Term
| T/F Rituximab should be used cautiously in patients with cardiac conditions |
|
Definition
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|
Term
| T/F Retuximab does not have a high potention for infusion reactions |
|
Definition
|
|
Term
| As a precaution for allergic reactions, what agents should the nurse avoid during the first 2 hours of rituximab infusion? |
|
Definition
a. Amphotericin
b. Blood products
c. first dose of antibiotics. |
|
|
Term
| T/F Rituximab can be use in children and pregnant and lactating mothers? |
|
Definition
| False, This drug is not recommended. |
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Term
| Name 2 side effects or Rituximab, |
|
Definition
| Fever, chills and or headache. |
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|
Term
Rituximab is used for treatment of?
|
|
Definition
|
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Term
| Before administration, Rituximab is mixed with NS or what? |
|
Definition
|
|
Term
| Should a nurse mix the Rituximab and NS in a plastic bag or a glass container? Why? |
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Definition
| Plastic bag, the antibodies in the drug stick to the glass container. |
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Term
| One of the nurses roles during Rituximab administration is to premedicate client with what? |
|
Definition
a. Antihistamins
b. antipyretics. |
|
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Term
| Whats an example of antihistamine might be administered as a premedication? |
|
Definition
a. Ranitidine
b. diphenyhydramine |
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Term
| What should the nurse do if the patient develops infusion related effects. |
|
Definition
| Stop the infusion till effects clear then start slowly. |
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Term
| What can the nurse advise ambulatory clients to do when they arrive home after infusion. |
|
Definition
| Drink lots of luids to enhance renal excretion of tumor lysis products. |
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Term
| What advise can the nurse give to a 25 year old female who planning to get married in a month? |
|
Definition
| Use birth control measures for 12 months. |
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|
Term
| Again, the nurse should premedicate the patient with what? |
|
Definition
| Tylenol, and Antihistamines. |
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|
Term
| What type of a drug is Trastuzumab (Herceptin)? |
|
Definition
| Humanized monoclonal antibody. |
|
|
Term
| Trastuzumab is used for what type of cancer? |
|
Definition
|
|
Term
| T/F Trastuzumab (Herceptin) administration starts with a loading dose. |
|
Definition
|
|
Term
| The loading dose of Trastuzumab (Herceptin) is... |
|
Definition
| 4mg/kg of body wt given over 90 mins. |
|
|
Term
| Whats the subsequent weekly dose of Trastuzumab (Herceptin)? |
|
Definition
| 2mg/kg of body wt over 20 mins. |
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|
Term
| Bevacizumab (Avastin) is a monoclonal antibody to target what? |
|
Definition
|
|
Term
|
Definition
| A protein responsible for stimulation of new blood vessels. |
|
|
Term
| Whats the fancy name/word for Bevacizumab (Avastin) |
|
Definition
|
|
Term
| Whats one important thing should the nurse do during administration and why? |
|
Definition
| Cover the drug because its light sensitive. |
|
|
Term
Below are some adverse effects. Choose all that apply to Bevacizumab (Avastin).
a. Asthenia
b. HA
c. HTN
d. anorexia
e. diarrhea
f. leukopenia
g. proteinuria. |
|
Definition
|
|
Term
| T/F Why should the nurse advise a surgery candidate to post pone surgeries while receiving Bevacizumab (Avastin) |
|
Definition
| Leukopenia is an know adverse effect. |
|
|
Term
| What type of a drug is Cetuximab (Erbitux) |
|
Definition
| Chimeric monoclonal antibody |
|
|
Term
| T/F Cetuximab (Erbitux) works by targeting EGRF sites |
|
Definition
|
|
Term
| T/F Cetuximab (Erbitux) also works by depriving both malignant and normal tissues of cytokines. |
|
Definition
| True (This enhances mutant cell death) |
|
|
Term
| Is Cetuximab (Erbitux) used to treat colorectal cancer or breast cancer. |
|
Definition
|
|
Term
| T/F Cetuximab (Erbitux) can be administered as a combo therapy. i.e. infusion and radiation. |
|
Definition
|
|
Term
| A client is walks in for their Cetuximab (Erbitux) infusion but expresses concerns on how he will tolerate. What should the nurse say? |
|
Definition
| Cetuximab (Erbitux) is tolerated well by most people and that he will be closely monitored. |
|
|
Term
What electrolyte imbalance may occur after within 2 weeks of Cetuximab (Erbitux) administration?
a. Hypocancemia
b. Hypokalemia
c. Hypomagnesia
d. Hypernatremia. |
|
Definition
|
|
Term
| T/F Panitumumab (Verctibix) is administered for coloretal cancer and its side effects as similar to cetuximab. |
|
Definition
|
|
Term
| Alemtuzumab (campath 1-H) is administered for what cancer? |
|
Definition
|
|
Term
| T/F Alemtuzumab (campath 1-H) is administer by infusion for 2 hours QD untill toxicity is reached. |
|
Definition
|
|
Term
| What should the nurse watch for in a client receiving Alemtuzumab (campath 1-H)? |
|
Definition
| Infusion allergic reactions. |
|
|
Term
| T/F Alemtuzumab (campath 1-H) may be administered sub Q |
|
Definition
| True. there is less frequent reactions. |
|
|
Term
| What lab is used to determine when to discontinue the therapy. |
|
Definition
|
|
Term
| Before a client is sent after therapy of Alemtuzumab (campath 1-H), its critical that they receive a .........treatment. |
|
Definition
| Antimicrobial prophylaxis. |
|
|
Term
| T/F Abciximab (ReoPro) is used to treat bone cancer. |
|
Definition
| False, this drug has no antitumor function. |
|
|
Term
| T/F Abciximab (ReoPro) inhibits platelet aggregation? |
|
Definition
|
|
Term
| Do immune modulator drugs act by stimulating or suppressing the immune system. |
|
Definition
|
|
Term
| Whats cyclosporine used for? |
|
Definition
| An adjunct treatment to prevent organ rejection. |
|
|
Term
| What are some factors that affect cyclosporin bioavailability? |
|
Definition
| Food, and enterohepatic circulation |
|
|
Term
| T/F Ingesting Cyclosporine with food hing in fat may increase bioavailability. |
|
Definition
|
|
Term
| T/F Cyclosporine is mainly excreted via the renal system. |
|
Definition
| False, Excreted is primarily biliary |
|
|
Term
Does Cyclosoporing affects both humoral and cell-mediated immunity. |
|
Definition
|
|
Term
| T/F Pts taking cyclosporine at home should be advised to take the drug at the same time every day. |
|
Definition
|
|
Term
| Name one nursing dx for a pt receiving cyclosporine |
|
Definition
| Risk for infection r/t immunosuppression. |
|
|
Term
| T/F Pt. taking cyclosporine at home orally should use a class container to mix in a glass container. |
|
Definition
|
|
Term
| Name an example of oral cyclosporine |
|
Definition
|
|
Term
| Pts are allowed to mix sandimmune with orange juice or apple juice instead of water? |
|
Definition
| True, this improves the flavor. |
|
|
Term
Which of the following is not an adverse effect of cyclosporine.
a. Renal dysfunction
b. Tremors
c. HA
d. HTN
e. Hirsutism
f. Gum hyperplasia |
|
Definition
|
|
Term
| T/F Tacrolimus is closely related to cyclosporine |
|
Definition
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