Shared Flashcard Set

Details

Peptic Ulcer Disease
PUD
8
Pharmacology
Professional
10/09/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
First line tor H. Pylori Ulcers
Definition
3 Drug Regimen for 7-14 days
Term
3 Drug Regimen for H. Pylori Ulcer Eradication
Definition
PPI, Clarithromycin, Amoxicillin

or

PPI, Clarithromycin, Metronidazole
Term
4 Drug Regimen for H. Pylori Ulcer Eradication
Definition
2nd line if 1st line fails or cannot tolerate

PPI + Bismuth Subsalicylate + Metronidazole + Tetracycline (or Amoxcicillin or Clarithromycin)
or
H2RA +Bismuth Subsalicylate + Metronidazole + Tetracycline (or Amoxcicillin or Clarithromycin)
Term
1st step of treatment for NSAID Induced Ulcer
then...
Definition
D/C offending non-selective NSAID
Then initiate:
H2RA, PPI, Sucralfate

PPI have the most rapid relief from symptoms.
Term
Treat NSAID Ulcer if you must continue the NSAID
Definition
Continue the NSAID:
1) Decrease the dose
2) change to paritally selective COX 2
3) PPI is DOC if you must continue NSAID
Term
Treat NSAID Ulcer if you must continue the NSAID
Definition
Continue the NSAID:
1) Decrease the dose
2) change to paritally selective COX 2
3) PPI is DOC if you must continue NSAID (Better tolerated than misoprostal and superior to H2RA)
4) Change to COX-2 selective (Celecoxib
5) May use Cox2 with PPI in very high risk patients
Term
How to treat Peptic Ulcer Bleeding
Definition
Treatment Endoscopy
Antisecretory therapy with PPI (clots are less stable in high acid conditions)
Do 80mg loading dose and then 8mg/hr CI x 72 hours ( Omeprazole used)
Term
Who to Prophylax for Stress Related Mucosal Bleeding?
Definition
1. Mechanical Vent > 48 hours
2. Coagulopathy (Warfarin, Clopidagrel, AsA)
3. Hypotension
4. Sepsis
5. Hepatic Failure
6. Acute Renal Failure
7. Multiple Trauma
8. Severe Burns >35%
9. Head Injury
10. Traumatic Spinal Cord injury.
11. History of GI bleed
Supporting users have an ad free experience!