Term
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Definition
Works to dec. insulin output and inc the muscular sensitivity to insulin.
500 mg DID or 850 mg once a day |
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Term
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Definition
Drug of choice for T2DM, Many contraindications.
Adv: No Hypoglycemia or weight gain
Dis: Gi discomfort (take in slow dose), tastes like metal.
Works on liver to dec. glucose output and on muscles to inc. insulin sensitivity. |
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Term
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Definition
Thiazolidinedione
15 or 30 mg once daily.
Primarily inc. muscle sensitivity and secondary dec. glucose output.
Adv: no hypoglycemia and fav lipid effects.
Dis: adema and fluid retention, weight gain, heart failure, osteopenia |
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Term
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Definition
5 mg once a day.
Sulfonylurea: Incretin mimetic, stimulates the pancreas to release insulin.
Dis: hypoglycemia, weight gain |
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Term
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Definition
.5-2 mg before the meal
Glinide: Incretin mimetic (stimulate pancreas to release insulin).
Dis: weight gain, hypoglycemia (slight) |
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Term
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Definition
Alpha-Glucosidase Inhibitor
Delays carbohydrate absorption in small intestine (type II)
Dis: GI problems (gas, bloating, diarrhea).
Do not use oral sucrose. |
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Term
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Definition
Incretin Mimetic
5 mcg subqutaniously twice a day
Found in Gila Monster
Limits food intake and gastric emptying as well as postprandial glucagon if inappropriate.
Dis: Nausea, hypoglycemia, slows the extent and rate of absorption of other meds (meds taken 1 hour before exenatide) |
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Term
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Definition
Incretin Mimetic
Limits food intake, gastric emptying and postprandial glucagon.
Adv: weight loss
Dis: Nausea, hypoglycemia, slows the extent and rate of absorption of other meds (meds taken 1 hour before exenatide) |
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Term
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Definition
DPP-4 Inhibitor
100 mg by mouth once daily
Adv: No hypoglycemia
Dis: hypersensitivity, placebo esq, Nasopharyngitis, upper respiratory infection |
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Term
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Definition
Amylinomimetric
SubQ
Mimics Amylin which is secreted with insulin
Adv: weight loss, lower risk of hypoglycemia
Dis: severe hypoglycemia, nausea, vomiting, Meds need to be taken 1 hour before |
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Term
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Definition
6 tablets once daily
Unknown Mechanism
Adv: no hypoglycemia, favorable effects on lipis
Dis: may contraindications, constipation, many drug interactions (drugs should be admin 4 hours before taking this) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
Basal Insulin
Peak 4-10 hours, duration 10-16 hours |
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Term
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Definition
Basal Insulin
Peak: 6-8 Hours, duration: 6-23 hours |
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Term
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Definition
Basal Insulin
Peak: NONE, Duration: 24 Hours |
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