maintain sleep: |
|
Definition
|
|
Term
|
Definition
| elderly - initiate at lower doses |
|
|
Term
| indications for sedating antidepressants:4 |
|
Definition
1. intolerance to BZO/non-BZO
2. Hx of depression
3. neuropathic pain
4. Hx substance abuse |
|
|
Term
| 3 sedating antidepressants: |
|
Definition
1. trazedone
2. amitriptyline
3. mirtazepine |
|
|
Term
| sedating AD that causes priapism |
|
Definition
|
|
Term
| name the melatonin receptor agonist: |
|
Definition
|
|
Term
| 5 adverse effects of MRA ramelteon: |
|
Definition
1. anaphylactic rxns
2. amnesia
3. psychiatric illness/behavior
4. dizziness/fatigue
5. altered testosterone/prolactin |
|
|
Term
|
Definition
1. diphenhydramine
2. doxylamine |
|
|
Term
| 4 adverse effects from OTC meds for sleep: |
|
Definition
1. anticholinergic
2. dizziness
3. hangover
4. daytime drowsiness |
|
|
Term
| OTC cause initation or maintenance of sleep? |
|
Definition
|
|
Term
| 3 meds recommended for pts w hx of substance abuse: |
|
Definition
1. amitrityline
2. trazedone
3. mirtazepine |
|
|
Term
| Avoid these 3 in the elderly: |
|
Definition
1. sedating ADs
2. diphenhydramine
3. long acting BZO |
|
|
Term
| combination recommended for tx failure: |
|
Definition
| BZO or BzRA + Sedating AD |
|
|
Term
|
Definition
|
|
Term
| 10 drugs that initiate sleep: |
|
Definition
1. BZOs
2. ambien
3. sonata
4. lunesta
5. trazedone
6. anitriptyline
7. ramelteon
8. diphenhydramine
9. doxylamine
10. melatonin |
|
|
Term
| 5 drugs that maintain sleep: |
|
Definition
1. BZO
2. Ambien CR
3. Lunesta
4. trazedone
5. amitriptyline |
|
|
