Term
Gram positive cocci (strep, enterococcus)
Gram negative cocci (Neisseria men)
Gram positive bacilli (Bacillus anthracis and Listeria monocytogenes)
Tetanus (Clostridum tetani)
Gram negative bacilli (Pasteurella, Fusobacterium, Streptobacillus)
Weil's disease (Leptospira)
Actinomyces (actinomyces israelii) |
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Definition
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Term
| in combination with an aminoglycoside for enterococcal endocarditis (Enterococcus) |
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Definition
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Term
| minor infections (Streptococcus pyogenes) and penicillin sensitive pneumococci) |
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Definition
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Term
| Oral use for oropharyngeal infections (pharyngitis, tonsillitis, SCARLET FEVER, URTIs (otitis media, sinusitis), skin and soft tissue infections |
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Definition
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Term
| Upper respiratory tract infections and otitis media due to susceptible streptococci and pneumococci |
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Definition
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Term
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Definition
| Benzathine penicillin G (Bicillin L-A) |
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Term
| Benzathine penicillin G name |
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Definition
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Term
Benzathine penicillin G/Procaine penicillin G
trade name |
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Definition
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Term
| Very narrow spectrum penicillins resistant to staphylococcal B-lactamases |
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Definition
| Nafcillin, Oxacillin, Dicloxacillin |
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Term
| Use limited to infections due to penicillinase producing staphylococci |
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Definition
| Nafcillin, Oxacillin, Dicloxacillin |
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Term
| For serious systemic staph infections (bacteremia, endocrditis, meningitis, RTIs, skin and soft tissue, bone and joint infections, UTIs, given by intermittant IV |
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Definition
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Term
| Acid stable and can be given orally for skin and soft tissue infections, bone and joint infections, UTIs, RTIs |
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Definition
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Term
Increased activity vs gram negative bacilli (E. Coli, Proteus irabilis, Haemophilus influenze, Salmonella, Shigella)
gram neg cocci (Moraxella catarrhalis)
HEMPSS |
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Definition
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Term
| commonly employed in treatment of UTIs, ottis media, sinusitis, bronchitis, pneumonia |
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Definition
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Term
| UTIs and bacterial cystitis due to (E. Coli, Proteus mirabilis, and Enterococcus) |
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Definition
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Term
Otitis media/respiratory tract infections (sinusitis, bronchitis, pneumonia, CAP, pharyngitis and tonsilitis)
strep pyo, strep neumo, Haemophilus influenze, Moraxella catarrhalis |
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Definition
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Term
| trade name Amoxicillin/Potassium clavulanate |
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Definition
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Term
| trade name Ampicillin/Sulbactam sodium |
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Definition
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Term
| Indicated for Helicobacter pylori (prevpac) , Pasteurella, Borellia burgdorferi (lyme dis) |
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Definition
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Term
Surgical pretreatment in patients w/ atypical heart valves undergoign oral surgery
(prophalaxis of endocarditis) |
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Definition
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Term
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Definition
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Term
| indicated for tonsillitis and pharyngitis due to Strep pyogenes |
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Definition
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Term
indicated for Salmonella, Sigella
and Campylobacter fetus |
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Definition
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Term
| resistance due to enzymatic hydrolysis by plasmid mediated B lactamase (penicillinase) |
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Definition
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Term
W/ B-lactamase inhibitor extends spectrumto include
E. Coli, Haemophilus influenza, Moraxella catarrhalis, Pasteurella |
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Definition
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Term
| trade name Ticarcillin/Potassium clavulanate |
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Definition
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Term
| First line agent for treating Psuedomonas aeruginosa |
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Definition
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Term
| Activity vs several gram-negative bacilli (including Bacteroides) but inactive vs. Klebsiella, since it produces constitutive penicillinase |
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Definition
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Term
Broadened antimicrobial activity to include penicillinase producing organisms
E. Coli and Klebisella pneumonia
RTIs, intra-abdominal infections, bacteremia, UTIS |
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Definition
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Term
| trade name Piperacillin/tazobactam sodium |
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Definition
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Term
| most potent antispeudomonal drug |
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Definition
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Term
| First line agent for psuedomonas aeruginosa |
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Definition
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Term
Also active vs. several gram negative organisms:
Klebsiella pneumo, Enterobacter, Serratia, Citrobacter, Bacteriodes |
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Definition
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Term
| broadened activity vs. E. Coli |
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Definition
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Term
| Unlike its sister drug does nto need to be combined w/ b-lactamase inhibitor for activity vs. Klebsiella pneumoniae |
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Definition
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Term
| B lactams increase permeability of bacterial cells to increase entry of |
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Definition
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Term
| may be consitutive or acquired by intro of plasmids |
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Definition
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Term
| MRSA, enterococci, and penicillin-resistant Pneumococci have developed |
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Definition
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Term
| must be administered IV or IM |
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Definition
| Unasyn, penicillin G, Timentin, Zosyn |
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Term
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Definition
| Penicillin V, dicloxacin, amoxicillin, Augmentin |
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Term
| food reduces absorption of most orally administered penicillins except for |
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Definition
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Term
| blocks renal tubular secretion of penicillins - used to prolong duratin of action |
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Definition
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Term
| predominantly excreted via biliary route |
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Definition
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Term
| eliminated through both renal and biliary routes |
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Definition
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Term
| Diarrhea most common with |
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Definition
| extended spectrum, anti-pseudomonal |
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Term
| all can create nephrotoxicity especially |
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Definition
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Term
May cause ___if administered intrathecally
or elevated serum due to renal conc. |
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Definition
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Term
| Decreased agglutination has been observed (platelet dysfunction) with |
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Definition
| piperacillin, ticaracillin, penicillin G |
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Term
| super infections can be seen with use of |
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Definition
| extended spectrum and antispeudomonal penicillins |
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Term
| Which penicillins cover anaerobes (including bacteroides fragilis) |
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Definition
those w/ betalactimase inhibitors
Augmentin, Timentin, Unasyn, Zosyn |
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