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pharm 20-26
pharm20-26
50
Pharmacology
Undergraduate 3
07/15/2011

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Cards

Term

prototype for benzodiazapenes

used as anxiolytics

Definition
diazepam (valium)
Term

what adverse effects can

benzodiazepines have on the elderly

Definition
increased anxiety
Term

what are important drug interactions

with benzodiazapines?

Definition

the affects of benzodiazapenes are increased with the

use of cimetidine and oral contraceptives. these are

also weakend by benzo

Term
what is the prototype for barbiturates?
Definition
phenobarbital
Term
what are phenobarbitals therapeutic affects?
Definition

anti anxiety, sedative, hypnotic, long term

seizure control

Term

what effect does phenobarbital

have on pain meds?

Definition

can help effects of pain meds

by calming patient

Term

what is the prototype for tricyclic

antidepressants?

Definition
imipramine
Term
what is imiprine therapuetic affects?
Definition
first drug developed to fight depression
Term
what are anticholinergic side effects?
Definition
dry mouth, constipation, nausea, vomiting,
Term
what are trycliclic antidepressants actions?
Definition

block the reuptake of norepinephrine

and seratonin

Term

what are contraindications/adverse effects of

tricyclic antidepressants?

Definition

anticholinergic effects, dont give

to preganant women

Term

what are important drug interactions with

tricyclic antidepressants?

Definition

increases anticoagulants effects, if combined

with sympathomimetics increased risk of

arrythmias and hypertension

Term

what is the prototype for selectrive seratonin

reuptake inhibitors?(ssri)

Definition
fluoxetine(prozac)
Term
why are ssri's a better choice than tca's
Definition
less adverse effects
Term
what are ssri's therapeutic effects?
Definition

treat depression, alcoholism, ocd,

panick attacks, eating disorders

Term
what are the three maoi's
Definition
marplan, nardil, parnate
Term
what are the therapeutic effects of maoi's?
Definition

treatment of depressants not responsive

to other agents

Term

what foods do you need to avoid while

taking maoi's? why

Definition

foods containing high amounts of tyramine,

causes severe hypertension

Term

what are important drug interactions

with maoi's?

Definition
should not be taken with other antidepressents ssri's,tca's
Term

what is the prototype for

typical antipsychotics?

Definition
chlorpromazine
Term
what are pyramidal side affects?
Definition

tremors, restlesness, involuntary movements,

muscular ridgidity

Term

what is the prototype for

atypical antipsychotics?

Definition
clozapine
Term

what is the difference between typical

and atypical antipsycotics?

Definition

typical justs blocks dopamine, atypical blocks

dopamine and seratonin, the dual actions

of atypical reduce adverse neuro effects

and depression

Term
what are adverse effects of antipsycotics?
Definition
sedation, extrapyramidal, anti cholinergic effects
Term
what are contraindications of antipsycotics?
Definition

parkinsons, coronary disease, hypotension,

bone marrow suppression

Term
what is the protype for antimanic drugs?
Definition
litheum
Term

what is the difference between im and

po admin in antipsycotics?

Definition

im stays in system 4 to 5 times longer

up to six months

Term
what are the adverse affects of litheum?
Definition

highly toxic, renal toxicity, pulmonary toxicity,

cns problems include lethargy slurred speach

muscle weakness can limit side effects by

staying hydrated

Term

what drug should you not give

with litheum? why?

Definition
haldol , irreversable brain damage
Term
what is the prototype for cns stimulants?
Definition
methylphenidate (ritalin)
Term
what are cns stimulants used to treat?
Definition

treatment of attention deficit disorders

and narcolepsy

Term
what is the prototype for hydantoins?
Definition
phenytoin(dilantin)
Term
what do hydantoins treat?
Definition
treat tonic-clonic seizure, prevent epilepticus
Term
what are conraindications of hydantoins?
Definition
pregnancy, cause birth defects
Term
what are adverse effects of phenytoin?
Definition

confusion, drowsiness, fatigue, cardiac arrythmias,

+gingival hyperplasia+

Term

what is the prototype for barbituates

that treat seizures?

Definition
phenobarbital
Term

what is the prototype for benzodiazepines

that treat seizures?

Definition
diazepam(valium)
Term
what are diazepam's therapeutic affects?
Definition
management of anxiety, acohoil withdrawl, muscle relaxant, antiepilectic, treatment of tetanus
Term

what two drugs are commonly given in

combo to treat seizures ?

Definition
phenobarbital and phenytoin(dilantin)
Term

what is the prototype for dopaminergic

agents for parkinsons?

Definition
levadopa
Term

what is the prototype foranticholinergic

agents for parkinsons?

Definition
biperiden
Term
what does biperiden do?
Definition

helps minimize secondary effects

of parkinsons treatment

Term

what are important drug interactions

with biperiden?

Definition

tricyclic antidepressants and phenothiazines due

to there anticholinergic effects

Term

what is the prototype for centrally acting

skeletal muscle relaxants?

Definition
carisoprodol(soma)
Term

what is the prototype for direct acting

skeletal muscle relaxants?

Definition
dantrolene
Term
what is the prototype for narcotic agonists?
Definition
morphine
Term

what is the adverse effects for

agonist narcotics?

Definition
respitory depression, constipation,
Term
what is the prototype for narcotic antagonists?
Definition
naloxone(narcan)
Term
what is the prototype for antimigrane meds?
Definition
sumatriptan(imitrex)
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