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Pharm Herbal
KYCOM Block 16
31
Pharmacology
Graduate
05/14/2014

Additional Pharmacology Flashcards

 


 

Cards

Term
FDA rules on herbs
Definition
FDA DOES NOT REQUIRE PROOF OF EFFICACY, SAFETY, OR QUALITY CONTROL
FDA HAS TO PRROVE ITS UNSAFE RATHER THAN PROVE ITS SAFE

can claim to benifits but not cure

NCCAM oversees herbs not really FDA
Term
how patients think about herbs
Definition
dont think doctors are for them
dont admit to talking them
dont realize 30% of drugs come from herbs
Term
possible harms of herbs and why
Definition
if it has enough power to cause benifit it can cause harm

variability between manufactures, batches, plants, potency

additives may be added and not listed

wrong part of plant could be picked (belladona poisoning, digitalis poisoning)

can have heavy metals
Term
why herbs dont have much research
Definition
controlled studies not profitable
studies not required
toxic effects seldom reported
Term
possible additives found in herbs that are dangerous
Definition
pesticides
non declaired drugs
added chemicals
heavy metals: Pb, Ar, Cadmium, Cu, Me
prednisone
testosterone
diazepam
Term
garlic: MOA, uses 5, SE 1
Definition
allin > allicin (sulfur) > inhibits HMG-CoA reductase and TXA2

tx: hyperlipidemia, HTN, decreases LDL, TG, plaque

SE: ANTICOAGULANT, WATCH OUT WITH WARFARIN
Term
ginko: sources 3, use 1
Definition
in flavonoids, sequiterpenes, terpenes
IMPROVE COGNITIVE FUNCTION
Term
echinacea: MOA, use, SE
Definition
activates NK cells and monocytes

INCREASE EFFECTS OF IMMUNE SYSTEM

HEPATOTOXICITY IF USED >8WKS
Term
soy: sources 4, use 1
Definition
in protein, isoflavones, fiber, omega-6-FA

TX HYPERLIPIDEMIA (DECREASES TG, LDL, CHOLESTEROL)
Term
saw palmetto: MOA, use
Definition
5-A-REDUCTASE INHIBITOR
TX SYMPTOMS OF BPH
Term
ginseng: MOA, use
Definition
sapones called ginsenoides
TX FATIGUE
Term
st. johns wart: MOA, use, SE
Definition
increases srtotonin
TX DEPRESSION
induces P450
Term
black cohosh: use
Definition
TX MENOPAUSE SYMPTOMS
Term
valerian: MOA, use
Definition
valernic acid
IMPROVES SLEEP QUALITY
Term
glucosamine and chondroitin: sources, use, 3 benifits
Definition
glucosamine is AA sugar
chondroitin is glycosaminoglycan

TX OSTEOARTHRITIS

DECREASES JOINT PAIN
INCREASES MOBILITY
INCREASES QUALITY OF LIFE
Term
creatinie: sources 2, use, 2 benifits
Definition
made from flycine and arginine in urea cycle
in meat and fish

EXERCISE PERFORMANCE

INCREASES MUSCLE MASS
STRENGTH IN SHORT PERFORMANCE
Term
use aloe
Definition
topical for burns
Term
use angelica 2
Definition
gynecologic disorders: post menopause, menstural discomfort
Term
bee polen use 3
Definition
allergies, asthma, impotence
Term
capsicum use
Definition
pain (capsaicin)
Term
coenzyme Q10 use 2
Definition
heart diseae
heart failure
Term
DHEA use
Definition
enhance immune system
Term
dong quai use 2
Definition
gynecological disorders: irregular mensturation, PMS
Term
gotu kola use 2
Definition
immune stimulant
antifertility
Term
horse chesnut use 2
Definition
vericose veins
hemorrhoids
Term
kava kava use 2
Definition
seizures
anxiety
Term
licorice use
Definition
peptic ulcer
Term
melatonin use 3
Definition
jet lag
sleep induction
cancer
Term
shark cartiladge use
Definition
cancer
Term
thoimbe use 2
Definition
aphrodisiac
male impotence
Term
medicines derived from plants
Definition
atropine
digoxin
cholchine
reserpine
quinine
vincristine
taxol
phygostigmine
ephedrine
cocaine
cslicylin
scopolamide
pnehylbutazone: NSAID, DC heavy metals
aminopyrine: NSAID, DC marrow toxicity
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