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Pharm II unit 1
Drug compatibility
18
Nursing
Undergraduate 1
09/04/2011

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Cards

Term
What are the 3 types of drug compatibility?
Definition
Chemical, physical and  therapeutic compatibility
Term
How menny types of compatibility must you check before administering an IV?
Definition
you must check all 3
Term

An incompatibility results when:

 

 

Definition
two or more substences react,  interact or change the normal activity of the substence.
Term
When are incompatibilitys most likly to occur?
Definition

when seveal drugs are added to make a mixture

 

if soultions are given one after another using qme IV tubing

 

a drug is mixed in wrong substence

 

reacts withanother drugs preservatives

Term
A physical incompatibility is also called-
Definition
a pharmaceutical incompatibility
Term
What are the two types of physical incompatibility?
Definition
Insolubility and Absorption
Term
When does insolubility occur?
Definition
When a drug is added to an inappropriate fluid solution.
Term
What are the signs of insolubility?
Definition
Visible precipitation, haze, gas bubbles, and cloudiness.
Term
What prevents microscopic precipitates from entering the blood stream?
Definition
The use of micropore filters.
Term
What electrolite increases the risk of forming a precipitate when mixed with other drugs?
Definition
Calcium
Term

True or False

 

If you see precipitates in an IV it is ok to administer it if you have a micropore filter.

Definition

False

 

If you see the precipitates, it is no longer microscopic.

Term
Do not mix drugs prepared in special ___________ with other drugs.
Definition
Diluents
Term
When administering a series of medications you must prepare each drug in __________?
Definition

A Separate syringe

 

this will lessen the possibility of precipitation

Term
What does insolubility result from?
Definition

They use incorrect solution to reconstitute a drug.

 

Follow all manufacturers instructions.

Term
What is therapeutic incompatibility?
Definition
An undesirable effect occurring as a result from two or more drugs being given concurrently.
Term
As a result of therapeutic incompatibility is a drugs therapeutic response increased or decreased?
Definition
Either can occur.
Term
What is a chemical incompatibility?
Definition
A reaction between drugs with other drugs or solutions which result in alterations of the integrity and potency of the drug.
Term
What is the most common cause of chemical incompatibility?
Definition
A reaction between acid and alkaline drugs or solutions resulting in a pH level that is unstable for one of the drugs.
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