Isoniazid (INH) know this for sure

ethambutol

pyrazinamide(PZA)

Streptomycin

Used in combination with other meds

Drug of choice for TB

watch for probs with liver

liver fx needs to be assessed

contraindicated with liver disease

also used for prophylaxis for TB

Peripheral neuropathy- patient needs Vit B6

hepatotoxicity

Hepatitis, discoloration of urine and stools

Therapy up to 24 months

take meds as ordered, same time every day

They are contagious during initial period of illness

adequate nutrition and rest

do not consume alcohol

Check with physician before taking otc

INH and rifampin

another form of birth control will be needed

Pyridoxine

Candida albican

(oral fungal infection)

systemic- amphotericin B, caspofungin, fluconazole, ketoconazole

topical- clotrimazole, miconazole, nystatin

Neurotoxicity

Renal toxicity

potassium levels and mg levels

fever, chill, body aches

increase liver enzymes

GI upset

caution with liver and kidney probs

reduce severity of the infusion-related reactions, pretreatment with antipyretic, antihistamines, antiemetics, and corticosteroid may be given.

Use iv infusion pumps and the most distal veins possible

How should nystatin oral lozenges or troche should be taken

reduces duration of influenza A and B

treatment should begin within 2 days of onset of symptoms

abacavir, zidovudine, lamivudine

used in many combinations

-replacement therapy to make up for hormone def.

drug therap to produce a certain hormone response

diagnostic aids to determine hypofunction or hyper function of a specific hormonal funtion

stimulates cortisol

antiinflammatory effect

promotes renal retention of sodium, can result in edema and HTN

Diagnostic testing is required to identify this.

controls growth hormone

stimulates muscle growth such as dwarfism

octreotide(sandostatin)

given for tumors that may cause VIP which causes diahrrea.

This reduces the potentially life threatening hypotension that may occur with a carcinoid crisis.

treatment of diabetes insipidus.

Vasopressin: powerful vasoconstrictor used for hypotensive emergencies, GI bleeding, and pulseless cardiac arrest.

Desmopressin: used for does-dependent treatment of blood disorders; also for nocturnal enuresis.

IM,SC,IV, gel, resp forms

avoid vaccines

decrease K and Na intake

Levothyroxine- T4 synthetic

Liothyronine- synthetic T3

liotrix- synthetic T3 and T4 combined

Thyroid- desiccated (dried) animal thyroid gland

treats all three forms of hypothyroidism.

levothyroxine is preferred drug, effects are predictable

desired effect is euthyroid

cardiac dysrhythmia is the most significant adverse effect.

some other effects: tachy, palpitations, angina, htn, insomnia, tremors, headache, nausea, anxiet, etc...

Radioactive iodine for destroying the thyroid gland or surgery removal, which leads to lifelong thyroid hormone replacement.

-Antithyroid drugs: thioamid derivatives

methimazole(Tapazole)

propylthiouracil(PTU)

teatment should continue in pregnancy.

Fetal growth may be retarded if untreated

-adjust dosage every 4 weeks to keep TSH at lower end of normal range

How should antithyroid meds be taken?

better tolerated with food, but is better on an empty stomach.

give at the same time each day.

Never stop abruptly

Avoid eating foods high in iodine (seafood, soy sauce, tofu, iodized salt)

glucocorticoids: beclomethasone, fluticasone propionate, hydrocortisone, cortisone, methylprednisolone, prednisone

Mineralorcorticoid: fludrocortisone acetate

Adrenal steroid inhibitors: aminoglutethimide

adrenocortical def.

inflammation (usually)

copd, asthma

cerebral edema

rashes (itching)

organ transplants (decreases immune response)

by inhalation for control of steroid responsive bronchospastic states

Nasally for rhinitis and to prevent the recurrence of polyps.

topically for inflammations

Infections

cautious use in gastritis, relux, ulcers

diabetes, cardiac/renal/liver dysfunction

Metformin (Glucophage)

type 2 diabetics

-decreases production of glucose by the liver

-decrease intestinal absorption of glucose

-increase uptake of glucose by tissues

-do not increase insulin secretion from the pancreas( does not cause hypoglycemia)

Diagnostic test that use contrast dye, they cannot take this at this same time.

Primarily affects GI tract: abdominal bleeding, bloating, diarrhea, nausea

amaryl, glucotrol, diabeta, micronase

-can cause abdonminal issues

-increases insulin levels.

starlix, prandin

-similar to sulfonylureas

-increase insulin secretion from the pancreas.

pioglitazone, avandia

-also known as glitazones

-decrease insulin resistance

-can cause weight gain and edema

precose, glyset

-delayed absorption of glucose

-must be taken with meals to prevent excessive postprandial blood glucose elevations

-abdominal cramping, flatulence

has more to do with absorption of glucose

symlin

-slows gastric emptying(feel full longer)

-reduces hepatic glucose output

-subcut inj

-used when other drugs have not acheived adequate glucose control.

-take one hour before other meds

byetta, januvia

-increases insulin secretion from beta cells of the pancreas

-only used for type 2 diabetes

-exenatide: injection pen device

good drug for weight loss, hyperglycemia can occur

-check blood glucose lvls before giving

-usually given 30 min before meals

-alpha-glucosidase inhib are given with the first bite of each meal

-metformin is taken with meals to reduce GI effects

-metformin will need to be dc if the patient is to undergo studies with contrast dye because of possible renal effects.