Term
|
Definition
| NE release and deplete (Indirect acting Sympathomimetic) |
|
|
Term
Amphetamine and Ephedrine
Phenylpropanolamine |
|
Definition
| Mixed action Sympathomimetic |
|
|
Term
|
Definition
Carbonic Anhydrase inhibitor
(proximal tubule, blocks CA!)
Dcr. HCO3, Alkaline urine, incr. K excretion. |
|
|
Term
Hydrochothiazide
Chlorthalidone |
|
Definition
Thiazide Diuretic
Inhibit NA, CL symport in DISTAL tubule
Side Effects:
Hypokalemia, hyperuricemia!!! |
|
|
Term
|
Definition
LOOP DIURETIC!
MOST EFFICACEOUS!
INHIBITS: NA - K - 2CL transporter, ASCENDING loop!
Side effects:
Hypokalemia, metabolic alkylosos.
Profound diuresis, electrolyte imbalance. |
|
|
Term
|
Definition
Potassium Sparing Diuretic
Acts in COLLECTING DUCT: Decr. K +, Incr NA Excretion!
Side Effects:
HyperKALEMIA! |
|
|
Term
|
Definition
Carbonic Anhydrase Inhibitor
Loop Diuretic
Thiazide Diuretic
Potassium Sparing |
|
|
Term
Drugs used as Anti- Hypertensives:
( 5 ) |
|
Definition
1- Diuretics
2- Blockers of Sympathetic NS
3- Blockers of RAS
4- Vasodilators
5- Ca+ Channel Blockers |
|
|
Term
|
Definition
Alpha 2 Agonist
Decreases SNS outflow (Decr NE, renin, HR, and CO) |
|
|
Term
| Side Effects of Alpha 2 Agonist |
|
Definition
(Ex: Clonadine, Quanabenz)
D3: Dry Mouth, Dizziness, Drowsy. |
|
|
Term
|
Definition
Adrenergic Neuron Blockers
---> PREVENT NE RELEASE!
May cause OH! |
|
|
Term
|
Definition
Alpha Blockers
Work by: Decrease resistance, increase venous capitance!
Side Effect:
H20, Na retention. OH, dizzy, tachycardia. |
|
|
Term
| Propanolol, pindolol, nadolol |
|
Definition
Beta blockers!
(Decr. HR, contractitility, Renin Release!) |
|
|
Term
| Renin Inhibitors, ACE inhibitors, and Angiotension receptor blockers are all ___________ (type of drug). |
|
Definition
| Blockers of the RENIN ANGIOTENSIN SYSTEM |
|
|
Term
| Captopril, enalapril, benazopril, lisinopril |
|
Definition
ACE Inhibitors
Work by decr: TPR, ALdostorone/
Incr: Renal blood flow (for diuresis) |
|
|
Term
Losartan
Valsartan
Candesartan |
|
Definition
| Angiotensin receptor blockers |
|
|
Term
| Hydralazine and Minoxidil are _____ that work by dilating ______ |
|
Definition
| Vasodilators, work by arteriolar dilation. |
|
|
Term
|
Definition
A venous/arteriolar dilator
Side Effects may include: Postural hypotension, reflex tachycardia. |
|
|
Term
Losartan
Valsartan
Candesartan |
|
Definition
| Angiotensin Receptor Blocker |
|
|
Term
Nifedipine
Verapamil
Diltiazem
Felodipine |
|
Definition
|
|
Term
| Antihypertensives can cause |
|
Definition
Hypotension , or OH!
Watch for loss of exercise tolerance |
|
|
