Term
|
Definition
|
|
Term
| CVS effects of amphetamine |
|
Definition
Displacement of norepinephrine acts on postsynaptic alpha and B1 receptors
Effects:
Fight or flight, increased blood pressure, increased heart rate |
|
|
Term
| CNS effects of amphetamine |
|
Definition
Behavioural and psychomotor stimulation
Anorexia
Hyperthermia
Respiratory centre stimulation
Increase neurotransmission in spinal cord, convulsions |
|
|
Term
| Amphetamines act on brain areas |
|
Definition
| Reticular activating system, medial forebrain bundle, hypothalamus, limbic system |
|
|
Term
| Therapeutic uses for amphetamine-like drugs |
|
Definition
Narcolepsy, ADHD, some Parkinson's
Methylphenidate drug of choice for narcolepsy and ADHD |
|
|
Term
| Short Term Effects Amphetamine |
|
Definition
Low:
Overstimulation, restlessness, dizziness, insomnia, euphoria, mild confusion, irregular heartbeat, headache, increase BP, increased respiratory rate
Higher:
Increased exhilaration and euphoria, psychosusm hallucinations, heart attack, angina, dysrhythmias, change in BP and fainting |
|
|
Term
| Long Term Effects Amphetamine |
|
Definition
| Chronic sleeping problem,anxious and tense,poor appetite, BP elevated, suspicious and paranoid |
|
|
Term
|
Definition
Alkaloid from cocoa bush, local anesthetic and CNS stimulant
Differences from amphetamines
- shorter duration
- lower incidence complications
- tolerance does not develop as readily |
|
|
Term
|
Definition
Low:
Dilation of pupils, exaggerated reflexes, euphoria, well-being, reduced appetite and need for sleep, increased self-confidence, vasoconstrction, increased respiratory rate
Higher:
Intense euphoria followed by severe agitation, anxiety, rapid flight of ideas, feelings of grandiosity, paranoid thinking, psychosis, tremour and muscle twitches, high blood pressure, nausea and vomiting, pulmonary edema, acute renal failure, elevated body temp, cold sweat |
|
|
Term
|
Definition
| Mood swings, psychosis, hallucinations, sleep and eating disorders, sexual function impaired, high blood pressure, irregular heart rhythm |
|
|
Term
|
Definition
Increases mental performance, decreases drowsiness and fatigue
Block adenosine receptors |
|
|
Term
|
Definition
Low:
Elevate mood, reduce fatigue,constriction cerebral blood vessels,
High:
Irritability, restlessness, nervousness, insomnia, rambling, psychomotor agitation, rapid and irregular heartbeat |
|
|
Term
|
Definition
| Restlessness, nervousness, insomnia, increased urinary output, gastric upset, rambling speech and thought |
|
|
