Term
|
Definition
|
|
Term
| Which are used to against B. Fragilis and in triple antibiotic coverage |
|
Definition
| Cefmetazole and Cefoxitin |
|
|
Term
| Which are having additive affect against H.influenza and otitis infection |
|
Definition
| Cefamandole, Cefonicid, Cefaclor and Cefuroxime |
|
|
Term
| Which antibiotic is used to treat g(-) Klebsiella? |
|
Definition
| First and second generation of Cephalosporin |
|
|
Term
| Which antibiotic is used to treat Enterococcus or pseudomonas? |
|
Definition
| Neither first or second generation of Cephalosporin |
|
|
Term
| Which antibiotic is used to treat H. Influenza, primarily sinusitis and Lower respiratory infection, and otitis media? |
|
Definition
| First and second generation of cephalosporin |
|
|
Term
| Which antibiotic is used to treat Anaerobe? |
|
Definition
| Cefoxitin and Cefmetazole |
|
|
Term
| Which is used as an alternative for various UTI caused by E. coli, Klebsiella and proteus? |
|
Definition
| Cefoxitin and Cefmetazole |
|
|
Term
| Which is used for community acquired Pneumonia if related to H. Flu and Klebsiella or if its beta lactam resistant |
|
Definition
|
|
Term
| Which is used as an extended spectrum, more like first generation and for a lot of g(+) if complex infection and causes diarrhea more than other? |
|
Definition
|
|
Term
| Which generation of Cephalosporin has primary extended G(-) spectrum and have the ability to cross BBB? |
|
Definition
|
|
Term
| Which generation of Cephalosporin has primary extended G(-): Citrobacter, serratia, proidencia, and beta lactamases producing strains of H. influenza and Neisseria? |
|
Definition
|
|
Term
| Which one don't work well against strep, Pneumococcus or Staph? |
|
Definition
|
|
Term
| Which is used for Pseudomonas? |
|
Definition
| Ceftazidime and Cefoperazone |
|
|
Term
| Which is used for g(+) cocci with strep and drug is penicillin resistant? |
|
Definition
| Ceftriazone and Cefotaxime |
|
|
Term
| Which is used for Pen resistant Streptococcus and narrow spectrum streptococcus? |
|
Definition
|
|
Term
| Which is used for severe infection, g(-) ofeten resistant to other drugs? |
|
Definition
| third generation cephalosporin |
|
|
Term
| Which is given for N. gonnarrhea or strep, or pneumoniae and resistant to pen? |
|
Definition
|
|
Term
| Which is given orally if Ceftriazone not working? |
|
Definition
|
|
Term
| Which is used orally and cross BBB by Pediatrists? |
|
Definition
| Cefixime, cefpodoxime, cefditoren |
|
|
Term
| Which is other drug that can across BBB? |
|
Definition
|
|
Term
| Which one is Fourth generation cephalosporin? |
|
Definition
|
|
Term
| Which one is Fourth generation cephalosporin and great against both g(+) and g(-), pseudomonas, staph, strep,stable against beta lactamases? |
|
Definition
|
|
Term
| Which is do not cover anaerobes and enterococcus? |
|
Definition
|
|
Term
| What is the fifth generation of cephalosporin and only for MRSA? |
|
Definition
|
|
Term
| What are the side effects of using antibiotics? |
|
Definition
GI
Diarrhea, nausea
Some electrolytes balances
Thrombophlebitis: burning at the injection site due to infusion of antibiotics
Suprainfection= secondary infec, fungal infection |
|
|
Term
| What are the side effects of using cephalosporin? |
|
Definition
| Hypoprothrombinemia-low thrombin levela dn get bleeding issue |
|
|
Term
| Which drugs inhibit acetaldehyde dedydrogenase to quit drinking alcohol? |
|
Definition
|
|
Term
| What drugs have disulfiram like reaction when drinking alcohol? |
|
Definition
Metronidazole
Cefoperazone
Cefotetan
Zyvox |
|
|
Term
| What drug should be stopped if the patient has anaphylaxis but give out if just only skin rash? |
|
Definition
|
|
Term
| How is Amoxicillin is taken? |
|
Definition
| Orally three times a day and can be taken with food |
|
|
Term
| How is Ampicillin is given? |
|
Definition
| IV, 4 times a day and taken on an empty stomach an hrs before or 2 hrs after meal |
|
|
Term
| What are the mixed combination b/w beta lactamase inhibitors and PCN? |
|
Definition
| Amoxicillin/Clavulante-orally |
|
|
Term
| What are the mixed combination b/w beta lactamase inhibitors and PCN? |
|
Definition
|
|
Term
| What are the mixed combination b/w beta lactamase inhibitors and PCN? |
|
Definition
| Ticarcilin/Clavulanate-IV |
|
|
Term
| What are the mixed combination b/w beta lactamase inhibitors and PCN? |
|
Definition
| Piperacillin/Tazobactam-IV |
|
|
Term
| What is the mechanism of Beta Lactamase Inhibitor? |
|
Definition
| Bind to receptors and prevent beta lactamase enzyme from attacking beta lactam ring |
|
|
Term
| What is the purpose of combination b/w Beta Lactamase Inhibitors and PNC? |
|
Definition
| Produce a broader spectrum for antibiotics |
|
|
Term
|
Definition
Amoxillin/Clavulante-orally
and work better than aminopenicillins |
|
|
Term
| What is the indication of beta lactamase inhibitors? |
|
Definition
Weak antibacterial activity
Inhibit many but not all B-lactamases
Most effective against encoded b-lactamases produced by S. Aureus, H.Influenza, N. gonnohrea, Salmonella, Shigella, E. coli, K. Pneumonia, bacteriodes |
|
|
Term
| What is beta lactamase inhibitors not use for? |
|
Definition
| Enterobacter, citrobacter, pseudomonas, serratia |
|
|
Term
| What drugs are used to treat ga (-) Enterobacter, citrobacter, pseudomonas, serratia? |
|
Definition
| Third generation of Cephalosporin esp for pseudomonas |
|
|
Term
| What is the indication of beta-lactamase antibiotics? |
|
Definition
G (+), some g(-) and minimum anaerobes
and excellent for staph coverage |
|
|
Term
| What is another indication of beta-lactamase antibiotics, most likely augmentin orally? |
|
Definition
| For skin and soft tissue infection and primarily for immunocompromised patients b/c diabetics and HIV patients are going to have polymicrobial infection and culture is going to show more than one type of bacteria |
|
|
Term
| What is given for diabetic ingrown toenails? |
|
Definition
| Augmentin, orally (amoxicillin/Clavunic) |
|
|
Term
| What is given for healthy ingrown toenails? |
|
Definition
| First generation cephalosporin |
|
|
Term
| What do you when you do ingrown nail? |
|
Definition
| give 2g of augmentin before procedure |
|
|
Term
| What is the direction use for augmentin? |
|
Definition
ALways give twice a day
Loading dose is 500 mg tables (2g) before and 1.5 g after procedure
or 4 times a day for 5 days 500mg before procedure to get the blood level |
|
|
Term
do not take more than one augmentin at a time
and cannot load up b/c od clavulanic acid and get diarrhea |
|
Definition
|
|
Term
| What Beta lactamase Pen mainly affect G(-) but not G(+)? |
|
Definition
Ticarcillin/Clavulanate-IV
Piperacillin/Tazobactam-IV |
|
|
Term
| What are the name of Ureidopenicillin also know as superpens? |
|
Definition
Azlocillin (oral only)
Melzlocillin oral (only)
Piperracillin (oral only) |
|
|
Term
| What are drugs are not like beta-lactamase but also dover treament of severe type of infection, immunocompromised patients? |
|
Definition
|
|
Term
| What are the drugs used for triple antibiotic coverage: G(+), G(-) and anaerobe? |
|
Definition
Pipercillin
Superpen
Third generation of cephalosporin
Metronidazole |
|
|
Term
| What are drugs used for g(-) coverage like e.coli, salmonella, shigella, and not great fro pseudomonas or citrobacteria coverage? |
|
Definition
|
|
Term
| Which Fluroquinolone inhibits DNA gyrase (baterial topoiisomerase II and IV) ? |
|
Definition
|
|
Term
| Which of the following drug use for mostly g(-), chlamydia, gonnorhea, inhibition of intracellular bacteria, UTI, Prostatisis? |
|
Definition
| Fluroquinolone-Ciprofloxacin |
|
|
Term
Which drugs is toxicity to CNS stimulation, sensitivity to sunlight, interfere with xanthine derivatives, damage growing cartilage-bad for bones,
do not used under 18 or during pregnancy and cause pseudomembranous colitis, oral absorption by divalen cations, (Ca, Fe, Mg, Zn) |
|
Definition
| Fluroquinolone-Ciprofloxacin |
|
|
Term
| Which drug like ciprofloxacin used affective against G(+) and esp form community acquired Pneumonia caused by S. pneumonia |
|
Definition
|
|
