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| potassium-sparing diuretic |
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potassium-sparing diuretic
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potassium-sparing diuretic
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potassium-sparing diuretic
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| carbonic anhydrase inhibitor |
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| ... diuretics prevent water reabsorption |
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| water is always ... reabsorbed in the kidneys |
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| ...-...% of blood plasma entering the kidneys if filtered into the ... |
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| the kidney has .. functional zones which are ... |
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5
proximal convoluted tubule
descending loop of henle
ascending loop of henle
distal convoluted tubule
collecting tubule and duct |
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| almost all glucose, bicarbonate, and amino acids along with ... Na reabsorbed in the ... |
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2/3
proximal convoluted tubule |
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| CAIs work in the ..., which is also the site of organic acid and base secretory systems |
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| proximal convoluted tubule |
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| water reabsorption continues in descending loop of henle, which results in tubular fluid with a ... increase in salt concentration |
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| cells in the ... are impermeable to water |
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ascending loop of henle
distal convoluted tubule |
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| considered a diluting region (major site of ... reabsorption), the ... is where active reabsorption of electrolytes occurs, ... diuretics work here |
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salt
ascending loop of henle
loop |
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| thiazide diuretics work in the ... |
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| 10% of sodium chloride is reabsorbed in the ... |
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| in the collecting tubule and duct, ... and .. are excreted and ... is reabsorbed |
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| in premenstrual edema and cyrrhosis of the liver, you can get ... |
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| endematous states lead to ... |
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| ... diuretics can help hypercalcemia by increasing ... |
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| polyuria and polydipsia are treated with ..., with reduced ... causing a drop in ... |
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diuretics
plasma volume
glomerular filtration rate |
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| ... diuretics are the most widely used, are ... derivatives, are better than ..., and affect the ... tubule |
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thiazide
sulfonamide
CAIs
distal |
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| thiazide diuretics inhibit ..., which increases concentration of ... and ... in the tubular fluid |
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Na/Cl co-transporter
Na
Cl |
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| ... are the only diuretics that result in hyperosmolar urine |
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| t/f thiazide diuretics help you if you have hypercalciuria |
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| true, results in decreased urinary calcium excretion |
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| some adverse effects of thiazide diuretics are ... depletion, hypo..., and hyper... |
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Definition
--potassium--bad with digoxin--could give ventricular arrhythmias
--natremia, decreased Na
--uricemia, increased serum uric acid can result in gout |
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| ... are the diuretics that have the highest efficacy |
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| loop diuretics inhibit ..., and increase ... synthesis, but ... can reduce the effect |
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Na/K/2Cl cotransporter
prostaglandin
NSAIDs |
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| ... diuretics are the drug of choice for reducing acute pulmonary edema of heart failure, is useful in ... situations, and is useful in treatment of ... and ... |
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loop
emergency
hypercalcemia
hyperkalemia |
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| ... diuretics adverse effects can be ototoxicity or acute hypovolemia |
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| loop diuretics increase urinary excretion of what 4 things? |
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| potassium-sparing diuretics act in the ..., and inhibit ... reabsorption and ... excretion, and their major use of treatment of ... |
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collecting tubule
Na
K
HTN |
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| ... antagonists can prevent production of proteins that stimulate Na/K exchange sites of the collecting tubules |
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| aldosterone antagonists are metabolized by ... and are highly/not bound |
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P450 system into active metabolite
highly |
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| ... chemically resemble some sex hormones |
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| ... are not useful in patients that don't have increased levels of aldosterone |
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| in addison's disease, there is no increased levels of .. |
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| ... diuretics have diuretic activity even in Addison's disease, and are/are not efficacious when used alone |
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potassium-sparing
are not |
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| carbonic anhydrase catalyzes reaction to form ... |
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| ... and ... are the CAIs that can topically treat glaucoma |
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| ... can help in mountain sickness if given nightly for 5 days before climb |
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| metabolic acidosis is an adverse effect of this diuretic |
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| CAI, because it inhibits production of bicarbonate |
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| acetazolamide has major increased urinary excretion of ... and ... |
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bicarbonate
potassium--possible depletion |
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| ... diuretics are filtered through the glomerulus and carry water with them, can be used to treat increased ... pressure |
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