Shared Flashcard Set

Details

Med Pharm 4/2 Sedative Hypnotics
Sedative hypnotics and anti-anxiety drugs
6
Pharmacology
Professional
12/26/2013

Additional Pharmacology Flashcards

 


 

Cards

Term
Midazolam (Versed)
Definition

Benzodiazepine

Use: brief surgical procedures; sometimes used for seizures refractory to other medications; may be given to children pre sx

Causes anterograde amnesia

Term
Eszopiclone (Lunesta®)
Definition

Mechanism: competes for benzo (all subtypes) receptor, separate from barbiturate and EtOH receptors

Uses: long term treatment of insomnia

Term
Zolpidem (Ambien®)
Definition

Sedative hypnotic

Mechanism: NOT BENZO but binds BZ1 subtype receptor, facilitate GABA inhibition, leading only to sedation (not the other effects); short half life

Use: short term insomniaFDA halved dose for women

Side effects: Worst for sleep related behaviors, rebound insomnia, sleepwalking, drowsiness/dizziness

Other drugs: Zaleplon (Sonata®

 

Term
Ramelteon (RozeremTM)
Definition

Mechanism: Melatonin agonist, regulates and maintains circadian rhythms

Actions: shortens delay to sleep onset

Contraindications: Sever liver disease due to slower metabolism

Term
Chloral hydrate (Noctec®)
Definition

Sedative hypnotic (nursing homes)

Uses: insomnia, conscious pediatric dental procedurer

Side effects: low margin of safety (resp and vasomotor depression), long term can cause liver damage+ fatal intoxication; 

Term
Diphenhydramine (Benadryl®)
Definition

Antihistamine- 1st gen

Use- occasional insomnia for benzo and EtOH addicts

Supporting users have an ad free experience!