Term
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Definition
| Study of adverse effects of agents (chemical, biological, or physical) on living system |
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Term
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Definition
| toxic substances produced by biological systems |
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Term
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Definition
| Toxic substances produced by human activities |
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Definition
"Toxicologic syndromes"
Group of signs and symptoms associated w/ specific toxic agent |
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Term
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Definition
| expected frequency of occurence of undesireable effect from exposure to chemical of physical agent |
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Term
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Definition
| ability of chemical agent to cause injury in given situation or setting |
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Term
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Definition
single exposure or
multiple exposures w/in 1-2 days |
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Term
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Definition
Continuous exposure or
Multiple exposures for longer than a few days
(1-3 months may be considered subchronic) |
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Term
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Definition
| Additive effect from exposure to 2 or more chemicals |
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Term
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Definition
Form Synergism-
a chemical itself has no effect, but it increases the toxicity of another |
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Term
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Definition
| Ratio btw toxic dose and and therapeutic dose |
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Term
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Definition
Airway-cleared of obstruction
Breathing- adequacy assessed, supported
Circulation- assess
Dextrose- given in pts w/ altered mental status |
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Term
| What should alcoholic or malnourished pts also be given |
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Definition
Thiamine
prevents Werneke's encephalopathy |
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Term
| What drug given if Opiod OD suspected |
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Definition
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Term
| What drug given for Benzodiazepine OD |
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Definition
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Term
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Definition
-Vitals
-Eyes
-Mouth
-Skin
-Abdomen
-Nervous System |
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Term
| What labs and x-rays done in poisoned pts |
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Definition
-ABG
-Electrolytes
-Renal Fxn test
-Serum Osmolality
-Electrocardiogram
-Xray |
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Term
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Definition
-Skin
-GI
emesis, gastric lavage, catharsis, activated charcoal |
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Term
| How enhance elimination of toxicants |
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Definition
-Change urinary pH
-dialysis
-Hemoperfusion |
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Term
| Mechanism Antidotes can employ |
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Definition
1. Bind to toxin and inactivate it
2. Block critical receptor
3. Change toxicant metabolism
4. Reverse biochemical damage |
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Term
| Snake or Spider envenomation |
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Definition
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Term
| Cholinesterase Inhibitors, muscarinic mushrooms, Beta Antagonists, digoxin and cardiac glycosides |
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Definition
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Term
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Definition
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Term
| Digoxine, Digitoxin, etc. |
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Definition
| Digoxin specific anti-body |
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Term
| Arsenic, mercury, gold, lead |
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Definition
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Term
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Definition
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Term
| Methanol and ethylene glycol |
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Definition
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Term
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Definition
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Term
| Carbon Monoxide, cyanide, hydrogen sulfide |
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Definition
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Definition
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Term
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Definition
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Term
| Organophosphate pesticides |
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Definition
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