| Term 
 | Definition 
 
        | drugs that prevent clot formation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | drugs that prevent platelet aggregation |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | drugs that eliminate clots |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | PO drug that interferes with specific vit K dependant clotting factors |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV drug that inhibits formation of fibrin clots (turns off clotting pathways) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | SubQ drug that produces a very stable response for anticoagulation with less chance of bleeding than heparin |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | antidote for heparin and LMWH - given IV over 10 minutes
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | when giving protamine sulfate (Heparin and LMWH antidote) the nurse should watch for |  | 
        |  | 
        
        | Term 
 
        | vitamin K - whole blood - platelets |  | Definition 
 
        | antidote for warfarin (coumadin) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | for Heparin, clotting time should be _____ faster than control time |  | 
        |  | 
        
        | Term 
 
        | APTT (activated partial thromboplastin time) |  | Definition 
 
        | lab test used to check clotting factors in IV or SC Heparin |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | for LMWH (lovonox), clotting time should be _____ faster than control time |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | for Warfarin (coumadin), clotting time should be _____ faster than control time |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | lab test used to check clotting factors in Lovonox |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | lab tests used to check clotting factors in warfarin (coumadin) |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | preferred antiplatelet - prolongs bleeding time |  | 
        |  | 
        
        | Term 
 
        | eptifibatide (intergrillin) |  | Definition 
 
        | antiplatelet used to treat unstable angina acute coronary syndrome |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | another name for thrombolytics |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | thrombolytics convert plasminogen to ________ which prevents tissue necrosis |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | enzyme that breaks up clots when thrombolytics are used |  | 
        |  | 
        
        | Term 
 
        | alteplase recombinant (Activase) |  | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | activase(thrombolytic) must be given within ____ of an MI and ____ of thrombotic stroke |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Heparin doses are adjusted _____, based on APTT |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | when beginning treatment, a loading dose of _______ may be given, followed by warfarin |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | postop anticoagulant therapy may last up to ________ |  | 
        |  | 
        
        | Term 
 
        | extra pressure for 30 minutes - bandages |  | Definition 
 
        | inverventions for bleeding at IV site with anticoagulants |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | with anticoagulants, pt should limit food high in ___________ |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | antiplatelets should be stopped ______ prior to surgery |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | preffered type of drugs for hypertension |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | drugs that supress the renin-angiotensin system.  Stop Angiotensin I to Angiotensin II so Na and water are excreted = decrease BP |  | 
        |  | 
        
        | Term 
 
        | ARBs (angiotensin II receptor blockers) |  | Definition 
 
        | drugs that stop the binding of angiotensin II at receptor sites |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | IV drug given for hypertensive crisis - no time to wait for PO to work
 |  | 
        |  | 
        
        | Term 
 
        | ulcers, GI upset, anorexia, constipation |  | Definition 
 
        | GI adverse effects of ACE inhibitors |  | 
        |  | 
        
        | Term 
 
        | Rash, pertusis, cough, dry mouth, tahycardia, hypotension, neutropenia |  | Definition 
 
        | non-GI adverse effects of ACE inhibitors |  | 
        |  | 
        
        | Term 
 
        | edema, H/A, flushing, nausea, constipation, nervousness |  | Definition 
 
        | non-cardiac adverse effects of Ca channel blockers |  | 
        |  | 
        
        | Term 
 
        | bradycardia, hypotension, arrhythmias |  | Definition 
 
        | cardiac adverse effects of calcium channel blockers |  | 
        |  | 
        
        | Term 
 
        | hypotension, upper respiratory symptoms, cough |  | Definition 
 
        | adverse effects of ARBs (angiotensin receptor blockers) |  | 
        |  | 
        
        | Term 
 
        | verapamil (Ca channel blocker) |  | Definition 
 
        | antihypertensive that should be given with food |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | these antihypertensive drugs can not be taken by someone who is pregnant or may become pregnant |  | 
        |  |