Term
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Definition
Strong Opioid Agonist
PROTOTYPE |
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Term
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Definition
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Term
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Definition
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Term
| Fentanyl (Actig, Duragesic) |
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Oxycodone (Oxycontin, Percoset) |
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Definition
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Term
| Propoxyphene (Darvon, Darvocet) |
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Definition
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Term
| Buprenorphine (Buprenex, Suboxone) |
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Definition
| Mixed Opoid Agonist/Antagonist |
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Term
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Definition
| Mixed Opoid Agonist/Antagonist |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| ibuprofen (advil, motrin) |
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Definition
| NSAID (propionic acid derivative) |
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Term
| naproxen (naprosyn, aleve) |
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Definition
| NSAID (propionic acid derivative) |
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Term
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Definition
| NSAID (acetic acid derivative) |
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Term
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Definition
| NSAID (acetic acid derivative) |
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Term
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Definition
| NSAID (oxicam derivative) |
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Term
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Definition
| NSAID (oxicam derivative) |
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Term
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Definition
NSAID (heteroaryl acetic acid)
(IV)(IM)(PO) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
DMARD
(PO)(IV)(IM)
DHFR Inhibitor (immunosuppressive) |
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Term
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Definition
DMARD
(PO)
DHOOH Inhibitor (pyradine synthesis) |
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Term
| hydroxychloroquine (Plaquenil) |
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Definition
DMARD
(PO)
Dendritic TLR Inhibitor |
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Term
| sulfasalazine (Azulfidine) |
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Definition
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Term
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Definition
BIOLOGIC DMARD
(IV)
TNF-α inhibitor |
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Term
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Definition
BIOLOGIC DMARD
(IV)
TNF-α inhibitor |
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Term
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Definition
BIOLOGIC DMARD
(SQ)
IL-1 antagonist |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| probenecid, sulfinpyrazone |
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Definition
uricosuric agents FOR GOUT
(IV) |
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Term
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Definition
PO, IV, Topical
(HSV, VZ, HZ) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Topical
(herpes labialis) |
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Term
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Definition
Topical: Eye drops
(HSV keratoconjunctivitis, recurrent epithelial keratitis) |
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Term
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Definition
Topical: Eye ointment
(HSV keratoconjunctivitis, recurrent epithelial keratitis) |
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Term
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Definition
Topical: Eye drops
(HSV-1 Keratitis) |
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Term
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Definition
PO, IV, Patch
PROTOTYPE
(CMV retinitis/colitis/esophagitis) |
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Term
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Definition
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Term
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Definition
IV
(Broad HSV, ganciclovir-R CMV) |
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Term
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Definition
IV (eyeball)
(CMV retinitis (AIDS)) |
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Term
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Definition
IV
(Last resort drug to treat all CMV and R-CMV) |
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Term
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Definition
PO
RNA ANTIVIRAL (Influenza A) |
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Term
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Definition
PO
RNA ANTIVIRAL (Influenza A) |
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Term
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Definition
PO
Neuraminidase Inhibitors
(Influenza A or B) |
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Term
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Definition
Inhaled
Neuraminidase Inhibitors
(Influenza A or B) |
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Term
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Definition
IM
MIXED MOA RESP. INFECT ANTIVIRAL
(RSV) |
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Term
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Definition
PO, IV, inhaled
MIXED MOA RESP. INFECT ANTIVIRAL
( RSV [Hep C, Broad spectrum] ) |
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Term
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Definition
PO
ANTIVIRAL COMBO
(Hep C) |
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Term
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Definition
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Term
| Zidovudine (Retrovir, AZT) |
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Definition
NRTI
dose-limiting bone marrow suppression, anemia, neutropenia drug interaction w/ ganciclovir |
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Term
| Zalcitabine (ddc) (HIVID) |
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Definition
NRTI
use in advance AIDS and in combo w/ AZT peripheral neuropathy |
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Term
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Definition
NRTI
peripheral neuropathy, pancreatitis, lactic acidosis cannot be used w/ AZT |
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Term
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Definition
NRTI
rash, severe/fatal hypersensitivity rxn no bone marrow suppression
NOT ON OBJECTIVES FOR NRTI'S
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Term
| Lamivudine (3TC) (Epivir) |
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Definition
NRTI
minimal txicity sometimes w/ Hep B to prevent infection combivir = lamivudine + AZT (used in PEP) |
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Term
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Definition
NRTI
combo drug of non-food dependent drugs
NOT ON OBJECTIVES FOR NRTI'S |
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Term
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Definition
NRTI
dose-limiting pancreatitis (can be fatal), peripheral neuropathy made w/ buffering agent to prevent HCL degredation |
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Term
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Definition
NRTI
Hep B drug
requires L-carnitine supplementation nephrotoxic no bone marrow suppression
NOT ON OBJECTIVES FOR NRTI'S |
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Term
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Definition
NRTI
admosine nucleotide analog / chain termination
pts who have failed on other HIV drugs slow resistance to drug
NOT ON OBJECTIVES FOR NRTI'S |
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Term
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Definition
NRTI
cytidine neucleoside analog
skin hyperpigmentation of the soles and palms
NOT ON OBJECTIVES FOR NRTI'S |
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Term
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Definition
NNRTI
DMMS inducer
penetrates CNS & causes CNS s/e no preggers |
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Term
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Definition
NNRTI
DMMS inducer
alternative to AZT prevention of transmission during preggers |
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Term
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Definition
NNRTI
resistant HIV
NOT ON OBJECTIVES FOR NNRTI'S |
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Term
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Definition
NNRTI
DMMS inhibitor
NOT ON OBJECTIVES FOR NNRTI'S |
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Term
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Definition
PI
potent drug, advanced disease strong inh of P450 good combo w/ saquiovir |
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Term
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Definition
PI
causes kidney stones, crystalluria |
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Term
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Definition
PI
PEP with combivir, zidovudine, lamivudine maternal dose during labor to dec. baby getting HIC x 50% |
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Term
Saquinavir-H (Invirase)
NOT ON OBJECTIVES |
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Definition
| PI only used w/ ritonavir hard tablet |
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Term
Saquinavir-S (Fortovase)
NOT ON OBJECTIVES |
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Definition
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Term
Amprenavir (Agenerase)
NOT ON OBJECTIVES |
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Definition
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Term
Kaletra (lopinavir/ritonvir)
NOT ON OBJECTIVES |
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Definition
| PI combo drug lipinavir + ritonavir |
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Term
Atazanavir (Reyataz)
NOT ON OBJECTIVES |
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Definition
PI
less inc in TG/chol, less liprodystrophy |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Platelet Inhibitors COX-1, inhibit PG synthesis, block TXA2 |
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Term
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Definition
Platelet Inhibitors
inhibits ADP, fibrinogen binding to platelets |
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Term
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Definition
Platelet Inhibitors
preferred drug, most widely used anti-platelet |
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Term
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Definition
Platelet Inhibitors
vasodilator, inc cAMP, dec platelet Ca
high-risk pts only |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| vitamin K, fresh frozen plasma |
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Definition
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Term
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Definition
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Term
| Streptokinase (Streptase) |
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Definition
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Term
| tissue plasminogen activator (t-PA) (Alteplase) |
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Definition
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Term
| aminocaproic acid (Amicar) |
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Definition
Coagulant
Plasminogen inhibitor |
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Term
| thrombin (Thrombogen, Thrombostat) |
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Definition
Coagulant
Thrombin stimulator |
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Term
| gelatin sponge (Gelfoam), film (Gelfilm), cellulose (Surgicel) |
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Definition
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Term
| amphotericin B (Fungizone) |
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Definition
IV
Broad spectrum, invasive/progressive potentially fatal fungal infections |
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Term
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Definition
(PO)
crytococcal meningitis, systemic crytococcal/candidal infections *used in combo w/ AmpB (synergism), resistance when used alone |
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Term
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Definition
(PO) IMANDIAZOLE
mucocutaneous fungal infections |
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Term
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Definition
(PO) TRIAZOLE
coccidioidal meningitis**DOC, serious/systemic candidiasis |
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Term
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Definition
(PO)(IV) TRIAZOLE
broad spectrum, histoplasmosis, no CNS infections |
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Term
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Definition
(IV) ECHINOCANDINS
Aspergillus and candida only; candida esophagitis, invasive aspergillosis, R-amp B or itraconazole |
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Term
| griseofulvin (Grifulvin, Gris-Peg) |
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Definition
(PO)
ringworm/tineas nail infections, dermatophytic |
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Term
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Definition
TOPICAL/SWISH & SPIT
candidiasis |
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Term
| miconazole (Monistat, Micatin) |
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Definition
TOPICAL/SUPPOSITORY
IMADIAZOLE candidiasis, ringworm |
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Term
| clotrimazole (Mycelex Troches, Lotrimin) |
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Definition
TOPICAL IMADIAZOLE
candidiasis |
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Term
|
Definition
TOPICAL SYNTHETIC ALLYLAMINE
dermatophytoses, onychomycoses**DOC, candida albicans |
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