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Pharm-Parrish Toxicology
antidotes, etc.
18
Medical
Graduate
08/06/2008

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Cards

Term
antidote for cholinesterase inhibitor
& mechanism
Definition
atropine
blocks muscarinic receptors
Term
Antidote for venom & mechanism
Definition
antivenin
immunological binding to toxicant
Term
Toxicant for antidote atropine
& mechanism of atropine
Definition
cholinesterase inhibitor
blocks muscarinic receptor
Term
antidote for cyanide & mech.
Definition
cyanide kit (na nitrite, na thiosulfate)
induction of methemoglobinemia, cyanide binds preferentially to metHb
Term
Na nitrite & thiosulfate--antidote for what? & mech.
Definition
cyanide
induction of methemoglobinemia, cyanide binds preferentially to metHb
Term
Digoxin antidote & mech.
Definition
Digoxin antibodies
immunological binding to toxicant
Term
Antidote for metals & mech.
Definition
Chelators
binding of metal & subsequent excretion in urine
Term
antidote for methanol, ethylene glycol
& mech.
Definition
ethanol
competition for alcohol Dehydrogenase
Term
Ethanol antidote for what? & mech.
Definition
methanol, ethylene glycol
competition for alcohol Dehydrogenase
Term
acetaminophen-antidote? & mech?
Definition
N-acetylcysteine
provides sulfhydryl groups to detoxify reactive metabolite
Term
N-acetylcysteine antidote for what?
and mech?
Definition
acetaminophen; provides sulfhydryl groups to detoxify reactive metabolite
Term
Opiates antidote & mech
Definition
Naloxone; blockade of opiate receptors
Term
naloxone antidote for what? and mech?
Definition
opiates, blockade of opiates receptor
Term
carbon monoxide antidote? and mech?
Definition
oxygen, in high concentrations displaces Co molecules from carboxyHb
Term
Isoniazid antidote & mech.
Definition
Pyridoxine HCl, competitively reverses isoniazid effect by providing substitute for pyridoxine kinase inhibited by isoniazid
Term
Pyridoxine HCl antidote for what?
& mech?
Definition
Isoniazid
competitively reverses isoniazid effect by providing substitute for pyridoxine kinase inhibited by isoniazid
Term
Antidote for benzodiazepines & its mechanism.
Definition
Flumazenil
blockade of benzodiazepines receptor
Term
flumazenil antidote for what?
Definition
benzodiazepines
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