Shared Flashcard Set

Details

Pharm Anat and Phys 2
Second Set of Notecards for A&P
37
Pharmacology
Graduate
09/02/2014

Additional Pharmacology Flashcards

 


 

Cards

Term
Karyotype
Definition
an organism's chromosomal complement/morphology
Term
Chromosome
Definition
organization of genes on 1 unit in the cell nucleus
Term
Gene
Definition
one hereditary unit, codes for 1 functional product, which is a protein
Term
Allele
Definition
an alternative form of a gene, one of a piar where 2 alleles make the gene
Term
Locus
Definition
a precise position within the linear order of DNA
Term
Haplotype
Definition
a set of DNA variations that tend to be inherited together, in a relative sequence.
Term
Penetrance
Definition
probability that a gene will have any phenotypic expression at all
Term
Expressivity
Definition
The severity of the phenotype, there can be variable phenotypic expressions amongst the alleles of any one gene
Term
Resting Membrane Potential, Local potential, Depolarization Threshold, "Charged"
Definition
Resting: -70mV
Local potential: -68mV
Threshold: -55mV
Charged: +35mV
Term
Hyperpolarization
Definition
After Na+ pump pushes out excess the resting membrane potential returns to resting, or a bit below
Term
Action Potential Speed: Myelinated vs Non-Myelinated
Definition
100m/s vs 1m/s
Term
Nodes of Ranvier
Definition
Gaps in myelin sheath; ion channels cluster here
Term
Saltatory Conduction
Definition
skip/jump; like the action potention with the myelination
Term
Stimulatory/excitatory synapses
Definition
nt binding causes post-synaptic cell to be depolarized: na influx ca influx, more positive ions enter so new AP is generated
Term
Inhibitory Synapses
Definition
Nt binding causes post-synaptic cell to be hyperpolarized cl-influx, k+ efflux
Term
Synaptogenesis
Definition
genes coding for new synapses are expressed when synapses are repeatedly fired
Term
Blood-Brain barrier
Definition
tight junctions between capillary endothelial cells, stimulated to form by astrocytes (glial cells). Protects brain by keeping many large molecules in blood, and away from neurons
Term
Frontal Lobe
Definition
primary motor cortex, motor association area, Broca's motor/expressive speech/language area, prefrontal cortex
Term
Motor association area
Definition
(Frontal lobe) motor plans and programs; motor memory - hard drive for motor skills
Term
Broca's motor/expressive speech area
Definition
language region responsible for expressive language, allows you to produce speech. (Frontal lobe, left hemisphere)
Term
Prefrontal Cortex
Definition
thinking, planning, problem-solving, impulse control, executive function, working memory, inner adult
Term
Parietal Lobe
Definition
Behind frontal lobe:primary somatosensory cortex, somatosensory association cotex, parieto-temporal association cortex
Term
Primary somatosensory cortex
Definition
perception of somatosensation from body and face: pain, temperature, pressure, position sense
Term
Somatosensory association cortex
Definition
interprets somatosensory information = stereognosis: body part ownership and body image
Term
Parieto-temporal association cortex
Definition
abstract thought, reading, writing, mathematics ; connects to temporal lobe
Term
Occipital lobe
Definition
primary visual cortex, visual association cortex
Term
Temporal lobe
Definition
primary auditory cortex, auditory association cortex, wernicke's sensory (receptive) speech area, hippocampus, amygdala
Term
Wernicke's sensory (receptive) speech area
Definition
understanding of speech and language, usually in left hemisphere
Term
Limbic System
Definition
overlaps frontal, parietal, temporal. Responsible for emotions, preferences, personality, memory. Who you are as a person
Term
Amygdala
Definition
protects us from danger; responsible fro strong negative emotions: fear, rage/anger, disgust, shame
Term
Hippocampus
Definition
formation of longterm memories: learning; right hippo is spatial, left hippo is verbal
Term
Thalamus
Definition
sensory processing, connects sensation to emotion and thought (diencephalon)
Term
Hypothalamus
Definition
controls endocrine system, controls autonomic nervous system
Term
Brainstem
Definition
midbrain, pons, medulla oblongata
Term
Midbrain: Substantia nigra
Definition
produces dopamine
Term
Dural septa
Definition
folds, contain spaces. Dural sinuses contain venous blood from the brain
Term
Circle of willis
Definition
provides redundancy; blood to all parts of cortex via cerebral arteries; little overlap
Supporting users have an ad free experience!