Term
| Which drugs are considered NRTIs (Nucleoside Reverse Transcriptase Inhibitors)? |
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Definition
Zidovudine (AZT)
Didanosine (ddI)
Zalcitabine (ddC)
Lamivudine (3TC)
Stavudine (d4T)
Emtrictabine (FTC)
Abacavir |
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Term
| What are NRTIs used in the treatment of? |
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Definition
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Term
| What is Lamivudine (an NRTI) used in the treatment of? |
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Definition
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Term
| Which drug used to treat HIV has a SE of megaloblastic anemia? |
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Definition
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Term
| Which drug used to treat HIV has a SE of pancreatitis? |
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Definition
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Term
| Which drug when used in the treatment of HIV pos pregnant women and in neonates with HIV + mothers, has been shown to significantly reduce the risk of vertical transmission (from mother to child)? |
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Definition
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Term
| Which drug used to treat HIV, can cause lactic acidosis? |
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Definition
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Term
| Which drugs used to treat HIV can cause peripheral neuropathies? |
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Definition
Zalcitabine (ddC)
Stavudine (d4T) |
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Term
| Which drugs are considered Nucleotide Analog Reverse Transcriptase Inhibitors? |
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Definition
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Term
| What do Tenofovir and Adefovir treat? |
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Definition
HIV Infections
Adefovir treats Hep B infections as well |
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Term
| A 36y/o HIV + male presents to the clinic with epigastric pain that is sharp and radiates to his back. He states that he has been compliant with his meds. His labs indicate a markedly elevated level of lipase. What condition do you suspect and which drug do you believe is the underlying cause? |
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Definition
| Drug Induced Pancreatitis; Didanosine (ddI) |
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Term
| Which drugs are considered NNRTI's? |
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Definition
| Nevirapine, Efavirenz, Delaviridine |
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Term
| Which retroviral drug causes SE including CNS disturbances including insomnia, dizziness, delusions, and nightmares? |
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Definition
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Term
| Which anti-retroviral has SE including induction of the CYP 450 system (OCs, Warfarin, Metronidazole, Ketoconazole), SJS, and fulminant hepatitis? |
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Definition
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Term
| What are NNRTIs used in the treatment of? |
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Definition
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Term
| A 36 y/o HIV male pt presents with c/o having vivid nightmares and delusional thoughts during the day. His CD4 count in WNL and his viral load is nearly undetectable. Which anti-retroviral can cause these complaints that the pt presented with as a SE? |
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Definition
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Term
| What are Protease Inhibitors used to treat? |
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Definition
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Term
| Which drug class causes an altered distribution of body fat (buffalo hump or increased truncal obesity), insulin resistance, and hyperlipidemia? |
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Definition
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Term
| Which protease inhibitor has been shown to inhibit the cytochrome P-450 system leading to increased levels of certain drugs? Which drugs would this action affect? |
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Definition
Ritonavir
Ketoconazole, Rifampin, Erythromycin, anti-arrhythmic agents, benzos, clozapine, fluoxetine and haloperidol |
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Term
| An HIV + female presents with complaint of increasing waistline, despite dieting. On physical exam you notice a collection of fat above her C7 - T4 area When you run tests her triglyceride levels and cholesterol levels are elevated. What HIV med can cause these cushing-like SE? |
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Definition
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Term
| Which drug is used to HSV 1 and 2? |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| Which drugs are similar to Acyclovir? |
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Definition
| Valciclovir, Famciclovir, or Penciclovir |
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Term
| Which drug is effective against VZV? |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| Which drug is effective against EBV |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| Which drug is used to treat genital herpes? |
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Definition
|
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Term
| What drug is used to treat herpes encephalitis? |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| What drug is used to treat an acute VZV infection? |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| What drug is used to treat oral hairy leukoplakia (associated with an EBV infection)? |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| Which anti-viral causes SE including neurotoxicity that can cause tremor or delirium, nephrotoxicity (forming crystals in the urinary tract) and GI upset? |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| A pt presents with painful lesions on their genitalia and admits to a hx of unprotected sex with several different partners over the past several months. On physical exam you observe a vesicular lesion on the pts genitalia. What med should you use to treat this pt? |
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Definition
| Acyclovir (Valciclovir, Famciclovir, or Penciclovir) |
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Term
| Which med is used to treat CMV infections, especially CMV retinitis seen in AIDS pts? |
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Definition
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Term
| Which anti-viral can cause Pancytopenia, seizures, HA and nephrotoxicity? |
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Definition
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Term
| Which drug can be used as a second-line treatment for CMV retinitis and other CMV infections? |
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Definition
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Term
| What drug can be used in the treatment of acyclovir-resistant HSV and VSV infections? |
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Definition
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Term
| What is the major SE of Foscarnet? |
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Definition
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Term
| A 46 y/o pt presents with a c/o progressive decreased visual acuity and loss of peripheral vision. The pt has a hx of AIDS. The serum studies demonstrate the presence of CMV. What drug should you use as a first-line tx for this condition? |
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Definition
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Term
| What drug is similar to Amantadine? |
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Definition
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Term
| Which drug has been shown to stimulate the release of Dopamine from the neurons of the nigra striatum? |
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Definition
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Term
| Which drug is used to reduce the duration of influenza A symptoms, as well as an influenza prophylaxis in elderly and immunocompromised pts? |
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Definition
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Term
| Which drug is used in the treatment and prophylaxis of both Influenza A and B? |
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Definition
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Term
| Which anti-viral can be used in the treatment of Parkinson's disease? |
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Definition
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Term
| Which anti-viral drugs can cause CNS SE including ataxia, slurred speech, dizziness and GI upset? |
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Definition
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Term
| A elderly man presents with c/o malaise, HA, congestion, and weakness that began 24 hrs ago. He reports that his grandson came to visit him several days ago, but his mother had to pick him up early, as he became sick. The boy was taken to the clinic and was diagnosed with the flu. On physical exam cervical lymphadenopathy is present as well as a fever of 101.7F. Which med would you prescribe to this pt to help reduce the symptoms and duration of this condition? |
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Definition
Amantadine, (DOC)
Rimantadine or Zanamivir OR Ribavirin |
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Term
| What drug is used to treat RSV bronchiolitis and other RSV infections? |
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Definition
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Term
| Which anti-viral can be used to treat a Hep C infection? |
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Definition
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Term
| Which anti-viral has SE including Hemolytic anemia, elevated bilirubin levels and is teratogenic? |
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Definition
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Term
| In which pts is Ribavirin contraindicated in? |
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Definition
| Prego pts and those with renal insufficiency |
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Term
| Which anti-viral can be used to treat hep B? |
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Definition
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Term
| A 6-month old infant presents to the ER with a 3-day hx of rhinitis, non-productive cough, tachypnea, and fever. On physical exam his RR is 42 bpm, and his O2 sat is 90% on Room air. Subcostal retractions and coarse breath sounds are present bilaterally. Lab studies reveal a pos RSV test. What med should you start this pt on? |
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Definition
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