Term
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Definition
- Competitive
- Long duration of aciton (2-3hr)
- Renal elimination; incr. t1/2 with renal disease
- little ganglionic blockade
- No histamine release
- Blocks muscarinic receptors (tachycardia)
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Term
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Definition
- Competitive
- Immediate duration (.5-1hr)
- Spontaneous degredation: enough to elim from body (temp, pH dependent)
- Also have hydrolysis, renal elimination; t1/2 is NOT increased with renal disease
- Little/no ganglionic blockade
- Promotes histamine release
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Term
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Definition
- Competitive
- Short duration of action (15m)
- Rapid hydrolysis; t1/2 is NOT increased with renal disease
- little/no ganglionic blockade
- promotes histamine release
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Term
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Definition
- Depolarizing NMJ blocker
- 2 ACh linked together; mimics ACh activity
- Resistant to AChE
- NOT pharmacologically reversible
- Rapid onset (1m), short duration (5m)
- Rapidly hydrolyzed
- Useful for rpaid and short lived NMJ blockade
- Some histamine release, no ganglionic blockade
- Hyperkalemia possible from sk mm K+ release
- AVOID WITH SOFT TISSUE DAMAGE/BURNS
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