Term
|
Definition
-high local concentration (not systemic)
-used for glaucoma, corneal dz, conjunctival dz, anterior uveitis
-must be well tolerated, stable, readily release active ingredient (gets washed away quick!) |
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|
Term
| When to use systemic drugs |
|
Definition
-deep, intraocular penetration is needed
-additional efficacy is needed with topicals
-globe is perforated (NO topical meds!) |
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|
Term
| When to use subconjunctival drugs |
|
Definition
-used in difficult to tx animals
-once in, can't take them away! |
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Term
|
Definition
-ointments are good for when longer contact time is needed
-NEVER use if eye is perforated |
|
|
Term
|
Definition
Eyedrops: 1 drop
-wait 5 MIN in between drops
Ointment: 1/4" strip |
|
|
Term
Antimicrobials
Bacitracin/Neo/Poly |
|
Definition
-broad spectrum
-bacteria slow to develop resistance
-1st choice for PROPHYLAXIS with corneal ulcers
- |
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|
Term
Antimicrobials
Chloramphenicol |
|
Definition
| -gram + corneal infections |
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|
Term
|
Definition
-IV prep is diluted to make 33g/mL
-gram + corneal infections |
|
|
Term
Antimicrobials
Tobramycin/Gentamicin |
|
Definition
-gram - corneal infections
-Pseudomonas less likely to develop resistance to tobramycin than gentamicin |
|
|
Term
Antimicrobials
Ciprofloxacin |
|
Definition
-Used for gram + and gram - infections
-ONLY use for infections
-good corneal penetration and drug levels |
|
|
Term
Antimicrobials
Oxytetracycline |
|
Definition
-drug of choice in cats with conjunctival infections
-Chlamydophila
-Mycoplasma |
|
|
Term
Anti-inflammatories
Corticosteroids |
|
Definition
Hydrocortisone
-used for minor conjunctival disease such as allergic conjunctivitis |
|
|
Term
Anti-inflammatories
Prednisolone Acetate and Dex |
|
Definition
| -Used for severe conjunctival or corneal disease and for anterior uveitis |
|
|
Term
|
Definition
-can be used for when corneal ulcers are present
-topically or systemically in horses |
|
|
Term
Immunosuppressives
Tacrolimus/CsA |
|
Definition
-suppress T cell helper activity
-increase tear production
-typically topical |
|
|
Term
|
Definition
-indirect parasympatholytic drug
-causes dilation of pupil
-paralysis of ciliary body (pain relief)
-long acting
-used in corneal ulceration or anterior uveitis |
|
|
Term
|
Definition
-indirect parasympatholytic
-facilitate fundus exam
-dilates in 15 min, up to 8 hrs |
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